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| 1 | Asymptomatic dogs are highly competent to transmit Leishmania ( Leishmania ) infantum chagasi to the natural vector显示文摘 | Márcia Dalastra Laurenti Claudio Nazaretian Rossi Vania Lúcia Ribeiro da Matta Thaise Yumie Tomokane Carlos Eduardo Pereira Corbett Nágila Francinete Costa Secundino Paulo Filemon Paulocci Pimenta Mary Marcondes | 2013 | Veterinary Parasitology2013，，： | 1 |
| 2 | A Case Report of a Pyo-genic Liver Abscess Caused by Fusobacterium Nucleatumin a PatientWith Autosomal Dominant Polycystic KidneyDisease Undergoing Hemodialysis显示文摘 | Secundino C Carmen NT Jose ML | 2008 | Ther Apher Dial2008，12，1： | 1 |
| 3 | Refractive errors among children, adolescents and adults attending eye clinics in Mexico显示文摘AIM:To assess the proportion of refractive errors in the Mexican population that visited primary care optometry clinics in fourteen states of Mexico. METHODS:Refractive data from 676 856 patients aged 6 to 90 y were collected from optometry clinics in fourteen states of Mexico between 2014 and 2015. The refractive errors were classified by the spherical equivalent(SE), as follows:sphere+? cylinder. Myopia(SE>-0.50 D), hyperopia(SE>+0.50 D), emmetropia(-0.50≤SE≤+0.50), and astigmatism alone(cylinder≥-0.25 D). A negative cylinder was selected as a notation.RESULTS:The proportion(95% confidence interval) among all of the subjects was hyperopia 21.0%(20.9-21.0), emmetropia 40.7%(40.5-40.8), myopia 24.8%(24.7-24.9) and astigmatism alone 13.5%(13.4-13.5). Myopia was the most common refractive error and frequency seemed to increase among the young population(10 to 29 years old), however, hyperopia increased among the aging population(40 to 79 years old), and astigmatism alone showed a decreasing trend with age(6 to 90y; from 19.7% to 10.8%). There was a relationship between age and all refractive errors(approximately 60%, aged 50 and older). The proportion of any clinically important refractive error was higher in males(61.2%) than in females(58.3%; P<0.0001). From fourteen states that collected information, the proportion of refractive error showed variability in different geographical areas of Mexico.CONCLUSION:Myopia is the most common refractive error in the population studied. This study provides the first data on refractive error in Mexico. Further programs and studies must be developed to address the refractive errors needs of the Mexican population. | Francisco Gomez-Salazar Abraham Campos-Romero Humberto Gomez-Campana Cinthia Cruz-Zamudio Mariano Chaidez-Felix Nidia Leon-Sicairos Jorge Velazquez-Roman Hector Flores-Villasenor Secundino Muro-Amador Alma Marlene Guadron-Llanos Javier J.Martinez-Garcia Joel Murillo-Llanes Jaime Sanchez-Cuen Alejando Llausas-Vargas Gerardo Alapizco-Castro Ana Irineo-Cabrales Enrique Graue-Hernandez Tito Ramirez-Luquin Adrian Canizalez-Roman | 2017 | International Journal of Ophthalmology(English edition)2017，10，5： | 1 |
| 4 | Short t erm hydroelectric scheduling combining network flow and interior point approaehes 显示文摘 | AURELIO RL O SECUNDINO S LEONARDO N | 2005 | International Journal of Electrical Power and Energy Systems2005，27，2： | 1 |
| 5 | Salmonella porins induce a sustained, lifelong specific bactericidal antibody memory response 显示文摘 | SECUNDINO I LOPEZ-MACIAS C CERVANTES-BARRAGAN L | 2006 | Immunology2006，117，1： | 1 |
| 6 | Salmonella porins induce a sustained, lifelong specific bacteri- cidal antibody memory response显示文摘 | SECUNDINO I LOPEZ M C CERVANTES B L | 2006 | Immunology2006，117，1： | 1 |
| 7 | Presence of ehitinase and beta-N- acetylglucosaminidase in the A edes aegypti: A Achiti- nolytic system involving peritrophic matrix formation and degradation显示文摘 | Filho Benedito P D Lemos Francisco J A Secundino N6gila F C | 2002 | Insect Biochemistry and Molecular Biology2002，32，12： | 1 |
| 8 | In vivo ima- ging reveals an essential role for neutrophils in leishmani- asis transmitted by sand flies显示文摘 | Peters NC Egen JG Secundino N | 2008 | Science2008，，： | 1 |
| 9 | What is the optimal level of vitamin D in non-dialysis chronic kidney disease population?显示文摘AIM To evaluate thresholds for serum 25(OH)D concentrations in relation to death, kidney progression and hospitalization in non-dialysis chronic kidney disease(CKD) population.METHODS Four hundred and seventy non-dialysis 3-5 stage CKD patients participating in OSERCE-2 study, a prospective, multicenter, cohort study, were prospectively evaluated and categorized into 3 groups according to 25(OH)D levels at enrollment(less than 20 ng/mL, between 20 and 29 ng/mL, and at or above 30 ng/mL), considering 25(OH)D between 20 and 29 ng/mL as reference group. Association between 25(OH)D levels and death(primary outcome), and time to first hospitalization and renal progression(secondary outcomes) over a 3-year followup, were assessed by Kaplan-Meier survival curves and Cox-proportional hazard models. To identify 25(OH)D levels at highest risk for outcomes, receiver operating characteristic(ROC) curves were performed.RESULTS Over 29 ± 12 mo of follow-up, 46(10%) patients dead, 156(33%) showed kidney progression, and 126(27%) were hospitalized. After multivariate adjustment, 25(OH)D < 20 ng/mL was an independent predictor of all-cause mortality(HR = 2.33; 95%CI: 1.10-4.91; P = 0.027) and kidney progression(HR = 2.46; 95%CI: 1.63-3.71; P < 0.001), whereas the group with 25(OH)D at or above 30 ng/mL did not have a different hazard for outcomes from the reference group. Hospitalization outcomes were predicted by 25(OH) levels(HR = 0.98; 95%CI: 0.96-1.00; P = 0.027) in the unadjusted Cox proportional hazards model, but not after multivariate adjusting. ROC curves identified 25(OH)D levels at highest risk for death, kidney progression, and hospitalization, at 17.4 ng/mL [area under the curve(AUC) = 0.60; 95%CI: 0.685-0.69; P = 0.027], 18.6 ng/mL(AUC = 0.65; 95%CI: 0.60-0.71; P < 0.001), and 19.0 ng/m L(AUC = 0.56; 95%CI: 0.50-0.62; P = 0.048), respectively.CONCLUSION25(OH)D < 20 ng/mL was an independent predictor of death and progression in patients with stage 3-5 CKD, with no additional benefits when patients reached the levels at or above 30 ng/m L suggested as optimal by CKD guidelines. | Pablo Molina JoséL Górriz Mariola D Molina Sandra Beltrán Belén Vizcaíno Verónica Escudero Julia Kanter Ana Iávila Jordi Bover Elvira Fernández Javier Nieto Secundino Cigarrán Enrique Gruss Gema Fernández-Juárez Alberto Martínez-Castelao Juan F Navarro-González Ramón Romero Luis M Pallardó | 2016 | World Journal of Nephrology2016，5，5： | 1 |
| 10 | Dexamethasone down-regulates the inflammatory mediators but fails to reduce the tissue injury in the lung of acute pancreatitis rat models显示文摘 | Sara Yubero Manuel A. Manso Laura Ramudo Secundino Vicente Isabel De Dios | 2012 | Pulmonary Pharmacology & Therapeutics2012，，4： | 1 |
| 11 | Presence of chitinase and beta-N- acetylglucosaminidase in the Aedes aegypti A chitinolytic system involving peritrophic matrix formation and degradation显示文摘 | Filho B Lemos F Secundino N | 2002 | Insect Biochem Mol Biol2002，32，： | 1 |
| 12 | Salmonella porins induce a sustained, lifelong bactericidalanti-body memoru response 显示文摘 | Ismael Secundino Constantino Lopez-Macias Luisa Cervantes- Barragan | 2005 | Immunology2005，117，： | 1 |
| 13 | The N-2- phenylethyleinnamamide from Spilanthes ocymifolia 显示文摘 | Borges D Vazquez P Secundino M | 1984 | Phytoehemistry1984，23，11： | 1 |
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