|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Primary squamous cell carcinoma of the rectum: An update and implications for treatment显示文摘AIM: To provide an update on the aetiology, pathogenesis, diagnosis, staging and management of rectal squamous cell carcinoma(SCC).METHODS: A systematic review was conducted according to the preferred reporting items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive search of Ovid MEDLINE was performed with the reference list of selected articles reviewed to ensure all relevant publications were captured. The search strategy was limited to the English language, spanning from 1946 to 2015. A qualitative analysis was undertaken examining patient demographics, clinical presentation, diagnosis, staging, treatment and outcome. The quantitaive analysis was limited to data extracted on treatment and outcomes including radiological, clinical and pathological complete response where available. The narrative and quantitative review were synthesised in concert.RESULTS: The search identified 487 articles in total with 79 included in the qualitative review. The quantitative analysis involved 63 articles, consisting of 43 case reports and 20 case series with a total of 142 individual cases. The underlying pathogenesis of rectal SCC while unclear, continues to be defined, with increasing evidence of a metaplasia-dysplasia-carcinoma sequence and a possible role for human papilloma virus in this progression. The presentation is similar to rectal adenocarcinoma, with a diagnosis confirmed by endoscopic biopsy. Many presumed rectal SCC's are in fact an extension of an anal SCC, and cytokeratin markers are a useful adjunct in this distinction. Staging is most accurately reflected by the tumour-nodemetastasis classification for rectal adenocarcinoma. It involves examining locoregional disease by way of magnetic resonance imaging and/or endorectal ultrasound, with systemic spread excluded by way of computed tomography. Positron emission tomography is integral in the workup to exclude an external siteof primary SCC with metastasis to the rectum. While the optimal treatment remains as yet undefined, recent studies have demonstrated a global shift away from surgery towards definitive chemoradiotherapy as primary treatment. Pooled overall survival was calculated to be 86% in patients managed with chemoradiation compared with 48% for those treated traditionally with surgery. Furthermore, local recurrence and metastatic rates were 25% vs 10% and 30% vs 13% for the chemoradiation vs conventional treatment cohorts.CONCLUSION: The changing paradigm in the treatment of rectal SCC holds great promise for improved outcomes in this rare disease. | Glen R Guerra Cherng H Kong Satish K Warrier Andrew C Lynch Alexander G Heriot Samuel Y Ngan | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 5 |
| 2 | Prediction of genetic value for sweet cherry fruit maturity among environments using a 6K SNP array显示文摘The timing of fruit maturity is an important trait in sweet cherry production and breeding.Phenotypic variation for phenology of fruit maturity in sweet cherry appears to be under strong genetic control,but that control might be complicated by phenotypic instability across environments.Although such genotype-by-environment interaction(G×E)is a common phenomenon in crop plants,knowledge about it is lacking for fruit maturity timing and other sweet cherry traits.In this study,1673 genome-wide SNP markers were used to estimate genomic relationships among 597 weakly pedigree-connected individuals evaluated over two seasons at three locations in Europe and one location in the USA,thus sampling eight‘environments’.The combined dataset enabled a single meta-analysis to investigate the environmental stability of genomic predictions.Linkage disequilibrium among marker loci declined rapidly with physical distance,and ordination of the relationship matrix suggested no strong structure among germplasm.The most parsimonious G×E model allowed heterogeneous genetic variance and pairwise covariances among environments.Narrow-sense genomic heritability was very high(0.60–0.83),as was accuracy of predicted breeding values(>0.62).Average correlation of additive effects among environments was high(0.96)and breeding values were highly correlated across locations.Results indicated that genomic models can be used in cherry to accurately predict date of fruit maturity for untested individuals in new environments.Limited G×E for this trait indicated that phenotypes of individuals will be stable across similar environments.Equivalent analyses for other sweet cherry traits,for which multiple years of data are commonly available among breeders and cultivar testers,would be informative for predicting performance of elite selections and cultivars in new environments. | Craig M.Hardner Ben J.Hayes Satish Kumar Stijn Vanderzande Lichun Cai Julia Piaskowski JoséQuero-Garcia JoséAntonio Campoy Teresa Barreneche Daniela Giovannini Alessandro Liverani Gérard Charlot Miguel Villamil-Castro Nnadozie Oraguzie Cameron P.Peace | 2019 | Horticulture Research2019，6，1： | 5 |
| 3 | Fundamental issues related to flow boiling in minichannels and microchannels显示文摘 | Satish G Kandlikar | 2002 | Experimental Thermal and Fluid Science2002，，2： | 2 |
| 4 | Division of flow in short open channel branches 显示文摘 | Ramamurthy A S Satish M G | 1988 | J Hydr Engrg ASCE1988，114，4： | 1 |
| 5 | Facile synthesis and gas sensing properties of nanotriangular tin oxide显示文摘 | RUPALI G DESHMUKH SATISHS | | 0，，28： | 1 |
| 6 | Decidualized endometrial stromal cell derived factors promote trophoblast invasion显示文摘 | Geeta G Pankaj S Satish KG | 2011 | Fertil Steril2011，95，4： | 1 |
| 7 | Continuous flow pho- tocatalytic reactor using ZnO-bentonite nanocomposite for degradation of phenol 显示文摘 | Satish M Rohan L Shailesh G | 2011 | Chemical Engineering Journal2011，172，23： | 1 |
| 8 | Preparation of highly ordered mesoporous AlSBA-15 and its application to isopropylation of m-cresol显示文摘 | SATISH KUMARB G ARIGA K | 2005 | Journal of Molecular Catalysis A:Chemical2005，235，： | 1 |
| 9 | Conductivity studies in some CaO and ZnO doped vanadophosphate glasses 显示文摘 | SUJATHA T KUMARA SATISH SANKARAPPA T DEVIDASA G B HANAGODIMATH S M | 2013 | International Journal of Engineering Research and Applications2013，3，： | 1 |
| 10 | Oxyfunctionalization of cyclohexane catalyzed by oxo-bfidged manganese schiff base complexes 显示文摘 | Pralhad A G Gopal L T Sheo Satish | 1995 | Tetrahedron Lett1995，35，48： | 1 |
| 11 | Fundamental issues related to flow boiling in minichannels and microchannels 显示文摘 | Kandlikar Satish G | 2002 | Experimental Thermal and Fluid Science2002，26，： | 1 |
| 12 | Scale effects on flow boiling heat transfer in microchannels: A fundamental perspective显示文摘 | Satish G Kandlikar | 2010 | International Journal of Thermal Sciences2010，，49： | 1 |
| 13 | Insular carcinoma of the thyroid in a 10-year-old child显示文摘 | RIJHWANI A SATISH G N | 2003 | J Pediatr Surg2003，38，7： | 1 |
| 14 | Solution spinning and characterization of poly (vinyl alcohol)/soybean protein blend fibers显示文摘 | Xiefei Zhang Byung G Min Satish Kumar | 2003 | Journal of Applied Polymer Science2003，90，： | 1 |
| 15 | A roadmap for implementing minichannels in re- frigeration and air-conditioning systems-current status and future direc- tions显示文摘 | Satish G Kandlikar | 2007 | Heat Transfer Engineering2007，28，12： | 1 |
| 16 | A roadmap for implementing minichanne|s in re- frigeration and air-conditioning systems-current status and future direc- tions显示文摘 | Satish G Kandlikar | 2007 | Heat Transfer Engineering2007，28，12： | 1 |
| 17 | Electrical and magnetic properties of nanocrystalline Fe100-xNix alloys 显示文摘 | Satish Vitta Khuntia A Ravikumar G | 2008 | Journal of Magnetism and Magnetic Materials2008，32，： | 1 |
| 18 | Thermal management issues in a PEMFC stack - a brief review of current status 显示文摘 | SATISH G K ZIJIE L | 2009 | Applied Thermal Engineering2009，，29： | 1 |
| 19 | Apical hypertrophic cardiomyopathy in association with Takayasu's arteritis显示文摘 | Satish OS Ravikumar A Koshy G | 2002 | Indian Heart J2002，54，： | 1 |
| 20 | Coolant strategies for BOF steelmaking显示文摘 | Satish Kumar D Prasad G Ghorui P K | 2008 | Ironmaking and Steelmaking2008，5，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员