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	题名	作者	年代	出处	被引量
1	Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages.	Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta	2017	Asian Pacific Journal of Tropical Biomedicine2017，7，3：	3
2	Effects of continuous versus bolus infusion of enteral nutrition in critical patients显示文摘	Serpa LF Kimura M Faintuch J	2003	Rev Hosp Clin Fac Med Sao Paulo2003，58，1：	1
3	Bisphosphonate therapy in patients under androgen deprivation therapy for prostate cancer: a systematic review and meta- analysis 显示文摘	Serpa Neto A Tobias-Machado M Esteves MA	2012	Prostate Cancer Prostatic Dis2012，15，1：	1
4	Performance assessment of solution methods for load distribution problem of gear teeth 显示文摘	Wink C H Serpa A L	2008	Mech Mach Theory2008，43，1：	1
5	Gaining control of corporate culture显示文摘	Kilman R Saxton M Serpa R	1985	San Francisco:Jossey Bass1985，，：	1
6	Vasopressinand terlipressin in adult vasodilatory shock:a systematicreview and meta-analysis of nine randomized controlledtrials显示文摘	Serpa Neto A Nassar AP Cardoso SO	2012	Crit Care2012，16，4：	1
7	Effects of contin- uous versus bolus infusion of enteral nutrition in critical pa- tients 显示文摘	Serpa L F Kimura M Faintuch J	2003	Rev Hosp Clin Fac Med Sao Paulo2003，58，1：	1
8	Late Cenozoic sedimentation and volcanism during transtensional deformation in Wingate Wash and the Owlshead Mountains,Death Valley显示文摘	Luckow H G Pavlis T L Serpa L F	2005	Earth-Science Reviews2005，73，：	1
9	Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome:a meta-analysis显示文摘	Serpa Neto A Cardoso SO Manetta JA		0，，：	1
10	Performance assessment of solution methods for load distribution problem of gear teeth 显示文摘	Carlos Henrique Wink Alberto Luiz Serpa	2008	Mechanism and Machine theory2008，，43：	1
11	Vasopressin and terlipressin in adult vasodilatory shock:a systematic review and meta-analysis of nine randomized controlled trials显示文摘	Serpa Neto A Nassar AP J ú nior Cardoso SO		0，，04：	1
12	A modified direct power control strategy allowing the connection of three-phase inverters to the grid through LCL filters显示文摘	Augusto Serpa L Ponnaluri S Mantovanelli Barbosa P	2007	IEEE Transactions on Industrial Applications2007，43，5：	1
13	A modified direct power control strategy allowing the connection of three-phase inverter to the grid through LCL filters显示文摘	Serpa L A Kolar J W Ponnaluri S	2005	IEEE Industry Applications Society2005，1，：	1
14	A modified direct power control strategy allowing the connection of three-phase inverters to the grid through LCL filters显示文摘	Serpa L A Ponnaluri S Barbosa P M	2007	IEEE Transactions on Industry Applications2007，43，5：	1
15	Relation of uric acid with components of metabolic syndrome before and after Roux-en-Y gastric bypass in morbidly obese subjects显示文摘	SERPA NETO A ROSSI FM VALLE LG	2011	Arq Bras Endocrinol Metabol2011，55，1：	1
16	Contemporary neurosurgical approaches to neurocysticercosis显示文摘	Rangel-Castilla L Serpa JA Gopinath SP	2009	Am J Trop Med Hyg2009，80，3：	1
17	A modified direct powercontrol strategy allowing the connection of three-phase inverter to thegrid through LCL filters显示文摘	Serpa L A Kolar J W Ponnaluri S	2005	IEEE Industry Applications Society(S0197-2618)2005，1，8：	1
18	Apieotomy as treatment for failure of ortho- dontic traction 显示文摘	Os6rio Leandro Berni Ferrazzo Vilmar Antonio Serpa Geraldo Fer- razzo Kfvia Linhares	2014	Case reports in dentistry2014，，：	1
19	Contemporary neu rosurgical approaches to neurocysticercosis 显示文摘	Rangel-Castilla L Serpa JA Gopinath SP	2009	Am J Trop Med Hyg2009，80，3：	1
20	Intraopera- tive ventilation strategies to prevent postoperative pulmonary complications : Systematic review, meta - analysis, and tri- al sequential analysis 显示文摘	Serpa Neto A Schuhz MJ Gama de Abreu M	2015	Best Pract Res Clin Anaesthesi- ol2015，29，3：	1

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