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241篇 您的检索式:作者名="Serfaty"
    题名 作者 年代 出处 被引量
1原发性胆汁性肝硬化:自身免疫性肝炎重叠综合征的长期预后和疗效显示文摘Background/Aims: Whether primary biliary cirrhosis (PBC) autoimmune hepatitis (AIH) overlap syndrome requires immunosuppressive therapy in addition to ursodeoxycholic acid (UDCA) is a controversial issue. Methods: Seventeen patients with simultaneous form of strictly defined overlap were followed for 7.5 years. First-line treatment was UDCA alone (UDCA) in 11 and combination of immunosuppressors and UDCA (UDCA+ IS) in 6. Results: Characteristics at presentation were not significantly different between the 2 groups. In the UDCA+ IS group (f-up 7.3 years), biochemical response in terms of AIH features (ALT< 2ULN and IgG< 16 g/L) was achieved in 4/6 and fibrosis did not progress. In the UDCA group, biochemical response was observed in three patients together with stable or decreased fibrosis (f-up 4.5 years) whereas the eight others were non-responders with increased fibrosis in four (f-up 1.6 years). Seven of these eight patients subsequently received combined therapy for 3 years. Biochemical response was obtained in 6/7 and no further increase of fibrosis was demonstrated. Overall, fibrosis progression in non-cirrhotic patients occurred more frequently under UDCA monotherapy (4/8) than under combined therapy (0/6) (P=0.04). Conclusions: Combination of UDCA and immunosuppressors appears to be the best therapeutic option for strictly defined PBC-AIH overlap syndrome.Chazouillères O. Wendum D. Serfaty L. 赵菊辉(译) 尹勇(校) 2006世界核心医学期刊文摘(胃肠病学分册)2006,2,5:3
2Chronic Hepatitis B Virus Carriers in the Immunotolerant Phase of Infection: Histologic Findings and Outcome显示文摘Tony Andreani Lawrence Serfaty Djamila Mohand Salem Dernaika Dominique Wendum Olivier Chazouillères Raoul Poupon 2007Clinical Gastroenterology and Hepatology2007,,5:2
3Improved survival after variceal bleeding in patients with cirrhosis over the past two decades显示文摘CARBONELL N PAUWELS A SERFATY L 2004Hepatology2004,40,3:1
4Overestimation of moderate carotid stenosis assessed by both Doppler US and contrast enhanced 3D-MR angiography in the CARMEDAS study显示文摘Nonent M Ben Salem D Serfaty JM 0,,03:1
5Atherosclerotic plaques:classification and characterization with T2-weighted high-spatial resolution MR imaging-An invitro study显示文摘Serfaty JM Chaabane L Tabib A 0,,05:1
6Stigma: the feelings and experiences of 46 people with mental illness 显示文摘Dinos S Stevens S Serfaty M 2004British Journal of Psychiatry2004,184,6:1
7Dynamic and cyclic fatigue of enginedriven rotary nickel-titanium endodontic instruments显示文摘Haikel Y Serfaty R Bateman G 1999J Endod1999,25,6:1
8Dynamic and cyclic fatigue of engine-driven rotary nickel -titanium endodontic instruments显示文摘Haikel Y Serfaty R Bateman G 1999J Endod1999,25,6:1
9Hepatitis C virus induced hypohetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C显示文摘Serfaty L Andreani T Giral P 2001J Hepatol2001,,34:1
10RU486:current and potential inclications, greatexpectations and strong resistance显示文摘Serfaty D 1995Presse Med1995,24,16:1
11Dynamic and cyclic fatigue of engine-driven rotary nickel-titanium endodontic instruments显示文摘Haikel Y Serfaty R Bateman G 1999J Endod1999,25,6:1
12Long tern outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome显示文摘Chazouilleres O Wendum D Serfaty L 2006J Heparol2006,44,2:1
13A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment显示文摘Eric Lawitz Maribel Rodriguez-Torres Albrecht Stoehr Edward J. Gane Lawrence Serfaty Sanhita Bhanja Richard J. Barnard Di An Jacqueline Gress Peggy Hwang Niloufar Mobashery 2013Journal of Hepatology2013,,1:1
14Plaque density on CT,a potential marker of ischemic stroke显示文摘 Nonent M Nighoghossian N 2006Neurology2006,66,:1
15Overestimation of moderate carotid stenosis assessed by both Doppler US and contrast enhanced 3D-MR angiography in the CARMEDAS study显示文摘Nonent M Ben Salem D Serfaty JM 2010J Neuroradiol2010,5,2:1
16Prognostic value of serum hyaluronan in patients with compensated HCV cirrhosis显示文摘Guechot J Serfaty L Bonnand AM 2000J Hepatol2000,32,3:1
17Accuracy of three-dimen- sional gadolinium-enhanced MR angiography in the assessment of ex- tracranial carotid artery disease 显示文摘Serfaty JM Chirossel P Chevallier JM 2000AJR Am J Roentgenol2000,175,2:1
18Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial显示文摘Vlad Ratziu Philippe Giral Sophie Jacqueminet Fréderic Charlotte Agnès Hartemann–Heurtier Lawrence Serfaty Philippe Podevin Jean–Marc Lacorte Carole Bernhardt Eric Bruckert André Grimaldi Thierry Poynard 2008Gastroenterology2008,,1:1
19Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome:clinical features and response to therapy显示文摘 Wendum D Serfaty L 1998Hepatology1998,28,2:1
20Ursodeoxycholic acid and chemoprevention of colorectal cancer显示文摘Serfaty L Bissonnette M Poupon R 2010Gastroentérol Clin Biol2010,34,10:1
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