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| 1 | Supportive angiogenic and osteogenic differentiation of mesenchymal stromal cells and endothelial cells in monolayer and co-cultures显示文摘Sites of implantation with compromised biology may be unable to achieve the required level of angiogenic and osteogenic regeneration. The specific function and contribution of different cell types to the formation of prevascularized, osteogenic networks in co-culture remains unclear. To determine how bone marrow-derived mesenchymal stromal cells(BMSCs) and endothelial cells(ECs) contribute to cellular proangiogenic differentiation, we analysed the differentiation of BMSCs and ECs in standardized monolayer, Transwell and co-cultures. BMSCs were derived from the iliac bone marrow of five patients,characterized and differentiated in standardized monolayers, permeable Transwells and co-cultures with human umbilical vein ECs(HUVECs). The expression levels of CD31, von Willebrand factor, osteonectin(ON) and Runx2 were assessed by quantitative reverse transcriptase polymerase chain reaction. The protein expression of alkaline phosphatase, ON and CD31 was demonstrated via histochemical and immunofluorescence analysis. The results showed that BMSCs and HUVECs were able to retain their lineage-specific osteogenic and angiogenic differentiation in direct and indirect co-cultures. In addition, BMSCs demonstrated a supportive expression of angiogenic function in co-culture, while HUVEC was able to improve the expression of osteogenic marker molecules in BMSCs. | Florian Bohrnsen Henning Schliephake | 2016 | International Journal of Oral Science2016，8，4： | 3 |
| 2 | Efficacy and Safety of Great Saphenous Vein Sclerotherapy Using Standardised Polidocanol Foam (ESAF): A Randomised Controlled Multicentre Clinical Trial显示文摘 | E. Rabe J. Otto D. Schliephake F. Pannier | 2007 | European Journal of Vascular & Endovascular Surgery2007，，2： | 2 |
| 3 | Guided bone regeneration around endosseous implants using a resorbable membrane vs a PTFE membrane显示文摘 | Schliephake H | 2000 | Clin Oral Implants Res2000，11，： | 1 |
| 4 | Mechanical anchorage and peri-implant bone formation of surface-modified zirconia in minipigs显示文摘 | Schliephake H Hefti T Schlottig F | | 0，，09： | 1 |
| 5 | Phenolic substrates for fluorometric detection of laccase activity显示文摘 | Lonergan G Mew E Schliephake K | 1997 | FEMS Microbiol Lett1997，153，2： | 1 |
| 6 | A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications显示文摘 | Hutmacher D Hurzeler MB Schliephake H | 1996 | Int J Oral Max Impl1996，11，1： | 1 |
| 7 | Slress doses of hydrocortisone in septic shock: beneficial effects on opsonization-dependent neutrophil functions显示文摘 | Kaufmann I Briegel J Schliephake F | 2008 | Intensive Care Med2008，34，2： | 1 |
| 8 | Efficacy and safety of great sa- phenous vein sclerotherapy using standardized polidocanol foam (ES- AF) :a randomised controlled muhicentre clinical trial显示文摘 | Rabe E Otto J Schliephake D | 2008 | Eur J Vasc Endovasc Surg2008，35，2： | 1 |
| 9 | Enhancement of bone ingrowth into a porous hydroxyapatite - matrix using a resorbale polylactic memebrane:an experimental pilot study 显示文摘 | Schliephake H Neukan FW Hutamcher D | 1994 | J Oral maxillofac surg1994，52，1： | 1 |
| 10 | Use of cultivated osteoprogenitor cecls to increase bore formation a in segmental mandibulardefects:anexpenmental pilot study in sheep显示文摘 | Schliephake H Knebel JW Aufderheide M | | 0，，06： | 1 |
| 11 | Osseointegration of endodontic endosseous cones:zirconium oxide vs titanium显示文摘 | Schultze Mosgau S Schliephake H Radespiel Troger M | 2000 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2000，89，1： | 1 |
| 12 | Use of amineratized collagen membrane to enhance repair of calvarial defects in rats 显示文摘 | Schliephake H Tavassol F Gelinsky M | 2004 | Clin Oral Impl Res2004，2004，： | 1 |
| 13 | Use of culhivated osteoprogenitor cells to increase bone formation in segmental mandibular defects:an experimental pilot study in sheep显示文摘 | Schliephake H Knebel J W Aufderheide M | 2001 | Int J Oral Maxillofac Surg2001，30，： | 1 |
| 14 | Craniofacial distraction esteogenesis: a review of the literature: Part 1: clinical studies显示文摘 | Swennen G Schliephake H Dempf R | 2001 | J Oral Maxillofac Surg2001，30，2： | 1 |
| 15 | Bone growth factors in maxillofacial skeletal reconstruction显示文摘 | Schliephake H | 2002 | Int J Oral Maxillofac Surg2002，31，5： | 1 |
| 16 | Efficacy and safety of great sa- phenous vein sclerotherapy using standardised polidocanol foam (ESAF):a randomised controlled muhieentre clinical trial 显示文摘 | Rabe E Otto J Schliephake D | 2008 | Eur J Vase Endovasc Surg2008，35，2： | 1 |
| 17 | Mandibular bone repair by implantation of rhBMP-2 in a slow release cartier of polylactic acid-An experimental study in rats显示文摘 | Schliephake H Weich HA Dullin C | 2008 | Biomaterials2008，29，1： | 1 |
| 18 | Membrane connexin 43 acts as an independent prognostic marker in oralsquamous cell carcinoma显示文摘 | Phillipp Brockmeyer Klaus Jung Christina Perske Henning Schliephake Bernhard Hemmerlein | 2014 | International Journal of Oncology2014，，1： | 1 |
| 19 | Incidence and regeneration time of disorders of the inferior alveolar nerve in osteosynthesis of mandibular fractures--a prospective clinical study显示文摘 | Schultze-Mosgau S Neukam FW Schliephake H | 1996 | Fortschr Kiefer Gesichtschir1996，41，： | 1 |
| 20 | Comparison of the late results of mandibular reconstruction using nonvascularized or vascularized grafts and dental implants 显示文摘 | SCHLIEPHAKE H SCHMELZEISEN R HUSSTED H | 1999 | J Oral Maxillofac Surg1999，57，8： | 1 |
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