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2篇 您的检索式:作者名="Senthilkumar Damodaran"
    题名 作者 年代 出处 被引量
1Acute Myeloid Leukemia Secondary to Oxaliplatin Treatment for Esophageal Cancer显示文摘Senthilkumar Damodaran Tanya Bellavia Sheila N.J. Sait Eunice S. Wang Meir Wetzler Nikhil I. Khushalani 2012Clinical Colorectal Cancer2012,,2:1
2Evaluating Peptide Mass Fingerprinting-based Protein Identification显示文摘Identification of proteins by mass spectrometry (MS) is an essential step in pro-teomic studies and is typically accomplished by either peptide mass fingerprinting (PMF) or amino acid sequencing of the peptide. Although sequence information from MS/MS analysis can be used to validate PMF-based protein identification,it may not be practical when analyzing a large number of proteins and when high-throughput MS/MS instrumentation is not readily available. At present,a vast majority of proteomic studies employ PMF. However,there are huge disparities in criteria used to identify proteins using PMF. Therefore,to reduce incorrect protein identification using PMF,and also to increase confidence in PMF-based protein identification without accompanying MS/MS analysis,definitive guiding principles are essential. To this end,we propose a value-based scoring system that provides guidance on evaluating when PMF-based protein identification can be deemed sufficient without accompanying amino acid sequence data from MS/MS analysis.Senthilkumar Damodaran Troy D.Wood Priyadharsini Nagarajan Richard A.Rabin 2007Genomics, Proteomics & Bioinformatics2007,5,3:0
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