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| 1 | A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value显示文摘 | Changsong Zou Aojun Chen Lihong Xiao Heike M Muller Peter Ache Georg Haberer Meiling Zhang Wei Jia Ping Deng Ru Huang Daniel Lang Feng Li Dongliang Zhan Xiangyun Wu Hui Zhang Jennifer Bohm Renyi Liu Sergey Shabala Rainer Hedrich Jian-Kang Zhu Heng Zhang | 2017 | Cell Research2017，27，11： | 22 |
| 2 | High-fidelity multimode fibre-based endoscopy for deep brain in vivo imaging显示文摘Progress in neuroscience relies on new techniques for investigating the complex dynamics of neuronal networks.An ongoing challenge is to achieve minimally invasive and high-resolution observations of neuronal activity in vivo inside deep brain areas.Recently introduced methods for holographic control of light propagation in complex media enable the use of a hair-thin multimode optical fibre as an ultranarrow imaging tool.Compared to endoscopes based on graded-index lenses or fibre bundles,this new approach offers a footprint reduction exceeding an order of magnitude,combined with a significant enhancement in resolution.We designed a compact and high-speed system for fluorescent imaging at the tip of a fibre,achieving a resolution of 1.18±0.04μm across a 50-μm field of view,yielding 7-kilopixel images at a rate of 3.5 frames/s.Furthermore,we demonstrate in vivo observations of cell bodies and processes of inhibitory neurons within deep layers of the visual cortex and hippocampus of anaesthetised mice.This study paves the way for modern microscopy to be applied deep inside tissues of living animal models while exerting a minimal impact on their structural and functional properties. | Sergey Turtaev Ivo T.Leite Tristan Altwegg-Boussac Janelle M.P.Pakan Nathalie L.Rochefort Tomáš Čižmár | 2018 | Light(Science & Applications)2018，7，1： | 8 |
| 3 | Updated Kimura-Takemoto classification of atrophic gastritis显示文摘BACKGROUND The Updated Sydney system for visual evaluation of gastric mucosal atrophy viaendoscopic observation is subject to sampling error and interobserver variability.The Kimura-Takemoto classification system was developed to overcome theselimitations.AIMTo compare the morphological classification of atrophic gastritis between theKimura-Takemoto system and the Updated Sydney system.METHODSA total of 169 patients with atrophic gastritis were selected according to diagnosisby the visual endoscopic Kimura-Takemoto method. Following the UpdatedKimura-Takemoto classification system, one antrum biopsy and five gastriccorpus biopsies were taken according to the visual stages of the Kimura-Takemoto system. The Updated Kimura-Takemoto classification system was thenapplied to each and showed 165 to have histological mucosal atrophy;theremaining 4 patients had no histological evidence of atrophy in any biopsy. The Updated Kimura-Takemoto classification was verified as a referencemorphological method and applied for the diagnosis of atrophic gastritis. Addingone more biopsy from the antrum to the six biopsies according to the Updated Kimura-Takemoto classification, constitutes the updated combined Kimura-Takemoto classification and Sydney system.RESULTSThe sensitivity for degree of mucosal atrophy assessed by the Updated Sydneysystem was 25% for mild, 36% for moderate, and 42% for severe, when comparedwith the Updated Kimura-Takemoto classification of atrophic gastritis formorphological diagnosis. Four types of multifocal atrophic gastritis wereidentified: sequential uniform (type 1;in 28%), sequential non-uniform (type 2;in7%), diffuse uniform (type 3;in 23%), diffuse non-uniform (type 4;in 24%), and'alternating atrophic – non-atrophic' (type 5;in 18%). The pattern of the spread ofatrophy, sequentially from the antrum to the cardiac segment of the stomach,which was described by the Updated Kimura-Takemoto system, washistologically confirmed in 82% of cases evaluated.CONCLUSIONThe Updated Sydney system is significantly inferior to the Updated Kimura-Takemoto classification for morphological verification of atrophic gastritis. | Sergey M Kotelevets Sergey A Chekh Sergey Z Chukov | 2021 | World Journal of Clinical Cases2021，9，13： | 8 |
| 4 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 5 | CD133 expression is not restricted to stem cells, and both CD133^sup +^ and CD133^sup -^ metastatic colon cancer cells initiate tumors显示文摘 | Shmelkov Sergey V Butler Jason M Hooper Andrea T Hormigo Adilia Kushner Jared Milde Till Clair Ryan St Baljevic Muhamed White Ian Jin David K Chadburn Amy Murphy Andrew J Valenzuela David M Gale Nicholas W Thurston Gavin Yancopoulos George | 2008 | Journal of Clinical Investigation2008，，： | 2 |
| 6 | Effect of fluence and ambient environment on the surface and structural modification of femtosecond laser irradiated Ti显示文摘Under certain conditions, ultrafast pulsed laser interaction with matter leads to the formation of self-organized conical as well as periodic surface structures(commonly reffered to as, laser induced periodic surface structures, LIPSS). The purpose of the present investigations is to explore the effect of fsec laser fluence and ambient environments(Vacuum &O_2) on the formation of LIPSS and conical structures on the Ti surface. The surface morphology was investigated by scanning electron microscope(SEM). The ablation threshold with single and multiple(N = 100) shots and the existence of an incubation effect was demonstrated by SEM investigations for both the vacuum and the O_2 environment. The phase analysis and chemical composition of the exposed targets were performed by x-ray diffraction(XRD) and energy dispersive x-ray spectroscopy(EDS), respectively. SEM investigations reveal the formation of LIPSS(nano & micro). FFT d-spacing calculations illustrate the dependence of periodicity on the fluence and ambient environment. The periodicity of nano-scale LIPSS is higher in the case of irradiation under vacuum conditions as compared to O_2. Furthermore, the O2 environment reduces the ablation threshold. XRD data reveal that for the O_2 environment, new phases(oxides of Ti) are formed. EDS analysis exhibits that after irradiation under vacuum conditions, the percentage of impurity element(Al) is reduced. The irradiation in the O_2 environment results in 15% atomic diffusion of oxygen. | Umm-i-Kalsoom Shazia Bashir Nisar Ali M Shahid Rafique Wolfgang Husinsky Chandra S R Nathala Sergey V Makarov Narjis Begum | 2016 | Chinese Physics B2016，25，1： | 2 |
| 7 | On-target temporal characterization of optical pulses at relativistic intensity显示文摘High-field experiments are very sensitive to the exact value of the peak intensity of an optical pulse due to the nonlinearity of the underlying processes.Therefore,precise knowledge of the pulse intensity,which is mainly limited by the accuracy of the temporal characterization,is a key prerequisite for the correct interpretation of experimental data.While the detection of energy and spatial profile is well established,the unambiguous temporal characterization of intense optical pulses,another important parameter required for intensity evaluation,remains a challenge,especially at relativistic intensities and a few-cycle pulse duration.Here,we report on the progress in the temporal characterization of intense laser pulses and present the relativistic surface second harmonic generation dispersion scan(RSSHG-D-scan)—a new approach allowing direct on-target temporal characterization of high-energy,few-cycle optical pulses at relativistic intensity. | Vyacheslav E.Leshchenko Alexander Kessel Olga Jahn Mathias Kruger Andreas Münzer Sergei ATrushin Laszlo Veisz Zsuzsanna Major Stefan Karsch | 2019 | Light(Science & Applications)2019，8，1： | 2 |
| 8 | Influence of impurities of the properties of rare-earth-doped barium-titanate ceramice显示文摘 | Maya D Glinchuk Lgor P Bykov Sergei M Kornie-nko | 2000 | J Mater Chem2000，10，： | 2 |
| 9 | The effect of self-focusing on laser space-debris cleaning显示文摘A ground-based laser system for space-debris cleaning will use powerful laser pulses that can self-focus while propagating through the atmosphere.We demonstrate that for the relevant laser parameters,this self-focusing can noticeably decrease the laser intensity on the target.We show that the detrimental effect can be,to a great extent,compensated for by applying the optimal initial beam defocusing.The effect of laser elevation on the system performance is discussed. | Alexander M Rubenchik Michail P Fedoruk Sergei K Turitsyn | 2014 | Light(Science & Applications)2014，3，1： | 2 |
| 10 | Computer simulations of electrokinetic injection techniques in microfluidic devices 显示文摘 | Sergey V E Stephen C J Ramsey J M | 2000 | Anal Chem2000，72，15： | 1 |
| 11 | Depoly merization of Lignin in Wood withMolecular Hydrogen Iodid 显示文摘 | Sergey M Shevchenko | 2000 | Croatica Chemica Acta2000，73，3： | 1 |
| 12 | Management of displaced intraarticu lar calcaneal fractures by using external ring fixation,minimally invasive open reduction,and early weight bearing显示文摘 | George R Sergei Y | 2004 | J Foot Ankle Surg2004，43，1： | 1 |
| 13 | A piezoactuated droplet-dispensing microfluidic chip显示文摘 | MOHAMMED J A SERGEY I G RIDHA B M | 2010 | Journal of Microelectromchannical Systems2010，19，1： | 1 |
| 14 | Variable selection in near-infrared spectroscopy:Benchmarking of feature selection methods on biodiesel data显示文摘 | Roman M Balabin Sergey V Smirnov | 2011 | Analytica Chimica Acta2011，692，： | 1 |
| 15 | Synthesis of protective Mo-Si-B coatings in molten salts and their oxidation behavior in an air-water mixture 显示文摘 | Sergey A Kuznetsov Evgeny V Rebov Martijn J M M | 2006 | Surface and Coatings Technology2006，201，34： | 1 |
| 16 | JPhys Chem B 显示文摘 | Chert J Apparao M R Sergei Lyuksyutov | 2001 | 105(13): 25252001，105，13： | 1 |
| 17 | 显示文摘 | Sergei I N Yuri K Yitzhak M | 2002 | The European Journal o5 Neuroscience2002，12，： | 1 |
| 18 | Infrared luminescence of ytterbium ion in complexes with calixresorcinarenes显示文摘 | Sergey V S Natalia V R Anna M T | 1998 | Journal of Fluorescence1998，8，3： | 1 |
| 19 | Sonochemi-cal approach to the synthesis of Fe3 04 @ Si02 core-shell nanoparticles with tunable properties 显示文摘 | Anne L M Sergei I N Karine G | 2008 | ACSnano2008，2，5： | 1 |
| 20 | Adaptive input-output linearing control of induction motors显示文摘 | RICCARDO M SERGEI P PAOLO V | 1993 | IEEE Trans on Automat Contr1993，38，2： | 1 |
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