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| 1 | Reactivation of hepatitis B after liver transplantation: Current knowledge, molecular mechanisms and implications in management显示文摘Chronic hepatitis B(CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma(HCC). Liver transplantation(LT) is considered gold standard for treatment of hepatitis B virus(HBV)-related liver failure and HCC. However, post-transplant viral reactivation can be detrimental to allograft function, leading to poor survival. Prophylaxis with high-dose hepatitis B immunoglobulin(HBIG) and anti-viral drugs have achieved remarkable progress in LT by suppressingviral replication and improving long-term survival. The combination of lamivudine(LAM) plus HBIG has been for many years the most widely used. However, life-long HBIG use is both cumbersome and costly, whereas long-term use of LAM results in resistant virus. Recently, in an effort to develop HBIG-free protocols, high potency nucleos(t)ide analogues, such as Entecavir or Tenofovir, have been tried either as monotherapy or in combination with low-dose HBIG with excellent results. Current focus is on novel antiviral targets, especially for covalently closed circular DNA(ccc DNA), in an effort to eradicate HBV infection instead of viral suppression. However, there are several other molecular mechanisms through which HBV may reactivate and need equal attention. The purpose of this review is to address post-LT HBV reactivation, its risk factors, underlying molecular mechanisms, and recent advancements and future of anti-viral therapy. | Ranjit Chauhan Shilpa Lingala Chiranjeevi Gadiparthi Nivedita Lahiri Smruti R Mohanty Jian Wu Tomasz I Michalak Sanjaya K Satapathy | 2018 | World Journal of Hepatology2018,10,3: | 5 |
| 2 | Beneficial effects of tumor necrosis factor - alpha inhibition by pentoxifylline on clinical, biochemical, and metabolic parameters of patients with nonalcoholic steatohepatitis显示文摘 | Satapathy SK Garg S Chauhan R | 2004 | Am J Gastroenterol2004,99,10: | 1 |
| 3 | Profile of chronic hepatitis B virus in children in India:experience with 116 children显示文摘 | Satapathy SK Garg S Chauhan R | | 0,,: | 1 |
| 4 | Runoff and sediment yield modelling for a treated hillywatershed in eastern Himalaya using the water erosionprediction project model显示文摘 | SINGH R K PANDA R K SATAPATHY K K | 2012 | Water Resour Manage2012,26,: | 1 |
| 5 | Morphology and fracture behaviour of polyethylene/ Mg-Allayered double hydroxide ( LDH ) nanocomposites 显示文摘 | COSTA F R SATAPATHY B K WAGENKNECHT U | 2006 | European Polymer Journal2006,42,: | 1 |
| 6 | World- class logistics: managing continuous change(DIAL)显示文摘 | SATAPATHY G SOUNDAR R T K MOORE L M | 2011 | Ex- pert Systems with Applications2011,14,8: | 1 |
| 7 | IAT armature development显示文摘 | McNab I R Crawford M Satapathy S | 2011 | IEEE Transactions on Plasma Science2011,39,1: | 1 |
| 8 | Tough- to-brittle Transition in Multiwalled Carbon Nanotube (MWNT)/Polycarbonate Nanocomposites 显示文摘 | Satapathy B K Weidisch R Potsehke P | 2007 | Compo- sites Science and Technology2007,67,5: | 1 |
| 9 | Beneficial effects of tumor necrosis factor - alpha inhibition by pentoxifylline on clinical, biochemical, and metabolic parameters of patients with nonalcoholic steatohepatitis 显示文摘 | Satapathy SK Garg S Chauhan R | 2004 | Am J Gastroenterol2004,99,10: | 1 |
| 10 | Distributed intelligent architecture for logistics (DIAL) 显示文摘 | Goutam Satapathy Kumara Soundar R T Leah M Moore | 1998 | Expert Systems With Applications1998,14,4: | 1 |
| 11 | Use of direct-acting antiviral agents in hepatitis C virusinfected liver transplant candidates显示文摘Since the advent of direct acting antiviral(DAA) agents, chronic hepatitis C virus(HCV) treatment has evolved at a rapid pace. In contrast to prior regimen involving ribavirin and pegylated interferon, these newer agents are highly effective, well-tolerated, have shorter course of therapy and safer essentially in all HCV patients including those with advanced liver disease and following liver transplantation. Clinicians caring for HCV-infected patients on the liver transplant(LT) waitlist are often faced with a dilemma whether to treat HCV infection before or after liver transplantation. Sustained virological response(SVR) rates following HCV treatment may improve hepatic function sufficiently enough to negate the need for LT in certain patients. On the other hand, the decrease in MELD without improvement in quality of life in certain patients may lead to delay or dropout from potentially curative LT surgery list. In this context, our review focuses on the approach to and optimal timing of DAA-based treatment of HCV infection in LT candidates in the peri-transplant period. | Chiranjeevi Gadiparthi George Cholankeril Brandon J Perumpail Eric R Yoo Sanjaya K Satapathy Satheesh Nair Aijaz Ahmed | 2018 | World Journal of Gastroenterology2018,24,3: | 1 |
| 12 | Studies on a compression- absorption heat pump for simultaneous cooling and heating显示文摘 | Satapathy P K Gopal M R Arora R C | 2004 | lnternational JournalofEnergyResearch2004,28,: | 1 |
| 13 | Hydrotalcite catalysis in ionic liquid medium:A recyclable reaction system for heterogeneous Knoevenagel and nitroaldol condensation 显示文摘 | Khan F A Dash J Satapathy R | 2004 | Tetrahedron Letters2004,45,15: | 1 |
| 14 | Development of a naval railgun 显示文摘 | McNab I R Stefani F Crawford M Erengil M Persad C Satapathy S Vanicek H Watt T Dampier C | 2005 | IEEE Transactions on Magnetics2005,41,1: | 1 |
| 15 | IAT armature development显示文摘 | MCNAB I R CRAWFORD M T SATAPATHY S S | | 0,,01: | 1 |
| 16 | Synthesis and Characterization of Reversible Chemosensory Polymers: Modulation of Sensitivity through the Attachment of Novel Imidazole Pendants显示文摘 | Satapathy R Padhy H Wu Y-H | 2012 | Chemistry-A European Journal2012,18,16: | 1 |
| 17 | Crack toughness behaviour of multiwaned carbon nanotube (MWNT)/polycarbonate nanocomposites 显示文摘 | Satapathy B K Weidisch R Potschke P | 2005 | Macromol Rapid Comm2005,26,15: | 1 |
| 18 | IAT armature develop- ment显示文摘 | I R MeNab M T Crawford S S Satapathy | 2011 | IE- EE Trans Plas2011,39,1: | 1 |
| 19 | Beneficial effects of tumor necrosis factor-alpha inhibition by pentoxifylline on clinical,biochemical,and metabolic parameters of patients with nonalcoholic steatohepatitis显示文摘 | Satapathy SK Garg S Chauhan R | 2004 | Am J Gastroenterol2004,99,10: | 1 |
| 20 | Viscoelastic properties correlations to morphological and mechanical re- sponse of HDPE/UHMWPE blends 显示文摘 | JAGGI H S SATAPATHY B K RAY A R | 2014 | J Polym Res2014,21,8: | 1 |