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| 1 | The Simultaneous Repression Of CCR and CAD, Two Enzymes of the Lignin Biosynthetic Pathway, Results in Sterility and Dwarfism in Arabidopsis thaliana显示文摘Cinnamoyl CoA reductase (CCR ) 和 cinnamyl 白酒脱氢酶(CAD ) 催化 monolignol 生合成的最后步骤。在 Arabidopsis,一 CCR 基因(CCR1, At1g15950 ) 并且二 CAD 基因(CAD C At3g19450 和 CAD D At4g34230 ) 涉及这条小径。三倍的恶棍 c 恶棍 d ccr1 变异的、命名 ccc,被获得。这异种显示严格的矮子显型和男绝育。在 ccc 的木质素内容成熟的茎被归结为 50% 野类型的水平。另外,茎木质素结构严重地被影响,在抵抗内部单位的契约和加入由戏剧的丰富出现进象 coniferaldehyde 那样的 monolignol 先锋的聚合物 sinapaldehyde,和 ferulic 酸。男绝育由于在花药内层的木质化的缺乏,它引起花药裂开并且花粉版本的失败。ccc hypolignified 茎积累黄酮醇 glycosides, sinapoyl malate 和 feruloyl malate 的更高的数量,它建议酉分的小径的重定向。因此, CAD 和 CCR 的缺席, monolignol 小径的关键酶,比他们中的每的单个缺席在显型上有更严重的后果。另一 CCR 感应(CCR2, At1g80820 ) 并且另一 CAD (CAD1, At4g39330 ) 不补偿主要 CCR 和 CAD 活动的缺席。CCR 和 CAD 活动的这缺乏不仅影响木质化,而且严重地影响植物的发展。当试着减少植物的木质素内容以便便于 lignocellulose-to-bioethanol 变换过程时,这些后果必须小心地被考虑。 | Johanne Thevenin Brigitte Pollet Bruno Letarnec Luc Saulnier Lionel Gissot Alessandra Maia-Grondard Catherine Lapierre Lise Jouanin | 2011 | Molecular Plant2011，4，1： | 18 |
| 2 | New tools for optimizing fluid resuscitation in acute pancreatitis显示文摘Acute pancreatitis(AP)is a frequent disease with degrees of increasing severity responsible for high morbidity.Despite continuous improvement in care,mortality remains significant.Because hypovolemia,together with microcirculatory dysfunction lead to poor outcome,fluid therapy remains a cornerstone of the supportive treatment.However,poor clinical evidence actually support the aggressive fluid therapy recommended in recent guidelines since available data are controversial.Fluid management remains unclear and leads to current heterogeneous practice.Different strategies may help to improve fluid resuscitation in AP.On one hand,integration of fluid therapy in a global hemodynamic resuscitation has been demonstrated to improve outcomein surgical or septic patients.Tailored fluid administration after early identification of patients with high-risk of poor outcome presenting inadequate tissue oxygenation is a major part of this strategy.On the other hand,new decision parameters have been developed recently to improve safety and efficiency of fluid therapy in critically ill patients.In this review,we propose a personalized strategy integrating these new concepts in the early fluid management of AP.This new approach paves the way to a wide range of clinical studies in the field of AP. | Perrine Bortolotti Fabienne Saulnier Delphine Colling Alban Redheuil Sebastien Preau | 2014 | World Journal of Gastroenterology2014，20，43： | 5 |
| 3 | Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome显示文摘 | Delphine M. Saulnier Kevin Riehle Toni–Ann Mistretta Maria–Alejandra Diaz Debasmita Mandal Sabeen Raza Erica M. Weidler Xiang Qin Cristian Coarfa Aleksandar Milosavljevic Joseph F. Petrosino Sarah Highlander Richard Gibbs Susan V. Lynch Robert J. Shulman | 2011 | Gastroenterology2011，，5： | 4 |
| 4 | Cell wall polysaccharide interactions in maize bran显示文摘 | Saulnier L Marot C Chanliaud E Thibault JF | 1995 | Carbohydr Polymers1995，26，： | 2 |
| 5 | In vitro gastrointestinal digestion study of two wheat cultivars and evaluation of xylanase supplementation显示文摘Background:The filamentous fungus Talaromyces versatilis is known to improve the metabolizable energy of wheatbased poultry diets thanks to its ability to produce a pool of CAZymes and particularly endo-β(1,4)-xylanases.In order to appreciate their in vivo mode of action,the supplementation effect of two of its xylanases,XynD and XynB from families GH10 and GH11 respectively,have been evaluated on two different wheat cultivars Caphorn and Isengrain,which were chosen amongst 6 varieties for their difference in non starch polysaccharides content and arabinoxylan composition.Results:Polysaccharides digestion was followed during 6 h along the digestive tract using the TNO gastrointestinal model-1,to mimic monogastric metabolism.Polysaccharide degradation appeared to occur mainly at the jejunal level and was higher with Isengrain than with Caphorn.For both cultivars,XynD and XynB supplementation increased notably the amount of reducing end sugars into the jejuno-ileal dialysates,which has been confirmed by a valuable increase of the soluble glucose into the jejunal dialysates.Conclusions:The amounts of arabinose and xylose into the dialysates and ileal deliveries increased consequently mainly for Caphorn,suggesting that XynD and XynB supplementation in wheat-based diet could alleviate the anti-nutritional effects of arabinoxylans by limiting the physical entrapment of starch and could increase the available metabolizable energy. | Mickael Lafond Bernard Bouza Sandrine Eyrichine Friedrich Rouffineau Luc Saulnier Thierry Giardina Estelle Bonnin Aurélie Preynat | 2015 | Journal of Animal Science and Biotechnology2015，6，3： | 2 |
| 6 | Post-insertion into lipid nanocapsules (LNCs): From experimental aspects to mechanisms显示文摘 | Perrier T Saulnier P Fouchet F | 2010 | IntJPharm2010，396，12： | 1 |
| 7 | Thermal and enzymatic treatments for the release of free ferulie acid from maize bran 显示文摘 | Saulnier L Marot C Elgorriaga M | 2001 | Carbohydrate Polymers2001，45，3： | 1 |
| 8 | Passive leg raising is predictive of fluid responsiveness in spontaneously breathing patients with severe sepsis or acute pancreatitis显示文摘 | Preau S Saulnier F Dewavrin F | 2010 | Crit Care Med2010，38，3： | 1 |
| 9 | Identification and characterization of CKIP-1,a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2显示文摘 | Bosc DG Graham KC Saulnier RB | | 0，，19： | 1 |
| 10 | Involvement of penaeidins in defense reactions of the shrimp Litopenaeus stylirostris to a pathogenic vibrio显示文摘 | M. Muňoz F. Vandenbulcke J. Garnier Y. Gueguen P. Bulet D. Saulnier E. Bachère | 2004 | Cellular and Molecular Life Sciences (-)2004，，7： | 1 |
| 11 | Esterification of cel lulose-enriched agricultural by-products and characterization of mechanical properties of cellulosic films显示文摘 | Chauvelon G Gergaud N Saulnier L | 2000 | Carbohydrate Poly- mers2000，42，4： | 1 |
| 12 | Passive leg raising is predictive of fluid responsiveness in spontaneously breathing patients with severe sepsis or acute pancreatitis 显示文摘 | Preau S Saulnier F Dewavrin F | 2010 | Crit Care Med2010，38，3： | 1 |
| 13 | Passive leg raising is predictive of fluid responsiveness in spontaneously breathing patients with severe sepsis or acute pancreatitis 显示文摘 | Preau S Saulnier F Dewavrin F | 2010 | Crit Care Med2010，38，3： | 1 |
| 14 | Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome显示文摘 | SAULNIER D M RIEHLE K MISTRETTA T A | 2011 | Gastroenterology2011，141，5： | 1 |
| 15 | Thermal and enzymatic treatment for the release of free ferulic acid from maize bran显示文摘 | SAULNIER L MAROT C ELGORRIAGA M E | 2001 | Carbohydr Polym2001，45，3： | 1 |
| 16 | Effect ofhypoxia stress on the immune response and the resistance tovibriosis of the shrimp Penaeus stylirostris显示文摘 | MOULLAC L Q SOYEZ C SAULNIER D | 1998 | Fish &Shellfish Immunology1998，8，： | 1 |
| 17 | Parameters influencing the stealthiness of colloidal drug delivery systems显示文摘 | Arnaud Vonarbourg Catherine Passirani Patrick Saulnier Jean-Pierre Benoit | 2006 | Biomaterials2006，，24： | 1 |
| 18 | Identification of genesthat are differentially expressed in hemocytes of the pacific blue shrimp(Litopenaeus stylirostris)surviving an infection with Vibrio penaeicida显示文摘 | LORGERIL J D SAULNIER D JANECH M G | 2005 | Physiol Genomics2005，21，2： | 1 |
| 19 | New investigation of the structure of grape arabinogalactan-protein显示文摘 | Saulnier L Brillouet J M | 1992 | Carbohydr Res1992，224，： | 1 |
| 20 | Narrow-band interference excison in spread spectrum systems using transform显示文摘 | MEDLY M J SAULNIER G J | 1997 | IEEE Transactions on Communication1997，45，11： | 1 |
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