|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diabetic retinopathy and age-related macular degeneration: a survey of pharmacoutilization and cost in Calabria, Italy显示文摘The aged population is constantly growing, thus fostering an increase in age-dependent diseases. Among these, diabetic retinopathy (DR) along with age-related macular degeneration entails progressive vision loss. Since such conditions are associated with the proliferation of novel vessels, their pharmacotherapeutic management consists of the intravitreal injection of anti-vascular endothelial growth factor drugs, able to hinder the driving of vascular proliferation prompted by vascular endothelial growth factor. The humanized anti-vascular endothelial growth factor monoclonal antibody ranibizumab provided evidence for efficacy in several trials, hence earning approval by the US Food and Drug Administration for therapeutic use in all the stages of DR. Due to the lack of epidemiologic and pharmacoeconomic evaluation in the local Calabria Region context, the present retrospective observational study focused on prevalence of DR and age-related macular degeneration, treatment and cost of therapy with ranibizumab in 870 patients arriving to clinical observation at the 'Mater Domini” University Hospital in Calabria, Italy from January 2014 to June 2017. Data were extracted from the database of ophthalmology ward and subjected to statistical analysis. The results suggest that the most frequent retinal diseases are age-related macular degeneration and DR and that the use of ranibizumab has been decreasing over the 4-year study period together with the associated cost per patient which was similar for both disorders. Therefore, appropriateness of treatment with drugs other than ranibizumab needs to be assessed in this setting and deep monitoring of pharmacologic treatment for retinal diseases is necessary to prevent or delay visual acuity decrease and complete vision loss. Study procedures were performed in accordance with the 'Mater Domini” University Hospital ethical standards of the responsible committee on human experimentation. | Damiana Scuteri Ada Vero Mariacristina Zito Maria Diana Naturale Giacinto Bagetta Carlo Nucci Paolo Tonin Maria Tiziana Corasaniti | 2019 | Neural Regeneration Research2019，14，8： | 3 |
| 2 | Aortic stiffness and hypotension episodes are associated with impaired cognitive function in older subjects with subjective complaints of memory loss 显示文摘 | Scuteri A Tesauro M Guglini L | 2013 | Int J Cardiol2013，169，5： | 1 |
| 3 | Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association显示文摘 | Gorelick PB Scuteri A Black SE | 2011 | Stroke2011，42，9： | 1 |
| 4 | Relevance of echocardio-graphic evaluation of right ventricular function in patients undergoing cardiac resynchronization therapy显示文摘 | Scuteri L Rordorf R Marsan NA | 2009 | PACE2009，32，8： | 1 |
| 5 | Pulse pressure is inversely related to aortic root diameter implications for the pathogenesis of systolic hypertension 显示文摘 | Farasat SM Morrell CH Scuteri A | 2008 | Hypertension2008，51，2： | 1 |
| 6 | Impact of fasting glycemia and regional cerebral perfusion in diabetic subjects: a study with technetium-99m-ethyl cysteinate dimer single photon emission computed tomography显示文摘 | Cosentino F Battista R Scuteri A | 2009 | Stroke2009，40，1： | 1 |
| 7 | Pulse wave velocity is anindependent predictor of the longitudinal increase in systolic bloodpressure and of incident hypertension in the BaltimoreLongitudinal Study of Aging显示文摘 | Najjar SS Scuteri A Shetty V | | 0，，14： | 1 |
| 8 | Metabolic Syndrome amplifies the age-associated increases in vascular thickness and stiffness 显示文摘 | SCUTERI A NAJJAR S S MULLER D C | 2004 | J Am Coll Cardiol2004，43，8： | 1 |
| 9 | Arterial aging: Is it an immutable cardiovascular risk factor? 显示文摘 | Najjar SS Scuteri A Lakatta EG | 2005 | Hypertension2005，46，3： | 1 |
| 10 | Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association显示文摘 | Gorelick PB Scuteri A Black SE | 2011 | Stroke2011，42，9： | 1 |
| 11 | Arterial aging: is it an immutable cardiovascular risk factor?显示文摘 | Najjar SS Scuteri A Lakatta EG | 2005 | Hypertension2005，46，3： | 1 |
| 12 | Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging显示文摘 | Najjar SS Scuteri A Shetty V | 2008 | J Am Coil Car- diol2008，51，14： | 1 |
| 13 | Is apoE4 allele an independent predictor of coronary events?显示文摘 | Scuteri A Bos AJ Znderman AB | 2001 | Am J Med2001，110，1： | 1 |
| 14 | Depression, hypertension, and comorbidity: disentangling their specific effect on disability and cognitive impairment in older subjects 显示文摘 | Scuteri A Spazzafumo L Cipriani L | 2011 | Arch Gerontol Geriatr2011，52，： | 1 |
| 15 | COL4A1 is associated with arterial stiffiless by genome wide association scan 显示文摘 | Tarasov KV Sanna S Scuteri A | 2009 | Circ Cardiovasc Genet2009，2，2： | 1 |
| 16 | Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness 显示文摘 | SCUTERI A NAJJAR SS MULLER DC | 2004 | J Am Coll Cardiol2004，43，8： | 1 |
| 17 | Metabolic syndrome amplifies the age- associated increases in vascular thickness and stiffness 显示文摘 | Scuteri A Najjar SS Muller DC | 2004 | J Am Coil Cardiol2004，43，： | 1 |
| 18 | MAPKs as mediators of cell fate determination:an approach to neurodegenerative diseases 显示文摘 | Miloso M Scuteri A Foudah D | 2008 | Curr Med Chem2008，15，6： | 1 |
| 19 | The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the cardiovascular health study 显示文摘 | Scuteri A Najjar SS Morroll CH | 2005 | Diabetes Care2005，28，4： | 1 |
| 20 | Mesenchymal stem cells neuronal differentiation ability:a real perspective for nervous system repair显示文摘 | Scuteri A Miloso M Foudah D | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员