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| 1 | Chemogenomic data analysis: predic- tion of small - molecule targets and the advent of biological finger print 显示文摘 | Bender A Young DW Jenkins JL Serrano M Mikhailov D Clemons PA Davies JW | 2007 | Comb Chem High Throughput Screen2007，10，8： | 1 |
| 2 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance 显示文摘 | Ling DS Benardo LS Serrano PA | 2002 | Nat Neurosci2002，5，4： | 1 |
| 3 | Synchronous carcinoma of the colon and the rectum (21 cases)显示文摘 | Martín Pérez E Serrano Sánchez PA Larranaga Barrera E | 1992 | Rev Esp Enferm Dig1992，81，6： | 1 |
| 4 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance 显示文摘 | Ling DS Benardo LS Serrano PA | 2002 | Nat Neurosci2002，5，： | 1 |
| 5 | Wallerian degeneration of the corticospinal tract following spontaneous brain haematoma 显示文摘 | Serrano PA Gonzalez JR Castdl MJ | 2005 | Rev Neurol2005，41，： | 1 |
| 6 | Ex vivo gene transer of brain-derived neurotrophic factor to intact rat forebrain: neurotrophic effects on cholinergic neurons显示文摘 | Martinez Serrano A Hantzopoulos PA Bjorkhlund A | 1996 | Eur J Neurosci1996，8，4： | 1 |
| 7 | Presence of and phosphate release from polyphosphates or phytate phosphate in lake sediments 显示文摘 | Golterman H L Paing J Serrano L | 1998 | Hydrobiologia1998，364，1： | 1 |
| 8 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance显示文摘 | Ling DS Benardo LS Serrano PA Blace N Kelly MT Crary JF | 2002 | Nat Neurosci2002，5，4： | 1 |
| 9 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance显示文摘 | Ling DS Benardo IS Serrano PA | 2002 | Nat Neuros- ci2002，5，4： | 1 |
| 10 | Presence of and phosphate release from polyphosphates or phytate phosphate in lake sediments 显示文摘 | Goherman H L Paing J Serrano L | 1998 | Hydrobiologia1998，364，1： | 1 |
| 11 | Esophegeal perforation during gastric bypass:delayed diagnosis and management显示文摘 | Endara SA Serrano AJ Sandoval PA | 2007 | Obes Surg2007，17，7： | 1 |
| 12 | Protein kinase Mzeta is necessary andsufficient for LTP maintenance显示文摘 | Ling DS Benardo LS Serrano PA | | 0，，： | 1 |
| 13 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance显示文摘 | Ling DS Benardo LS Serrano PA | 2002 | Nat Neurosci2002，5，4： | 1 |
| 14 | Presence of and phosphate release from polyphosphates or phytate phosphate in lake sediments显示文摘 | GOLTERMAN H PAING J SERRANO L | 1998 | Hydrobiologia1998，364，： | 1 |
| 15 | Protein kinase is necessary and sufficient for LTP maintenance显示文摘 | Ling DS Benardo LS Serrano PA | 2002 | Nat Neurosci2002，5，4： | 1 |
| 16 | Nonsteroidal anti-inflammatory drug effectivity in preventing postendoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is the primary therapeutic procedure for the treatment of diseases affecting the biliary tree and pancreatic duct.Although the therapeutic success rate of ERCP is high,the procedure can cause complications,such as acute pancreatitis[post-ERCP pancreatitis(PEP)],bleeding and perforation.AIM To assess the efficacy of non-steroidal anti-inflammatory drugs(NSAIDs)in preventing PEP during follow-up.METHODS Databases such as MEDLINE,EMBASE and Cochrane Central Library were searched.Only randomized controlled trials(RCTs)comparing the efficacy of NSAIDs and placebo for the prevention of PEP were included.Outcomes evaluated included the incidence of PEP,severity of pancreatitis,route of administration,types,dose,and timing of administration of NSAIDs.RESULTS Twenty-six RCTs were considered eligible with a total of 8143 patients analyzed.Overall,4020 patients used NSAIDs before ERCP and 4123 did not use NSAIDs(control group).Ultimately,298 cases of post-ERCP acute pancreatitis were diagnosed in the NSAID group and 484 cases in the placebo group.The risk of PEP was lower in the NSAID group risk difference(RD):-0.04;95%confidence interval(CI):-0.07 to-0.03;number needed to treat(NNT),25;P<0.05.NSAID use effectively prevented mild pancreatitis compared to placebo use(2.5%vs 4.1%;95%CI:-0.05 to-0.01;NNT,33;P<0.05),but information on moderate PEP and severe PEP could not be fully elucidated.Only rectal administration reduced the incidence of PEP with RD:-0.06;95%CI:-0.08 to-0.04;NNT,17;P<0.05).Furthermore,only the use of diclofenac or indomethacin was effective in preventing PEP,at a dose of 100 mg,which must be administered before performing ERCP.CONCLUSION Rectal administration of diclofenac and indomethacin significantly reduced the risk of developing mild PEP.Additional RCTs are needed to compare the efficacy between NSAID routes of administration in preventing PEP. | Juan Pablo Román Serrano JoséJukemura Samuel Galante Romanini Paúl Fernando Guamán Aguilar Juliana Silveira Lima de Castro Isabela Trindade Torres JoséAndres Sanchez Pulla Otavio Micelli Neto Eloy Taglieri JoséCelso Ardengh | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，11： | 1 |
| 17 | Wallerian degeneration ofthe corticospinal tract following spontaneous brain baematoma显示文摘 | Serrano PA Conzalez JR Castell MJ | 2005 | Rew Neurol2005，41，： | 1 |
| 18 | Presence of and phosphate release from polyphosphates or phytate phosphate in lake sediments显示文摘 | GOLTERMAN H PAING J SERRANO L | 1998 | Hydrobiologia1998，364，1： | 1 |
| 19 | Endometriosis:the cause of hematuria in the dysfunctional ureter显示文摘 | FERNANDEZ GI SERRANO PA GARCIA CE | 1997 | Arch Esp Urol1997，50，8： | 1 |
| 20 | Protein kinase Mzeta is necessary and sufficient for LTP maintenance 显示文摘 | Ling DS Benardo LS Serrano PA | 2002 | Nat Neurosci2002，5，4： | 1 |
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