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| 1 | Pancreatic exocrine insufficiency, diabetes mellitus and serum nutritional markers after acute pancreatitis显示文摘AIM:To investigate impairment and clinical significance of exocrine and endocrine pancreatic function in patients after acute pancreatitis(AP).METHODS:Patients with AP were invited to participate in the study.Severity of AP was determined by the Atlanta classification and definitions revised in2012.Pancreatic exocrine insufficiency(PEI)was diagnosed by the concentration of fecal elastase-1.An additional work-up,including laboratory testing of serum nutritional markers for determination ofmalnutrition,was offered to all patients with low levels of fecal elastase-1 FE.Hemoglobin A1c or oral glucose tolerance tests were also performed in patients without prior diabetes mellitus,and type 3c diabetes mellitus(T3c DM)was diagnosed according to American Diabetes Association criteria.RESULTS:One hundred patients were included in the study:75%(75/100)of patients had one attack of AP and 25%(25/100)had two or more attacks.The most common etiology was alcohol.Mild,moderately severe and severe AP were present in 67,15 and 18%of patients,respectively.The mean time from attack of AP to inclusion in the study was 2.7 years.PEI was diagnosed in 21%(21/100)of patients and T3c DM in14%(14/100)of patients.In all patients with PEI,at least one serologic nutritional marker was below the lower limit of normal.T3c DM was more frequently present in patients with severe AP(P=0.031),but was also present in some patients with mild and moderately severe AP.PEI was present in all degrees of severity of AP.There were no statistically significantly differences according to gender,etiology and number of AP attacks.CONCLUSION:As exocrine and endocrine pancreatic insufficiency can develop after AP,routine follow-up of patients is necessary,for which serum nutritional panel measurements can be useful. | Miroslav Vujasinovic Bojan Tepes Jana Makuc Sasa Rudolf Jelka Zaletel Tjasa Vidmar Maja Seruga Bostjan Birsa | 2014 | World Journal of Gastroenterology2014，20，48： | 10 |
| 2 | Determination of polyphenols content and antioxidant activity of some red wines by differential pulse voltarnmetry, HPLC and spcctrophommetric methods显示文摘 | v SERUGA M NOVAK I JAKOBEK L | 2010 | Food Chemistry2010，124，3： | 1 |
| 3 | Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients:a systematic review and meta-analysis显示文摘 | Amir E Seruga B Niraula S | 2011 | J Natl Cancer Inst2011，103，17： | 1 |
| 4 | HER3 overex-pression and survival in solid tumors : a meta-analysis 显示文摘 | Ocana A Vera-Badillo F Seruga B | 2013 | JNatl Cancer Inst2013，105，4： | 1 |
| 5 | Chemotherapy-based treatment for castrationresistant prostate cancer显示文摘 | Seruga B Tannock IF | | 0，，27： | 1 |
| 6 | Determination of Thermal Conductivity and Convective Heat Transfer Coefficient During Deep Fat Frying of 'Krostula'Dough显示文摘 | Seruga B Budzaki S | 2005 | Eur Food Res Technol2005，221，： | 1 |
| 7 | Ultrasound extracted flavonoids from four varieties of Portuguese red grape skins determined by reverse - phase high - performance liquid Chromatography with electrochemi- cal detection 显示文摘 | Novak I Janeiro P Seruga M | 2008 | Analytica Chimica Acta2008，630，2： | 1 |
| 8 | Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: a systematic review and meta-analysis显示文摘 | Amir E Seruga B Niraula S | 2011 | J Natl Cancer Inst2011，103，17： | 1 |
| 9 | Effect of Temperaturc and Composition on Thermal Conductivity of'Mlinci'Dough显示文摘 | Seruga B Budzaki S Ugarcic-Hardi Z | 2005 | Czech J Food Sci2005，23，： | 1 |
| 10 | Individual Heat Transfer Modes During Baking of'Mlinci'Dangh显示文摘 | Seruga B Budzaki S Ugarcic-Hardi Z | 2007 | Agriculturae Conspeetus Seientificus2007，72，： | 1 |
| 11 | The price we pay for prog- ress: a meta-analysis of harms of newly approved anticancer drugs 显示文摘 | Niraula S Seruga B Oeana A | 2012 | J Clin Oncol2012，30，24： | 1 |
| 12 | Targeting DNA repair inbreast cancer:a clinical and translational update显示文摘 | Amir E Seruga B Serrano R | 2010 | CancerTreat Rev2010，36，7： | 1 |
| 13 | Aluminium Content of Beers显示文摘 | SERUGA M GRGIC J GRGIC Z | 1997 | European Food Research and Technology1997，，204： | 1 |
| 14 | Cytokines and their relation-ship to the symptoms and outcome of cancer显示文摘 | Seruga B Zhang H Bernstein LJ | 2008 | Nat Rev Cancer2008，8，11： | 1 |
| 15 | Assessing women at high risk of breast cancer:a review of risk assessment models显示文摘 | Amir E Freedman OC Seruga B | | 0，，10： | 1 |
| 16 | Assessing women at high risk of breast cancer : a review of risk assessment models 显示文摘 | AMIR E FREEDMAN O C SERUGA B | 2010 | J Natl Cancer Inst2010，102，10： | 1 |
| 17 | Chemotherapy-based treatment for castration-resistant prostate cancer 显示文摘 | Seruga B Tannock IF | 2011 | J Clin Oneol2011，29，36： | 1 |
| 18 | Cytokines and their re- lationship to the symptoms and outcome of cancer显示文摘 | Seruga B Zhang H Bemstein L J | 2008 | Nat Rev Cancer2008，8，11： | 1 |
| 19 | Assessing women at high risk of breast cancer : a review of risk assessment models 显示文摘 | AMIR E FREEDMAN O C SERUGA B | 2012 | Breast Cancer Res Treat2012，132，10： | 1 |
| 20 | Cytokines and their relation- ship to the symptoms and outcome of cancer 显示文摘 | Seruga B Zhang H Bernstein 13 | 2008 | Nat Rev Cancer2008，8，11： | 1 |
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