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70篇 您的检索式:作者名="Sercarz"
    题名 作者 年代 出处 被引量
1Antigen Processing by Autoreactive B Cells Promotes Determinant Spreading显示文摘Acute primary immune responses tend to focus on few immunodominant determinants using a very limited number of T cell clones for expansion, whereas chronic inflammatory responses generally recruit a large number of different T cell clones to attack a broader range of determinants of the invading pathogens or the inflamed tissues.In T cell-mediated organ-specific autoimmune disease, a transition from the acute to the chronic phase contributes to pathogenesis, and the broadening process is called determinant spreading. The cellular components catalyzing the spreading reaction are not identified. It has been suggested that autoreactive B cells may play a central role in diversifying autoreactive T cell responses, possibly through affecting antigen processing and presentation. The clonal identity and diversity of the B cells and antibodies seem critical in regulating T cell activity and subsequent tissue damage or repair. Here, we use two autoimmune animal models, experimental autoimmune thyroiditis (EAT)and type 1 diabetes (T1D), to discuss how autoreactive B cells or antibodies alter the processing and presentation of autoantigens to regulate specific T cell response.Yang D. Dai George Carayanniotis Eli Sercarz 2005Cellular & Molecular Immunology2005,2,3:4
2Induction of anti-seif-immunity to cure显示文摘Nanda NK Sercarz EE 1995Cancer Cell1995,82,:1
3Mechanisms of T and B cell collaboration to the in vitro preduction of anti-DNA antibodies in the NZB/NZW F1 murine SLE model 显示文摘 Sercarz E E Hahn B H 1987J Immunol1987,138,:1
4Noninvasive measurement of traveling wave velocity in canine larynx 显示文摘Nasri S Sercarz JA Berke GS 1994Ann Oral Rhinol Laryngol1994,103,10:1
5Analysis of outcome and complications in 400 cases of microvascular head and neck reconstruction显示文摘Suh JD Sercarz JA Abemayor E 2004Arch Otolaryngol Head Neck Surg2004,130,8:1
6Clinicalandpathologic distinction between pramary and metastatic mucasal melanoma of the head and neck显示文摘Billings KR Wang MB Sercarz JA 0,,06:1
7Immunodominance in the TCR repertoire of {alpha} TCR peptide-specific CD4+ Treg population that controls experimental autoimmune encephalomyelitis 显示文摘MADAKAMUTIL L T MARICIC I SERCARZ E E 2008J Immunol2008,180,7:1
8Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65显示文摘Moudgil KD Kim E Yun OJ Chi HH Brahn E Sercarz EE 2001J Immunol2001,166,:1
9Processing creates the self显示文摘Sercarz ee 2002Nat lmmunol2002,3,2:1
10Specificity and interactions of CD8^+ T suppressor cells显示文摘Krzych U Nanda N Sercarz E 1989Res Immunol1989,140,3:1
11Clinical and pathologic distinction between primary and metastatic mucosal melanoma of the head and neck显示文摘Billings KR Wang MB Sercarz JA 1995Otolaryngol Head Neck Surg1995,112,6:1
12Clinical and pathologic distinction between primary and metastatic mucosal melanoma of the head and neck显示文摘Billings KR Wang MB Sercarz JA 1995Otolaryngol Head Neck Surg1995,112,6:1
13Analysis of outcome and complications in 400 cases of microvascular head and neck reconstruction 显示文摘Suh JD Sercarz JA Abemayor E 2004Arch Otolaryngol Head Neck Snrg2004,130,8:1
14A new technique for quantitative measurement of larygeal videostroboscopic images 显示文摘Sercarz JA Berke GS Amstein D 1991Arch Otolaryngol Head Neck Surg1991,,:1
15T cell vaccination in experimental autoimmune encephalomyelitis: a mathematical model 显示文摘BORQHANS JA DE BOER RJ SERCARZ E 1998J Immunol1998,161,3:1
16Harnessing self-reactivity in cancer immunotherapy显示文摘Schoenberger SP Sercarz EE 1996Semin Immunol1996,8,5:1
17Fixation of mandibular osteotomies:comparison of locking and nonlocking hardware 显示文摘Kim Y Smith J Sercarz JA 2007Head Neck2007,29,5:1
18Mucosa-associated lymph-joid tissue lymphoma of the lingual tonsil显示文摘Lee JT Paquette R Sercarz JA 2002Am J Otolaryngol2002,21,4:1
19Radiographic assessment of inverted papilloma显示文摘Head C S Sercarz J A Luu Q Collins J 2007Acta Otolaryngol2007,127,5:1
20Mucosa - associated lymphoid tissue lymphoma of the lingual tonsil 显示文摘LEE JT PAYUE3'TE R SERCARZ JA 2010Am J Otolaryngo 12010,21,4:1
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