|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cirrhotic cardiomyopathy显示文摘During the course of cirrhosis, there is a progressive deterioration of cardiac function manifested by the disappearance of the hyperdynamic circulation due to afailure in heart function with decreased cardiac output. This is due to a deterioration in inotropic and chronotropic function which takes place in parallel with a diastolic dysfunction and cardiac hypertrophy in the absence of other known cardiac disease. Other findings of this specific cardiomyopathy include impaired contractile responsiveness to stress stimuli and electrophysiological abnormalities with prolonged QT interval. The pathogenic mechanisms of cirrhotic cardiomyopathy include impairment of the b-adrenergic receptor signalling, abnormal cardiomyocyte membrane lipid composition and biophysical properties, ion channel defects and overactivity of humoral cardiodepressant factors. Cirrhotic cardiomyopathy may be difficult to determine due to the lack of a specific diagnosis test. However, an echocardiogram allows the detection of the diastolic dysfunction and the E/e′ ratio may be used in the followup progression of the illness. Cirrhotic cardiomyopathy plays an important role in the pathogenesis of the impairment of effective arterial blood volume and correlates with the degree of liver failure. A clinical consequence of cardiac dysfunction is an inadequate cardiac response in the setting of vascular stress that may result in renal hypoperfusion leading to renal failure. The prognosis is difficult to establish but the severity of diastolic dysfunction may be a marker of mortality risk. Treatment is non-specific and liver transplantation may normalize the cardiac function. | Luís Ruíz-del-árbol Regina Serradilla | 2015 | World Journal of Gastroenterology2015，21，41： | 14 |
| 2 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019，7，17： | 4 |
| 3 | Reconstruction after pancreatoduodenectomy:Pancreatojejunostomy vs pancreatogastrostomy显示文摘Pancreatic surgeons try to find the best technique for reconstruction after pancreatoduodenectomy(PD) in order to decrease postoperative complications,mainly pancreatic fistulas(PF).In this work,we compare the two most frequent techniques of reconstruction after PD,pancreatojejunostomy(PJ) and pancreatogastrostomy(PG),in order to determine which of the two is better.A systematic review of the literature was performed,including major meta-analysis articles,clinical randomized trials,systematic reviews,and retrospective studies.A total of 64 articles were finally included.PJ and PG are usually responsible for most of the postoperative morbidity,mainly due to the onset of PF,being considered a major trigger of life-threatening complications such as intra-abdominal abscess and hemorrhagia.The included systematic reviews reported a significant difference only in the incidence of intraabdominal collections favouring PG.PF,delayed gastric emptying and mortality were not different.Although there was heterogeneity between these studies,all were conducted in specialized centers by highly experienced surgeons,and the surgical care was likely to be similar for all the studies.The disadvantages of PG include an increased incidence of delayed gastric emptying and of main pancreatic duct obstruction due to overgrowth by the gastric mucosa.Exocrine function appears to be worse after PG than after PJ,resulting in severe atrophic changes in the remnant pancreas.Depending on the type of PJ or PG used,the PF rate and other complications can also be different.The best method to deal with the pancreatic stump after PD remains questionable.The choice of method of pancreatic anastomosis could be based on individual experience and on the surgeon's preference and adherence to basic principles such as good exposure and visualization.In conclusion,up to now none of the techniques can be considered superior or be recommended as standard for reconstruction after PD. | Tatiana Gómez Ana Palomares Mario Serradilla Luis Tejedor | 2014 | World Journal of Gastrointestinal Oncology2014，6，9： | 3 |
| 4 | Norfloxacin vs Ceftriaxone in the Prophylaxis of Infections in Patients With Advanced Cirrhosis and Hemorrhage显示文摘 | Javier Fernández Luis Ruiz del Arbol Cristina Gómez Rosa Durandez Regina Serradilla Carlos Guarner Ramón Planas Vicente Arroyo Miguel Navasa | 2006 | Gastroenterology2006，，4： | 2 |
| 5 | A new collabora- tive filtering metric that improves the behavior of recommender sys- tems 显示文摘 | BOBADILLA J SERRADILLA F BERNAL J | 2010 | Knowledge-Based Systems2010，23，6： | 1 |
| 6 | Proealeitonin is not sufficiently reliable to be the sole marker of neonatal sepsis of no-soeomial origin显示文摘 | Lopez Sastre JB Perez Solis D Roques Serradilla V | 2006 | BMC Pediatr2006，6，： | 1 |
| 7 | Diastolic dys- function is a predictor of poor outcomes in patients with cirrho- sis, portal hypertension, and a normal creatinine显示文摘 | Ruz-del-rbol L Achcar L Serradilla R | 2013 | Hepatol- ogy2013，58，5： | 1 |
| 8 | Procalction is not sufficiently reliable to be the sole marker of neonatal sepsis of nosocomial origin显示文摘 | Lopez Sastre J B Perez Solt s D Roques Serradilla V | 2006 | BMC Pediatr2006，18，6： | 1 |
| 9 | Physicochemical and bioactive properties evolution during ripening of 'Ambrun6s' sweet cherry cuhivar显示文摘 | Serradilla M J Lozano M Bernalte M J | 2011 | LWT-Food Science and Technology2011，44，1： | 1 |
| 10 | Goat Acetyl-Coenzyme A Carboxylase α: Molecular Characterization, Polymorphism, and Association with Milk Traits 显示文摘 | Badaoui B Serradilla J M Tombs A | 2007 | J Dairy Sci2007，90，： | 1 |
| 11 | Procalcitonin is not sufficiently realiable to be the soie marker of neonatal sepsis of nosocomialorigin显示文摘 | Lopez Sastre JB Solis DP Serradilla VR | 2006 | BMC Pediatr2006，6，1： | 1 |
| 12 | Identification of Two Polymorphisms in the Goat Lipoprotein Lipase Gene and Their Association with Milk Production Traits 显示文摘 | Badaoui B Serradilla J M Tomas A | 2007 | J Dairy Sci2007，90，： | 1 |
| 13 | Evaluation of procalcitonin for diagnosis of neonatal sepsis of vertical transmission显示文摘 | Lopez Sastre JB Solis DP Serradilla VR | 2007 | BMC Pediotr2007，26，7： | 1 |
| 14 | Antenatal glueocortieoid treatment decreases mortality and chronic lung disease in survivors among 23-to 28- week gestational age preterm infants显示文摘 | Figueras-Aloy J Serrano MM Rodriguez JP Perez CF Serradilla VR Jimenez JQ | 2005 | Am J Perinat2005，22，8： | 1 |
| 15 | Evaluation ofpro- calcitonin for diagnosis of neonatal sepsis of vertical transmission 显示文摘 | L6pez Sastre JB Solis DP Serradilla VR | 2007 | BMC Pedidtr2007，7，： | 1 |
| 16 | Study of microbiological quality of controlled atmosphere packaged 'Ambrun-s' sweet cherries and subsequent she]f-life 显示文摘 | Serradilla M J Villalobos M del C Hemdndez A | 2013 | In- ternational Journal of Food Microbiology2013，166，1： | 1 |
| 17 | Procalcito- nin is not sufficiently reliable to be the sole marker of neonatal sepsis of nosocomial origin显示文摘 | Lopez Sastre JB Perez Solis D Roques Serradilla V | 2006 | BMC Pediatr2006，6，： | 1 |
| 18 | Goat acetyl-coenzyme a carboxylase α: molecular characterization, polymorphism, and association with milk traits 显示文摘 | BADAOUI B SERRADILLA J M TOMAS A | 2007 | Journal of Dairy Science2007，90，2： | 1 |
| 19 | 显示文摘 | SERRADILLA S S POCHET S GROSFILS K | 2003 | Biosens Bioelectron2003，18，2： | 1 |
| 20 | Evaluation of procalcitonin for diagnosis of neonatal sepsis of vertical transmission显示文摘 | López Sastre JB Solís DP Serradilla VR | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员