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113篇 您的检索式：作者名="Saul R"

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	题名	作者	年代	出处	被引量
1	Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver显示文摘AIM:To determine if blockade of P-selectin in the isolated blood-perfused cold ex vivo rat liver model protects the liver from ischemia-reperfusion injury. METHODS:The effect of P-selectin blockade was assessed by employing an isolated blood-perfused cold ex vivo rat liver with or without P-selectin antibody treatment before and after 6 h of cold storage in University of Wisconsin solution. RESULTS:In our isolated blood-perfused rat liver model,pre-treatment with P-selectin antibody failed to protect the liver from ischemia-reperfusion injury,as judged by the elevated aspartate aminotransferase activity. In addition,P-selectin antibody treatment did not significantly reduced hepatic polymorphonuclear leukocyte accumulation after 120 min of perfusion. Histological evaluation of liver sections obtained at 120 min of perfusion showed significant oncotic necrosis in liver sections of both ischemic control and P-selectin antibody-treated groups. However,total bile production after 120 min of perfusion was signifi cantly greater in P-selectin antibody-treated livers,compared to control livers. No signifi cant difference in P-selectin and ICAM-1 mRNAs and proteins,GSH,GSSG,and nuclear NF-κB was found between control and P-selectin antibody-treated livers. CONCLUSION:In conclusion,we have shown that blockade of P-selectin alone failed to reduced polymorphonuclear leukocyte accumulation in the liver and protect hepatocytes from ischemia-reperfusion injury in the isolated blood-perfused cold-ex vivo rat liver model.	Samuel Wyllie Neal R Barshes Saul J Karpen John A Goss	2008	World Journal of Gastroenterology2008，14，44：	4
2	Remote organ ischemic preconditioning protect brain from ischemic damage following asphyxial cardiac arrest 显示文摘	Dave KR Saul I Prado R	2006	Neurosci Lett2006，404，12：	1
3	High efficiency direct gene transfer to plants 显示文摘	SHILLITO R D SAUL M W PAZSKOWSKI J	1985	Biotechnology1985，3，：	1
4	Albumin treatment reduces neurological deficit and protects blood-brain barrier integrity after acute intracortical hematoma in the rat显示文摘	Belayev L Saul I Busto R	2005	Stroke2005，36，32：	1
5	Heteromeric assembly of P2X subunits显示文摘	Saul A Hausmann R Kless A	2013	Front Cell Neurosci2013，7，2：	1
6	Tofu and soy drinks cortain phytoes toetrogem显示文摘	DWYER J T GOLDIN B R SAUL N	1994	Journal of the American Dietetic Association1994，94，：	1
7	Seismic images of crust and upper mantle beneath Tibet: Evidence for Eurasian plate subduction显示文摘	Kind R Yuan X Saul J	2002	Science2002，298，：	1
8	Benchmarking of dynamic simulation predictions in two software platforms using an upper limb musculoskeletal model 显示文摘	Saul K R Xiao H Goehler C M	2015	Computer Methods in Biome- chanics & Biomedical Engineering2015，18，13：	1
9	Astrocytes react to oligemia in the forebrain induced by chronic bilateral common carotid artery occlusion in rats 显示文摘	Schmidt-Kastner R Aguirre-Chen C Saul I	2005	Brain Res2005，1052，1：	1
10	Seismic imagnes of crust and upper mantle beneath Tibet: evidence for Asian plate subduction显示文摘	Kind R Yuan X Saul J	2002	Science2002，298，：	1
11	Transient monocular blindness caused by vasospasm显示文摘	Burger S Saul R Selhorst J	1991	N Engl J Med1991，325，12：	1
12	Astrocytes react to oligemia in the forebrain induced by chronic bilateral common carotid artery occlusion in rats 显示文摘	SCHMIDT-KASTNER R AGUIRRE-CHEN C SAUL I	2005	Brain Res2005，1052，1：	1
13	Seismic images of the crust and upper mantle beneath Tibet: Evidence for Eurasian plate subduction显示文摘	King R Yuan X Saul J	2002	Science2002，298，5596：	1
14	Oligonucleotide probe technology as applied to the study of harmful algal blooms显示文摘	Tyrrell J V Bergouist P R Saul D J	1997	New Zealand Journal of Marine and Freshwater Research1997，31，：	1
15	特大跨度的斜拉桥显示文摘	Saul R 林广元	1991	世界桥梁1991，，03：	1
16	&D Evidence from Israel显示文摘	Lach Saul Do Subsidies Stimulate or Displace Private R	2002	(4): 369-3902002，，4：	1
17	Adaptive Subsample Time Delay Estimation Using Lagrange Interpolators显示文摘	Saul R D Dooley S R Nandi A K	1999	IEEE Signal Processing Letters1999，6，3：	1
18	Nmwe growth factor is a potential therapeutic target in breast cancer显示文摘	Adriaenssens E Vanhecke E Saule P Mougel A Page A Romon R	2008	Cancel Res2008，68，2：	1
19	Astrocytes react to oligemia in the forebrain induced by chronic bilateral common carotid artery occlusion in rats 显示文摘	SCHMIDT-KASTBER R AGUIRRE-CHEN C SAUL I	2005	Brain Res2005，1052，1：	1
20	Nonlinear dimcnsionality reduction by locally lin-ear embedding显示文摘	Sam R Saul L	2000	Science2000，290，5500：	1

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