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15篇 您的检索式:作者名="Senawong"
    题名 作者 年代 出处 被引量
1Hepatitis-B and hepatitis-C associated hepatocellular carcinoma: Evaluation of alpha-fetoprotein as a diagnostic marker显示文摘Songsivilai S Dharakul T Senawong S 1995Asian Pae J Allergy Immunol1995,13,2:1
2BCL1 1 A-dependent recruitment of S1RT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression显示文摘Senawong T Peterson VJ Leid M 0,,:1
3The correlation of beta subunit human chorionic gonadotropin level in the serum and first morning urine of patients with gestational trophoblastic disease显示文摘Benjapibal M Wataganara T Senawong S 2001J Med Assoc Th i2001,84,7:1
4BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression显示文摘Senawong T Peterson VJ Leid M 2005Arch Biochem Biophys2005,434,2:1
5COUP-TF (chicken oval- bumin upstream promoter transcription factor)- interacting pro- teinl (CTIP1)is a sequence- specific DNA binding protein 显示文摘Avram D Fields A Senawong T 2002Biochem J2002,368,2:1
6Germline mutations of MEK in cardio-facio-cutaneous syndrome are sensitive to MEK and RAF inhibition: implications for therapeutic options显示文摘Senawong T Phuchareon J Ohara O McCormick F Rauen KA Tetsu O 2008Hum Mol Genet2008,17,3:1
7Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter tran- scription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression显示文摘Senawong T Peterson V J Avram D 2003J Biol Chem2003,278,43:1
8Sirtl promotes fat mobilization in white adipocytes by repressing PPAR-gamma显示文摘Picard F Kurtev M Chung N Topark- Ngarm A Senawong T Machado De Oliveira 2004Nature2004,429,6993:1
9Diagnostic utility ofCYFRA 21 - 1 in malignant pleural effusion 显示文摘Dejsomritrutai W Senawong StPromkiamon B 2001Respirology y2001,6,3:1
10The correlation of beta-subunit human chorionic gonadotropin level in the serum and first morning urine of patients with gestational trophoblastic disease显示文摘Benjapibal M Wataganara T Senawong S 2001J Med Assoc Thai2001,84,7:1
11Hepatitis B and hepatitis C asso2ciated hepatocellular carcinoma : evaluation of alpha - fetop rotein as a di - agnostic marker 显示文摘Songsivilai S Dharakul T Senawong S 2005Asian Pac J Allergy Immunol2005,13,2:1
12The correlation of beta subunit human chorionic gonadotropin level in the serum and first morning urine of patients w th gestational trophoblastic disease显示文摘Benjapibal M Wataganara T Senawong S 2001J Med Assoc That2001,84,7:1
13Hepatitis B and hepatitis Cassociated hepatocellular carcinoma:evaluation of alpha-fetoprotein as a diagnostic marker显示文摘Songsivilai S Dharakul T Senawong S 1995Asian Pac J Allergy Immunol1995,13,:1
14The correlation of beta-subunit human chorionic gonadotropin level in the serum and first morning urine of patients with gestational trophoblastic disease显示文摘Benjapibal M Wataganara T Senawong S 2001Med Assoc Thai2001,84,7:1
15Cytotoxic effects of Thai noni juice product ethanolic extracts against cholangiocarcinoma cell lines显示文摘Objective:To investigate the cytotoxic activity and molecular mechanism(s)of two Thai noni juice(TNJ)products ethanolic extracts against cholangiocarcinoma(CCA)cell lines and non-cancerous cells,and to explore phenolic acid compositions of TNJ products.Methods:Phenolic acid profiles of TNJ Chiangrai(TNJ-Cr)and TNJ Buasri(TNJ-Bs)ethanolic extracts were determined by HPLC.The cytotoxicity of TNJ ethanolic extracts on cancer and non-cancerous cells was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and trypan blue assays.Mechanism(s)underlying the anti-CCA activity of TNJ ethanolic extracts were determined by cell cycle,apoptosis,and reactive oxygen species(ROS)generation assays.The expression levels of proteins involved in apoptosis and ERK signaling were evaluated by Western blot analysis.Results:Phenolic acid profiles of both TNJ ethanolic extracts showed that the p-hydroxybenzoic,vanillic,and protocatechuic acids were the major phenolic acids in TNJ products.Cytotoxicity assays revealed that the TNJ-Cr and TNJ-Bs ethanolic extracts reduced viability of CCA cell lines through induction of apoptosis by up-regulation of p53 and Bax proapoptotic proteins.Both TNJ ethanolic extracts promoted ROS generation by activating the ERK1/2 signaling in well-differentiated CCA cells KKU-213B.Meanwhile,TNJ ethanolic extracts did not induce ROS production in poorly differentiated CCA cells KKU-100.Both TNJ ethanolic extracts showed no toxicity to human peripheral blood mononuclear cells.Conclusions:TNJ ethanolic extracts could inhibit CCA cell proliferation by inducing ROS generation and apoptosis and may be applicable for combination therapies in CCA treatment.Jeerati Prompipak Thanaset Senawong Banchob Sripa Prasan Swatsitang Paweena Wongphakham Gulsiri Senawong 2021Asian Pacific Journal of Tropical Biomedicine2021,11,8:0
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