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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | 在线超临界流体萃取-超高效液相色谱-光电二极管检测器联用分析胡椒粉中的胡椒碱显示文摘本文介绍的联用分析系统是将超临界流体萃取(SFE)系统与超高效液相色谱(UHPLC)系统联用。使用在线SFE-UHPLC系统,可以完成对胡椒粉中胡椒碱成分的高速萃取和分析。整个分析过程包括萃取时间在内只需要7min。将此方法的萃取回收率与其他萃取方法进行比较,SFE方法得到的回收率与其他方法相当。这种在线SFE-UHPLC方法操作简单,分析速度快。这一方法对于分析固体样品中的化合物组分非常有用,可以有效避免繁琐的样品预处理过程。 | Takayuki YAMAGUCHI Kazutoshi KAMEZAWA Keijin IWAYA Yasuyo SATO Toshihiko MIYAJI Masao BOUNOSHITA David J TOGNARELLI Muneo SAITO | 2011 | 生命科学仪器2011，9，2： | 4 |
| 4 | 吸烟状况与急性缺血性脑卒中后功能结局的关系显示文摘吸烟是脑卒中的既定危险因素;然而,脑卒中前吸烟状态是否会影响急性缺血性脑卒中的临床预后尚不确定。该研究旨在阐明吸烟状态与急性缺血性脑卒中后功能预后的关系。研究者获取一项基于日本多中心医院的脑卒中登记资料,调查了2007年7-12月期间住院的10825例急性缺血性脑卒中患者,这些患者在脑卒中发作之前生活能够自理。吸烟状况分为从未吸烟者(不吸烟者),曾经吸烟者和现在吸烟者。临床结局包括3个月时功能转归不良(改良的Rankin量表评分≥2)和功能性依赖(改良的Rankin量表评分2~5)。 | 刘青(译) 刘莉(摘、审校) Matsuo R Ago T Kiyuna F Sato N Nakamura K Kuroda J Wakisaka Y Kitazono T | 2020 | 中华高血压杂志2020，28，2： | 4 |
| 5 | Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin显示文摘 | Sato S Yamate J Saito T | 2002 | Naunyn Schmiedebergs Arch Pharmacol2002，365，： | 2 |
| 6 | Increased expression of Fas antigen on bone marrow CD+34 cells of patients with aplastic anaemia显示文摘 | Maciejewski J P Selleri C Sato T | | 0，，： | 2 |
| 7 | Feasibility of magnetic liposomes as a targeting device for drug 显示文摘 | Kiwada H Sato J Yamada S | 1986 | Chem Pharm Bull1986，34，： | 1 |
| 8 | Effect of cutting edge shape of diamond abrasive grain on ductile mode grinding of optical glass显示文摘 | Tamaki J Sato G Maekawa K | 2005 | Journal of the Japan Society for Abrasive Technology2005，49，6： | 1 |
| 9 | Practical control method for ultra-precision positioning using ballscrew mechanism显示文摘 | Maeda G J Sato K | 2008 | Precision Engineering2008，32，4： | 1 |
| 10 | Growth factor-induced phosphorylation of sterol regulatory element-bind ing proteins inhibits sumoylation, thereby stimulating the ex pression of their target genes,low density lipoprotein uptake, and lipid synthesis显示文摘 | Arito M Horiba T Hachimura S Inoue J Sato R | 2008 | J Biol Chem2008，283，15： | 1 |
| 11 | Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA显示文摘 | MARCHESI J R SATO T A WEIGHTMAN J | 1998 | Applied and Environmental Microbiology1998，64，： | 1 |
| 12 | Effect of folate and mecobalamin on hip fractures in patients with stroke:a randomized controlled trial显示文摘 | Sato Y Honda Y Iwamoto J | 2005 | JAMA2005，293，9： | 1 |
| 13 | A mutual regulation between cell-cell adhesion and N-glycosylation : implication of the bisecting GlcNAc for biological functions 显示文摘 | Gu J Sato Y Kariya Y | 2009 | J Proteome Res2009，8，2： | 1 |
| 14 | Increase pulmonary vascular contraction to serotonin after eardiopulmonary bypass:role of eyclooxygenase显示文摘 | Sato K Li J Metais C | 2000 | J Surg Res2000，90，2： | 1 |
| 15 | Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation显示文摘 | Fukuda MN Sato T Nakayama J | 1995 | Genes Dev1995，9，10： | 1 |
| 16 | Preeclampsia: a microvesicular fat disease of the liver显示文摘 | Minakami H Oka N Sato J | 1988 | Am J Obstet Gynecol1988，159，： | 1 |
| 17 | The effect of supragingival plaque control on the subgingival microbiota in subjects with periodontal disease显示文摘 | Dahlen G Lindhe J Sato K | 1992 | J Clin Periodontol1992，19，： | 1 |
| 18 | Study of Clara cell 16, KL-6, and surfactant protein-D in serum as disease markers in pulmonary sarcoidosis 显示文摘 | Janssen R Sato H Grutters J | 2003 | Chest2003，124，： | 1 |
| 19 | Inflammatory tumor in pancreatic tail induced by endoscopic ablation with cyanoacrylate glue for gastric varices显示文摘 | Sato T Yamazaki K Toyota J | 2004 | J Gastroenterol2004，39，5： | 1 |
| 20 | A method to produce evolving functional connectivity maps during the course of an FMRI experiment using wavelet-based time-varying Granger causality 显示文摘 | Sato J Junior E Takahashi D | 2006 | NeuroImage2006，31，： | 1 |
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