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69篇 您的检索式:作者名="Schubiger"
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1Peptides radiolabeled with Re-186/188 and Tc-99m as potential diagnostic and therapeutic agents显示文摘Small peptide-based compounds have attracted an enormous interest as carrier molecules to selectively de- liver radionuclides to target tissues, sparing critical normal organs. When looking for 'matched pairs' of radionuclides, suitable for radiolabeling of peptides for diagnosis and therapy, technetium and rhenium represent an almost ideal constellation. The important role of technetium-99m and Re-186/188 is based on the decay characteristics, suitable for tumor diagnosis and therapy. Tc-99m and Re-188 are readily available by either a 99Mo/99mTc or the 188W/188Re ra- dionuclide generator system. Furthermore, technetium and rhenium are chemically related and share structural as well as reactive similarities, which prompt an attractive 'matched-pair' situation. This article shows an overview of 99mTc- and 186/188Re-radiolabeled peptides that have been tested for their potential use as imaging and therapeutic agents in oncological diseases.E. GARCíA-GARAYOA R. SCHIBLI P.A. SCHUBIGER 2007Nuclear Science and Techniques2007,18,2:5
2Oral vitamina K1 prophylaxis for newborns with a new mixed - micellar preporation of phylloquinone: 3 years experience in Switzenland显示文摘Schubiger G Stocker C Banzigero K 1999Eur J Pediatr1999,158,7:1
3Isoform spe-cific control of gune activity in vivo by the Drosophi-la ecdysone receptor显示文摘Schubiger M Tomita S Suns C et a1 0,,08:1
4RulBbildung und Oxidation bei der dieselmotorischen Verbrennung显示文摘Schubiger R A Boulouchous K Eberle M K 2002MTZ2002,,5:1
5Stem cell plasticity in mammals and transdetermination in Drosophila显示文摘Wei G Schubiger G Harder F 2000Stem Cells2000,18,6:1
6Stem cell plasticity in mammals and transdetermination in Drosophila: common themes显示文摘WEI G SCHUBIGER G HARDER F 2000Stem Cells2000,18,6:1
7Stem cell plasticity in mammals and transdetermination in Drosophila:common themes?显示文摘WEI G SCHUBIGER G HARDER F 2000Stem Cells2000,18,6:1
8A distributedjavaspace implementation for harness显示文摘Mauro Migliardi Simon Schubiger Vaidy Sunderam 2000Academic Press2000,,60:1
9Current Use and Future Potential of Organometallic Radiopharmaceuticals显示文摘Schibli R Schubiger P A 2002EurJ Nucl Med2002,29,:1
10Assessment of hypoxia and perfusion in human brain tumor using PET with 18F-fluoromisonidazole and 150-H20显示文摘 ROELCKE U SCHUBIGER PA 2004Nucl Med2004,45,11:1
11Assessment of the binding properties of Granuloszint显示文摘P. A. Schubiger P. H. Hasler I. Novak-Hofer P. Bl?uenstein 1989European Journal of Nuclear Medicine1989,,9:1
12Current use and future potential of organometallic radiopharmaceuticals 显示文摘Schibli R and Schubiger PA 2002Eur J Nucl Med Mol Imaging2002,29,11:1
13Copper-67 as a therapeutic nuclide for radioimmunotherapy显示文摘Novak-Hofer I Schubiger P A 2002Eur J Nucl Med Mol Imaging2002,29,:1
14FirstApplication of fac-+ in Bioorganometallic Chemistry: Design, Structure, and in Vitro Affinity of a 5-HT1A Receptor Lig- and Labeled with 99Tc 显示文摘Alberto R Schibli R Schubiger AP 1999Am Chem Soc1999,121,60:1
15How an actin network might cause fountain streaming and nuclear migration in the syncytial Drosophila embryo显示文摘von Dassow G Schubiger G 0,,06:1
16Synthesis and in Vitroin Vivo Evaluation of Novel 99mTc ( CO )3-Folates 显示文摘Muller C Schubiger P A Schibli R 2006Bioconjugate Chem2006,17,3:1
17Transdetermination in drosophila imaginal discs:a model for understanding pluripotency and selector gene maintenance显示文摘Maves L Schubiger G 2003Curr Opin Genet Dev2003,13,5:1
18Prevention of vitamin K deficiency bleeding: efficacy of different multiple oral dose schedules of vitamin K显示文摘M. Cornelissen R. von Kries P. Loughnan G. Schubiger 1997European Journal of Pediatrics1997,,2:1
19Computed tomography in cerebral aneurysms with special emphasis on giant intracranial aneurysms显示文摘Schubiger O Valavanis A Hayek J 1980J Comput Assist Tomogr1980,4,1:1
20First application of fac-^+ in bioorganometallic chemistry: design, structure, and in vitro affinity of a 5- HT1A receptor ligand labeled with ^99mTc 显示文摘Alberto R Schibli R Schubiger A P 1999J Am Chem Soc1999,121,25:1
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