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| 1 | Diagnosis and surgical management of breast cancer metastatic to the spine显示文摘Breast cancer is the most common malignancy and the second leading cause of death in Western women. Breast cancer most commonly metastasizes to the bone and has a particular affinity with the spine, accounting for 2/3 of osseous metastases discovered. With significant improvements in cancer therapies, the number of patients at risk for symptomatic spinal metastases is likely to increase. Patients may suffer from intractable pain and neurological dysfunction, negatively influencing their quality of life. Timely diagnosis of patients is crucial and has been aided by several breakthrough advances in imaging techniques which aid in detection, staging, and follow-up of bone metastases. Breast metastases are usually responsive to hormonal therapy and pharmacologic interventions, but skeletal metastases often require surgical intervention. The treatments are palliative but goals include the preserving or restoring neurologic function, ensuring spinal stability, and relieving pain. Advances in surgical techniques and instrumentation have allowed more effective decompres-sion and stabilization of the spine, and with the support of recent evidence the trend has shifted towards using more advanced surgical options in appropriately selected patients. In this review, the clinical presentation, diagnosis, patient selection, and surgical management of breast cancer metastatic to the spine are discussed. | Derek G Ju Alp Yurter Ziya L Gokaslan Daniel M Sciubba | 2014 | World Journal of Clinical Oncology2014，5，3： | 4 |
| 2 | Diagnosis and management of metastatic spine disease 显示文摘 | Sciubba DM Petteys R J Dekutoski MB | 2010 | J Neurosurg Spine2010，13，1： | 1 |
| 3 | An unusual case of spinal column metastasis after orthotopic transplantation for cardiac sarcoma显示文摘 | McLoughlin GS Sciubba DM Ali SK | | 0，，04： | 1 |
| 4 | Accuracy of free-hand placement of thoracic pedicle screws in adolescent idiopathic scoliosis:how much of a difference does surgeon experience make显示文摘 | Samdani AF Ranade A Sciubba DM | | 0，，： | 1 |
| 5 | Diagnosis and management of metastatic cervical spine tumors 显示文摘 | Molina CA Gokaslan ZL Sciubba DM | 2012 | Orthop Clin North Am2012，43，1： | 1 |
| 6 | Long-term clinical outcomes following en bloc resections for sacral chordomas and ehondrosarcomas: a series of twenty consecutive patients 显示文摘 | Hsieh PC Xu R Sciubba DM | 2009 | Spine2009，34，20： | 1 |
| 7 | Oral complications of radiotherapy 显示文摘 | Sciubba J J Goldenberg D | 2006 | Lancet Oncol2006，7，2： | 1 |
| 8 | Orofacial granulomatosis: presentation,pathology and management of 13 cases 显示文摘 | Sciubba JJ Said-A1-Naief N | 2003 | J Oral Pathol Med2003，32，10： | 1 |
| 9 | Evaluation of factors associated with postoperative infection following sacral tumor resection 显示文摘 | Sciubba DM Nelson C Gok B | 2008 | J Neurosurg Spine2008，9，6： | 1 |
| 10 | Accuracy of free-hand placement of thoracic pedicle screws in adolescent idiopathic scoliosis:how much of a difference does surgeon experience make显示文摘 | Samdani AF Ranade A Sciubba DM | | 0，，01： | 1 |
| 11 | En bloc total sacrectomy performed in a single stage through a posterior approach显示文摘 | McLoughlin GS Sciubba DM Suk I | 2008 | Neurosurgery2008，63，11： | 1 |
| 12 | Automatic diagnostics and prognostics of energy conversion processes via knowledge based systems显示文摘 | Biagetti T Sciubba E | 2004 | Energy2004，29，1215： | 1 |
| 13 | Peripheral epithelial odontogenic tumors: a review 显示文摘 | Buchner A Sciubba JJ | 1987 | Oral Surg Oral Med Oral Pathol1987，63，6： | 1 |
| 14 | Effect of antibiotic-im- pregnated shunt catheters in decreasing the incidence of shunt infec- tion in the treatment of hydrocephalus 显示文摘 | Sciubba DM Smart RaM McGirt M J | 2005 | J Neumsurg2005，103，2： | 1 |
| 15 | Acute intracranial subdural hematoma fol owing a lumbar CSF leak caused by spine surgery显示文摘 | Sciubba DM Kretzer RM Wang PP | | 0，，1976： | 1 |
| 16 | Application of the entropy generation minimization method to a solar heat exchanger : A pseudo- optimization local entropy generation maps 显示文摘 | GIANGASPERO G SCIUBBA E | 2013 | Energy2013，58，： | 1 |
| 17 | En bloc excisions of chordomas in the cervical spine: review of five consecutive cases with more than 4-year follow-up 显示文摘 | Hsieh PC Gallia GL Sciubba DM | 2011 | Spine2011，36，24： | 1 |
| 18 | Which daily functions are most affected by stiffness following total lumbar fusion: compari- son of upper thoracic and thoracolumbar proximal endpoints显示文摘 | Sciubba DM Scheer JK Smith JS | 2014 | Spine2014，40，17： | 1 |
| 19 | Factors associated with cervical instability requiring fusion after cervical laminectomy for intradural tumor resection显示文摘 | Sciubba DM Chaichana KL Woodworth GF | 2008 | J Neurosurg Spine2008，8，5： | 1 |
| 20 | En bloc total sacrectomy performed in a single stage through a posterior approach显示文摘 | Mcloughlin GS Sciubba DM Suk I | | 0，，1： | 1 |
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