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| 1 | Hydrogen cyanide production by soil bacteria: Biological control of pests and promotion of plant growth in sustainable agriculture显示文摘Currently, plant diseases and insect infestations are mainly controlled by the extraneous application of pesticides. Unfortunately, the indiscriminate use of such agrochemicals can cause ecological and environmental problems, as well as human health hazards. To obviate the potential pollution arising from the application of agrochemicals, biological control of soilborne pathogens or insect pests using antagonistic microorganisms may be employed. Certain soil bacteria, algae, fungi, plants and insects possess the unique ability to produce hydrogen cyanide(HCN), which plays an important role in the biotic interactions of those organisms. In particular, cyanogenic bacteria have been found to inhibit the growth of various pathogenic fungi, weeds, insects, termites and nematodes. Thus, the use of HCN-producing bacteria as biopesticides offers an ecofriendly approach for sustainable agriculture. The enzyme, HCN synthase,involved in the synthesis of HCN, is encoded by the hcnABC gene cluster. The biosynthetic regulation of HCN, antibiotics and fluorescent insecticidal toxins through the conserved global regulatory GacS/GacA system is elaborated in this review, including approaches that may optimize cyanogenesis for enhanced pest control. In addition, the effects of bacterially synthesized HCN on the production of indole acetic acid, antibiotics and fluorescent insecticidal toxins, 1-aminocyclopropane-1-carboxylate deaminase utilization and phosphate solubilization may result in the stimulation of plant growth. A more detailed understanding of HCN biosynthesis and regulation may help to elaborate the precise role of this compound in biotic interactions and sustainable agriculture. | Anju SEHRAWAT Satyavir S.SINDHU Bernard R.GLICK | 2022 | Pedosphere2022，32，1： | 4 |
| 2 | Hybridization between salt resistant and salt susceptible genotypes of mungbean(Vigna radiata L.Wilczek)and purity testing of the hybrids using SSRs markers显示文摘Six cultivated and two wild genotypes of mungbean(Vigna radiata L. Wilczek) possessing variation for phenotypic and genotypic response for salt tolerance were hybridized. Hybridization results showed successful pod set and significant variations in cross-compatibility of investigated genotypes. Genotypes PLM 380 and PLM 562 showed promising combining ability with all genotypes. Results revealed significant crossing compatibility between V. radiata and V. sublobata. The cross ability ranged from 1.99 to 5.12%(average 3.08%). Molecular analysis confirmed the hybrids purity. All F_1 seeds were bold, green/shiny green and germinated between 3 to 5 days. Hybrid plants were normal, fertile and healthier over their respective progenitors. Uniform flowering and maturity of the hybrids showed absence of any defect or alteration in plant habit and life cycle of the hybrids. The hybrid plants showed increase in yield characteristics as no. of pods, pod length, 100 seeds weight, and yield per plant. Number of pods containing F_2 seeds ranged from 5–8 per cluster. The F_2 seeds were collected and stored for further research. Present study suggests that salt resistant wild relatives or cultivars of mungbean can be explored by breeding as a source of useful traits/genes providing salt tolerance. This may help in development of best mungbean variety for saline prone areas. Micro-satellite markers linked to the trait/genes may assist breeding by early selection of the genotypes compared to the phenotypic screening. | Sehrawat Nirmala Yadav Mukesh Bhat Kangila Venkataraman Sairam Raj Kumar Jaiwal Pawan Kumar | 2016 | Journal of Integrative Agriculture2016，15，3： | 3 |
| 3 | Butein imparts free radical scavenging, anti-oxidative and proapoptotic properties in the flower extracts of Butea monosperma显示文摘The flower of Butea monosperma(Lam.)(Fabaceae)has been used in traditional Indian medicine in the treatment of many ailments including liver disorders.To understand the pharmacological basis of its beneficial effects,the extracts of dried flowers in water,methanol,butanol,ethyl acetate and acetone were evaluated for free radical scavenging and pro-apoptotic activities in cell cultures(human hepatoma Huh-7 cell line and immortalized AML-12 mouse hepatocytes).Butrin and butein-the active constituents of flower extracts-were used as reference molecules.The levels of cell injury markers like lactate dehydrogenase,glutathione and lipid peroxidation and primary antioxidant enzymes glutathione S-transferase and catalase were also measured.The aqueous and butanolic extracts exhibited better 2,2-diphenyl-1-picrylhydrazyl scavenging and cytotoxic activities in hepatoma cells than in immortalized hepatocytes.Interestingly,butein inhibited 2,2-diphenyl-1-picrylhydrazyl radical better than butrin.The aqueous and butanolic extracts were further investigated for hepatoprotection against carbon tertrachloride-induced biochemical changes and cell death.Both extracts,just as butrin and butein,significantly reversed the cellular glutathione levels and lipid peroxidation,and glutathione–S-transferase activity.Lactate dehydrogenase leakage and cell death were also prevented.However,only butein revived the catalase activity.Thus,the butein content of Butea monosperma flower extracts is important for free radical scavenging activity,apoptotic cell death and protection against oxidative injury in hepatic cells. | ANURADHA SEHRAWAT VIJAY KUMAR | 2012 | BIOCELL2012，36，2： | 2 |
| 4 | Role of IL-17 and Th17 cells in herpes simplex virus-induced corneal immunopathology显示文摘 | Suryawanshi A Veiga-Parga T Rajasagi NK Reddy PB Sehrawat S Sharma S Rouse BT | | 0，，04： | 1 |
| 5 | Evaluation of possiblemechanisms of protective role of Tamarix gallica againstDEN initiated and 2-AAF promoted hepatocarcinogenesisin male Wistar rats 显示文摘 | Sehrawat A Sultana S | 2006 | Life Sci2006，79，15： | 1 |
| 6 | Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators 显示文摘 | Sehrawat S Suryawanshi A Hirashima M | 2009 | J Immunol2009，182，5： | 1 |
| 7 | Role of SMC1 in Overcoming Drug Resistance in Triple Negative Breast Cancer 显示文摘 | Yadav S Sehrawat A Eroglu Z | 2013 | PLoS One2013，228，64： | 1 |
| 8 | Role of Tim-3/ galectin-9 inhibitory interaction in viral-induced immunopatholo- gy: shifting the balance toward regulators 显示文摘 | Sehrawat S Suryawanshi A Hirashima M | 2009 | J Immunol2009，182，5： | 1 |
| 9 | Genetic Polymorphism of Type 1 Intermediate Filament Wool Keratin Gene in Native Indian Sheep Breeds 显示文摘 | Arora R Bhatia S Sehrawat A | 2008 | Biochem Genet2008，46，： | 1 |
| 10 | Genetic Polymorphism of Type 1 Intermediate Filament Wool Keratin Gene in Native Indian Sheep Breeds显示文摘 | Arora R Bhatia S Sehrawat A | 2008 | Bioehem Genet2008，46，： | 1 |
| 11 | Tregs and infections: on the po- tential value of modifying their function显示文摘 | Sehrawat S Rouse BT | 2011 | J Leukoc Bi- ol2011，90，6： | 1 |
| 12 | Dietary chemopreven- tative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo 显示文摘 | Kim S H Sehrawat A Singh S V | 2013 | Cancer Prey Res ( Phila)2013，6，8： | 1 |
| 13 | Epitaxial growth of highly transparent and conducting Sc-doped ZnO films on c-plane sapphire by sol-gel process without buffer 显示文摘 | SHARMA R SEHRAWAT K MEHRA R M | 2010 | Current Appl Phys2010，10，： | 1 |
| 14 | Antioxidant activities and oxidative stress by products in human hypertension显示文摘 | Khullar M Relan V Sehrawat BS | 2004 | Hypertension2004，43，2： | 1 |
| 15 | Synergistic effect betweenapolipoprotein E and apolipoprotein Al gene polymorphisms in therisk for coronary artery disease 显示文摘 | Rai TS Khullar M Sehrawat BS | 2008 | Mol Cell Biochem2008，313，12： | 1 |
| 16 | Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer显示文摘 | Singhal SS Sehrawat A Sabu M | 2010 | Int J Cancer2010，126，： | 1 |
| 17 | Notch2 activation is protective against anticaneer effects of zerumbone in human breast cancer cells显示文摘 | Sehrawat A Sakao K Singh SV | 2014 | Breast Cancer Res Treat2014，146，3： | 1 |
| 18 | MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hyper- tension in Indians 显示文摘 | Markan S Sachdeva M Sehrawat BS | 2007 | Mol Cell Biochem2007，302，12： | 1 |
| 19 | Role of regulatory T cells during virus infection 显示文摘 | Veiga-Parga T Sehrawat S Rouse BT | 2013 | Immunol Rev2013，255，1： | 1 |
| 20 | Influence of galectin-9/ Tim-3 interaction on herpes simplex virus-1 latency 显示文摘 | Reddy PB Sehrawat S Suryawanshi A | 2011 | J Immunol2011，187，11： | 1 |
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