|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Index of a Projection 显示文摘 | Avron J Seiler R Simon B | 1994 | J Funct Anal1994,120,1: | 2 |
| 2 | Advances in cellulose ester performance and application显示文摘 | Kevin J Edgar Charles M Buchanan John S Debenham Paul A Rundquist Brian D Seiler Michael C Shelton Debra Tindall | 2001 | Progress in Polymer Science2001,,9: | 2 |
| 3 | Metabolite profile comparisons between ascending and descending colon tissue in healthy adults显示文摘BACKGROUND Obesity is a risk factor for colorectal cancer,yet metabolic distinctions between healthy right and left colon tissue,before cancer is diagnosed,remains largely unknown.This study compared right-ascending and left-descending colon tissue metabolomes to identify differences from the stool metabolome in normal weight,overweight,and obese adults.AIM To examine right and left colon tissue metabolites according to body mass index that may serve as mechanistic targets for interventions and biomarkers for colon cancer risk.METHODS Global,non-targeted metabolomics was applied to assess right-ascending and left-descending colon tissue collected from healthy adults undergoing screening colonoscopies to test the hypothesis that BMI differentially impacts colon tissue metabolite profiles.The colon tissue and stool metabolome of healthy adults(n=24)was analyzed for metabolite signatures and metabolic pathway networks implicated in progression of colorectal cancer.RESULTS Ascending and descending colon contained 504 host,food,and microbiotaderived metabolites from normal weight,overweight and obese adults grouped according to body mass index.Amino acids,lipids,and nucleotides were among the chemical types that further differentiated from the stool metabolite profiles.Normal weight adults had 46 significantly different metabolites between ascending and descending colon tissue locations,whereas there were 37 metabolite differences in overweight and 28 metabolite differences for obese adults(P<0.05).Obese adults had trimethylamine N-oxide,endocannabinoids and monoacylglycerols with different relative abundances identified between ascending and descending colon.Primary and secondary bile acids,vitamins,and fatty acids also showed marked relative abundance differences in colon tissue from overweight/obese adults.CONCLUSION There were metabolite profile differences between right-ascending and leftdescending colon tissue in healthy adults.Colon lipids and other metabolites in obese and overweight adults were distinguished from normal weight participants and associated with gut inflammation,nutrient absorption,and products of microbiota metabolism. | Bridget A Baxter Kristopher D Parker Michael J Nosler Sangeeta Rao Rebecca Craig Catherine Seiler Elizabeth P Ryan | 2020 | World Journal of Gastroenterology2020,26,3: | 2 |
| 4 | Determination of the compartment pressure threshold of muscle ischemia in a canine model显示文摘 | Matava M J Whitesides T E Jr Seiler J G 3rd | 1994 | J Trauma1994,37,: | 1 |
| 5 | Bid - mediated mito- chondrial damage is a key mechanism in glutamate - induced oxidative stress and AIF -dependent cell death in immortalized HT- 22 hippocampal neurons 显示文摘 | Tobaben S Grohm J Seiler A | 2011 | Cell Death & Differentia- tion2011,18,2: | 1 |
| 6 | Autogenous flexor tendon graft: a biomechanical and morphological study in dogs显示文摘 | Gelberman R H Williams C S | 1993 | J Bone Joint Surg1993,75,7: | 1 |
| 7 | Transplantation of embryonic retina to adult retina in rabbits显示文摘 | Seiler M J Aramant RB Ehinger B | 1991 | Exp Eye Res1991,51,: | 1 |
| 8 | Micromachining a miniaturized capillary electrophoresis-based chemical analysis system on a chip显示文摘 | Harrison D J Fluri K Seiler K | 1993 | Science1993,261,5123: | 1 |
| 9 | Activation of STATS during EPO - directed suppression of apoptosis显示文摘 | Bittorf T Seiler J Ludtke B | 2000 | Cell Signal2000,12,1: | 1 |
| 10 | Mesh stability of look-ahead inter connected systems显示文摘 | Pant A Seiler P Hedrick J K | | 0,,0018: | 1 |
| 11 | Development of a Colli- sion Avoidance System显示文摘 | SEILER P SONG B HEDRICK J | 1998 | SAE1998,,98: | 1 |
| 12 | Seed maturity, storage time and temperature, and media treatment effect on germination of two wild sunflowers显示文摘 | Seiler G J | 1998 | Agronomy Journal1998,90,: | 1 |
| 13 | Clinical use of cooled radiofrequency ablation显示文摘 | Vest J A Seiler J Stevenson W G | | 0,,07: | 1 |
| 14 | Gas exchange and canopy structure of 9-year-old loblolly pine,pitch pine and pitch × loblolly hybrids 显示文摘 | Samuelson L J Seiler J R Feret P P | 1992 | Trees1992,6,: | 1 |
| 15 | Transplantation of neuroblastic progenitor cells as a sheet preserves and restoresrctinal function显示文摘 | Seiler M J Aramant RB | | 0,,01: | 1 |
| 16 | Seed maturity, storage time and temperature, and media treatment effect on germination of two wild sunflowers 显示文摘 | Seiler G J | 1998 | Agronomy Journal1998,90,: | 1 |
| 17 | Polyamine transport in mammalian cells显示文摘 | Seiler N Delcros J Moulinoux J | 1996 | An update Int J Biochem Cell Biol1996,28,: | 1 |
| 18 | Evaluation and bioinduction of energy components of Jatropha curcas显示文摘 | AUGUSTUS G D P S JAYABALAN M SEILER G J | 2002 | Biomass and Bioenergy2002,23,: | 1 |
| 19 | Retinal transplantationinduced recovery of retinotectal visual function in a rodent model of retinitis pigmentosa显示文摘 | Sagdullaev B T Aramant R B Seiler M J | 2003 | Invest Ophthalmol Vis Sci2003,44,4: | 1 |
| 20 | A new approach to crystal- lographic orientation measurement for apatite fission track analysis, Effects of crystal morphology and implications for automation显示文摘 | Peternell M Kotdmann Fabian Wilson C J L Seiler Christian Gleadow A J W | 2009 | Chemical Geology2009,265,: | 1 |