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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Respiratory electron transport system (ETS) activities in zooplankton and micronekton of the Indo-Pacific region显示文摘 | SCHALK P H | 1988 | Marine Ecology Progress Series1988，44，1： | 1 |
| 3 | Stress factors that can affect studies of drug metabolish in fish 显示文摘 | Sommer C V Binkowski F P Schalk M A | 1986 | Vet Hum Toxicol1986，28，： | 1 |
| 4 | Brain-computer interfaces (BCIs) :detection instead of classification显示文摘 | Schalk G Brunner P Gerhardt LA | 2008 | J Neurosci Methods2008，167，1： | 1 |
| 5 | Brain-computer Interfaces(BCIs):Detection Instead of Classifica-tion显示文摘 | SCHALK G BRUNNER P GERHARDT L A | | 0，，01： | 1 |
| 6 | Pipe eccentricity measurement using laser triangulation显示文摘 | Schalk P Ofner R O’Leary P | 2006 | Image and Vision Computing2006，25，7： | 1 |
| 7 | Effect of andro-gens on the response to antithymocyte globulin in patients with aplastic anaemia显示文摘 | DIX U SCHALK K P | 1988 | Eur J Haematol1988，40，3： | 1 |
| 8 | Brain-computer interfaces (BCIs):detection instead of classification显示文摘 | Schalk G Brunner P Gerhardt LA | | 0，，01： | 1 |
| 9 | An institu- tional perspective on the employment position of temporary workers in the Netherlands 显示文摘 | DE JONG J P SCHALK R GOESSLING T | 2007 | Relations Industrielles2007，62，3： | 1 |
| 10 | The nutritive value of corn cobs in beef cattle rations显示文摘 | BURROUGHS W GERLAUGH P SCHALK A F | 1945 | Journal of Animal Science1945，，4： | 1 |
| 11 | The nutritive value of corn cobs in beef cattle rations 显示文摘 | BURROUGHS W GERLAUGH P SCHALK A F | 1945 | Journal of Animal Science1945，4，4： | 1 |
| 12 | Noninvasive quantitation of liver iron-overload by magnetic resonance imaging显示文摘 | Kaltwasser J P Gottschalk R Schalk K P | | 0，，3： | 1 |
| 13 | Highly efficient and carcinoma-specific adenviral replication restricted by the EGP-2 promoter显示文摘 | Gommans W M McLaughlin P M Schalk J A | 2007 | J Control Release2007，117，1： | 1 |
| 14 | Braincomputer interfaces (BCIs):Detection instead of classification 显示文摘 | SCHALK G BRUNNER P GERHARDT L A | 2008 | Neuroscience Methods2008，167，1： | 1 |
| 15 | Longitudinal vehicle dynamic control for improved vehicle safety 显示文摘 | Hamersma H A Schalk E P | 2014 | Jour- nal of Terramechanics2014，54，： | 1 |
| 16 | Direct improvement of quality of life in colorectal cancer patients using a tailored pathway with quality of life diagnosis and therapy (DIQOL) : study protocol for a randomised con- trolled trial显示文摘 | Klinkhammer - Schalke M Lindberg P Koller M | 2015 | Trials2015，14，16： | 1 |
| 17 | Potential of nonchemical control strategies for reduction of soil insect damage in sweet-potato显示文摘 | Schalk J M Bohac J R Dukes P D | 1993 | J Am Soc Hortic Sci1993，，118： | 1 |
| 18 | Stress factors that can affect studies of drug metabolism in fish显示文摘 | Sommer C V Binkowsike F P Schalk M A | 1986 | VetHumToxicol1986，，： | 1 |
| 19 | Brain-computer interfaces (BCIs) : Detection instead of classification显示文摘 | Schalk G Brunner P Gerhardt L A | 2008 | Journal of Neuroscience Methods2008，167，： | 1 |
| 20 | Non-invasive quantitation of liver iron-overload by magnetic resonance imaging显示文摘 | Kaltwasser J P Gottschalk R Schalk K P | | 0，，3： | 1 |
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