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| 1 | Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum显示文摘 | Shak S Capon DJ Hellmiss R | 1990 | Proc Natl Acad Sci USA1990，87，23： | 1 |
| 2 | Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2显示文摘 | Slamon DJ Leyland-Jones B Shak S | 2001 | N Engl J Med2001，344，11： | 1 |
| 3 | Use of chemotherapy plus a monoclonal antibody against I-IER2 for meta- static breast cancer that overexpresses HER2 显示文摘 | SLAMON D J LEYLAND JONES B SHAK S | 2001 | N Engl J Med2001，344，11： | 1 |
| 4 | A multigene assay to predict recur- rence of tamoxifen - treated, node - rlegative breast cancer 显示文摘 | Paik S Shak S Tang G | 2004 | N Engl J Med2004，351，27： | 1 |
| 5 | Gene expression and benefit ofchemotherapy in women with node-negative, estrogen receptor-positive breast cancer 显示文摘 | Paik S Tang G Shak S | 2006 | J Clin Oncol2006，24，23： | 1 |
| 6 | Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that over expresses HER2 显示文摘 | Slamon DJ Leyland Jones B Shak S | 2001 | Englned2001，，： | 1 |
| 7 | Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2显示文摘 | Slamon DJ Leyland-Jones B Shak S | 2001 | N Engl J Med2001，，： | 1 |
| 8 | Gene expression and benefit of chem- otherapy in women with node - negative, estrogen receptor - posi- tive breast cancer显示文摘 | Paik S Tang G Shak S | 2006 | J C lin Onco12006，24，23： | 1 |
| 9 | Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with nodepositive, oestrogen- receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial显示文摘 | Albain KS Barlow WE Shak S | 2010 | Lancet Oncol2010，11，1： | 1 |
| 10 | Prognostic andpredictive value of the 21-gene recurrence score assay inpostmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy : a retrospective analysisof a randomised trial显示文摘 | Albain KS Barlow WE Shak S | 2010 | Lancet Oncol2010，11，1： | 1 |
| 11 | Addition of herceptin (humanized anti-HER2 antibody ) to tirst line chemotherapy for HEP,2 overexpressing metastatic breast cancer ( HER2 +/MBC ) markedly increases anticancer activity: a randomized multinational controlled phase Ⅲ trial 显示文摘 | Slamon D Leyland-Jones B Shak S | 1998 | Proc Am Soc Clin Oncol1998，377，17： | 1 |
| 12 | Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2显示文摘 | Slamon DJ Leyland-Jones B Shak S | 2001 | N Engl J Med2001，344，11： | 1 |
| 13 | Addition of Herceptin to first line chemotherapy for Her- 2 overexpressing metastatic breast cancer (Her-2 +/MBC) markedly increases anti cancer activity:a randomized multinational controlled phase Ⅲ trial 显示文摘 | Slamon D Leyland-Jones B Shak S | 1998 | Proceedings ASCO1998，，： | 1 |
| 14 | Use of chemotherapy plus a monoelonal antibody against HER2 for metastatic breast cancer that overexpreases HER2显示文摘 | Slamon DJ Leyland-Jones B Shak S | | 0，，11： | 1 |
| 15 | A multigene assay to predict recur- rence of tamoxifen treated, node negative breast cancer 显示文摘 | Paik S Shak S Tang G | 2004 | N Engl J Med2004，351，： | 1 |
| 16 | A multigen assay to predict recurrence of tamoxifen-treated,node-negative breast cancer显示文摘 | Paik S Shak S Tang G | 2004 | N Engl J Med2004，351，27： | 1 |
| 17 | A multigene assay to predict recurrence of tamoxifen-t reated, node-negative breast cancer 显示文摘 | Paik S Shak S Tang G | 2004 | N Engl J Med2004，351，： | 1 |
| 18 | Gene expression and benefit of chemotherapy in women with node-negative, estrogen reeeptor-positive breast cancer 显示文摘 | Paik S Tang G Shak S | 2006 | J Clin 0ncol2006，24，23： | 1 |
| 19 | Use of chemotherapy plus a monoclanal antibody against HER2 for metastatic breast cancer that overexpresses HER2显示文摘 | Slamon D J Leyland-Jones B Shak S | 2001 | N Engl J Med2001，344，11： | 1 |
| 20 | Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randonfised trial显示文摘 | Albain KS Barlow WE Shak S | 2010 | Lancet Oncol2010，11，1： | 1 |
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