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141篇 您的检索式:作者名="Schibli"
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1Peptides radiolabeled with Re-186/188 and Tc-99m as potential diagnostic and therapeutic agents显示文摘Small peptide-based compounds have attracted an enormous interest as carrier molecules to selectively de- liver radionuclides to target tissues, sparing critical normal organs. When looking for 'matched pairs' of radionuclides, suitable for radiolabeling of peptides for diagnosis and therapy, technetium and rhenium represent an almost ideal constellation. The important role of technetium-99m and Re-186/188 is based on the decay characteristics, suitable for tumor diagnosis and therapy. Tc-99m and Re-188 are readily available by either a 99Mo/99mTc or the 188W/188Re ra- dionuclide generator system. Furthermore, technetium and rhenium are chemically related and share structural as well as reactive similarities, which prompt an attractive 'matched-pair' situation. This article shows an overview of 99mTc- and 186/188Re-radiolabeled peptides that have been tested for their potential use as imaging and therapeutic agents in oncological diseases.E. GARCíA-GARAYOA R. SCHIBLI P.A. SCHUBIGER 2007Nuclear Science and Techniques2007,18,2:5
2Towards a structure-function analysis of bovine lactoferricin and related tryptophan and argini-necontaining peptides 显示文摘Vogel H J Schibli D J Jing W G 2002Biochemistry and Cell Biology2002,80,1:1
3^99Tc^m-Labeling and in Vivo Studies of a Bombesin Analogue With a Novel Water-Soluble Dithiadiphosphine-Based Bifunctional Chelating Agent显示文摘KARRA SR SCHIBLI R GALI H 1999Bioconjug Chem1999,10,2:1
4Influence of the Denticity of Ligand Systems on the in Vitro and in Vivo Behavior of 99Tcm (Ⅰ)-Tricarbonyl Complexes:a Hint for the Future Functionalization of Biomolecules显示文摘Schibli R La Bella R Alberto R 2000Bioconjug Chem2000,11,:1
5Steps Toward High Specific Activity Labeling of Biomolecules for the Rapeutic Application:Preparation of Precursor + and Synthesis of Tailor-Made Bifunctional Ligand Systems显示文摘Schibli R Schwarzbach R Alberto R 2002Bioconjug Chem2002,13,4:1
6The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus显示文摘Schibli D J Hunter HN Aseyev V Starner TD Wiencek JM Mc Cray PB Jr Tack BF Vogel HJ 0,,10:1
7A novel organometallic aqua complex of technetium for the labeling of biomolecules : synthesis of + from - in aqueous solution and itsreaction with a bifunctional ligand 显示文摘Alberto R Schibli R Egli A 1998J Am Chem Soc1998,120,:1
8Tryptophan-rich antimicrobial peptides:Comparative properties and membrane interactions显示文摘Schibli D J Ep R F Vogel H J 0,,05:1
9The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus显示文摘 Hunter HN Aseyev V 2002J Biol Chem2002,277,10:1
10Towards a structure-function analysis of bovine lactoferricin and related trypotophan and arginine containing peptides显示文摘Vogel H J Schibli D J Jing W 2002Biochem2002,80,:1
11Type of CFTR Mutation Determines Risk of Pancreatitis in Patients With Cystic Fibrosis显示文摘Chee Y. Ooi Ruslan Dorfman Marco Cipolli Tanja Gonska Carlo Castellani Katherine Keenan Steven D. Freedman Julian Zielenski Yves Berthiaume Mary Corey Susanne Schibli Elizabeth Tullis Peter R. Durie 2011Gastroenterology2011,,1:1
12查看详情显示文摘Lee C C Suzuki S Xie W Schibli T R 0,,:1
13Steps toward high specific activity labeling of biomolecules for therapeutic application : Preparation of precursor ( + ) and synthesis of tailor-made bifunctional ligand systems 显示文摘Schibli R Schwarzbach R Alberto R 2002Bioconjugate Chemistry2002,13,4:1
14Toward single-cycle laser systems 显示文摘SCHIBLI T R KUZUCU O KIM J W 2003IEEE J Select Topics Quantmn Electron2003,9,4:1
15A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules:Synthesis of+ From-in Aqueous Solution and Its Reaction With a Bifunctional Ligand显示文摘Alberto R Schibli R Egli A 1998J Am Chem Soc1998,120,31:1
16A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of ^+ From in Aqueous Solution and Its Reaction With a Bifunctional Ligand显示文摘Alberto R Schibli R Egli A 1998J Am Chem Soc1998,120,:1
17Current Use and Future Potential of Organometallic Radiopharmaceuticals显示文摘Schibli R Schubiger P A 2002EurJ Nucl Med2002,29,:1
18The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of h BD-3 against staphylococcus aureus显示文摘Schibli DJ Huner HN Aseyev V 2002Biol Chem2002,277,10:1
19A three-phase multilevel converter for high-power induction motors显示文摘Schibli N P Tung Nguyen Rufer A C 1998IEEE Trans on PE1998,13,5:1
20Tryptophan-rich antimicrobial peptides:comparative properties and membrane interactions显示文摘Schibli DJ Epand RE Vogel HJ 2002Biochem Cell Biol2002,80,5:1
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