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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | Islet inflammation in Type 2 diabetes: from metabolic stress to therapy显示文摘 | Donath MY Schumann DM Faulenbach M | 2008 | Diabetes Care2008，31，： | 1 |
| 3 | Establishinga reference system in clinical enzymology显示文摘 | Panteghini M Ceriotti F Schumann G | 2001 | Clin ChemLab Med2001，39，9： | 1 |
| 4 | Islet inflammation in type 2 diabetes: from metabolic stress to therapy显示文摘 | Donath MY Schumann DM Faulenbach M | 2008 | Diabetes Care2008，31，2： | 1 |
| 5 | The nurse competence in aging initiative: encouraging expertise in the care of older adults显示文摘 | Stierle L J Mezey M Schumann M J | 2006 | Am J Nurs2006，106，9： | 1 |
| 6 | Preparation of 26A1, SgNi, 44Ti, 3Mn and 6Fe from a proton ir- radiated copper beam dump显示文摘 | AYRANOV M SCHUMANN D | 2010 | Journal of Radio- analytical and Nuclear Chemistry2010，286，3： | 1 |
| 7 | Nanocelluloses as innovative polymers in research and application显示文摘 | Klemm D Schumann D Kramer F He(B)ler N Hornung M Schmauder H P Marsch S | | 0，，09： | 1 |
| 8 | In Vivo Effects of the Anti-Interleukin-6 Receptor Inhibitor Tocilizumab on the B Cell Compartment显示文摘 | Roll P Muhammad K Schumann M | 2011 | Arthritis Rheum2011，63，： | 1 |
| 9 | Spatial characterization of bark beetle infestations by a multidate synergy of SPOT and Landsat imagery显示文摘 | Latifi H Schumann B Kautz M | 2014 | Environmental Monitoring and Assessment2014，186，1： | 1 |
| 10 | Construction and amplication of epitope and green fluorescent protein-tagging integration vectors for Bacillus subtilis 显示文摘 | Marcus K Wiegert M T Schumann W | 2002 | Apple Environ Microbiol2002，68，： | 1 |
| 11 | 17β-estradiol prevents programmed cell death in cardiac myocytes显示文摘 | Pelzer T Schumann M Nenmann M | 2000 | Biochem and Biophys Res Commun2000，268，1： | 1 |
| 12 | Soil moisture estimation with ERS- 1 SAR data in the East German Loess soil area显示文摘 | Weimann A M Von Schonermark Schumann A | 1998 | Int J Remote Sensing1998，19，2： | 1 |
| 13 | RF positivity has substantial influence on the peripheral memory B-cell compartment and its modulation by TNF inhibition显示文摘 | Roll P Muhammad K Schumann M | 2012 | Scand J Rheumatol2012，41，3： | 1 |
| 14 | Cryorecanalization:a new approach for the immediate management of acute air- way obstruction显示文摘 | Hetzel M Hetzel J Schumann C | 2004 | The Journal of Thoracic and Cardiovascu- lar Surgery2004，127，5： | 1 |
| 15 | Influence of Heat Input and Travel Speed on Mierostructure and Mechanical Properties of Double Tandem Submerged Arc High Strength Low Alloy Steel Weldments 显示文摘 | Viano D M Ahmed N U Schumann G O | 2000 | Science and Technology of Welding and Joining2000，5，1： | 1 |
| 16 | Endobronebia/ tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis 显示文摘 | Schumann C Hetzel M Babiak AJ | 2010 | J Thorac Cardiovasc Surg2010，139，4： | 1 |
| 17 | Manage- ment of ranula: 9 years' clinical experience in pediatric and adult patients 显示文摘 | Sigismund P E Bozzato A Schumann M | 2013 | J Oral Maxillofac Surg2013，71，3： | 1 |
| 18 | A flexible approach for visual data mining 显示文摘 | Kreuseler M Schumann H | 2002 | IEEE Trans on Visualization and Computer Graphics2002，8，1： | 1 |
| 19 | Management of Ranula: 9 Yearsj Clinical Experience in Pediatric and Adult Patients 显示文摘 | Sigismund PE Bozzato A Schumann M | 2012 | J Oral Maxillofac Surg2012，25，： | 1 |
| 20 | Potential role of tissue transglutaminase in glaucoma filtering surgery 显示文摘 | Priglinger SG Alge CS Kook D Thiel M Schumann R Eibl K | 2005 | Invest Ophthalmol Vis Sci2005，47，9： | 1 |
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