|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Whole-Genome Resequencing of a Worldwide Collection of Rapeseed Accessions Reveals the Genetic Basis of Ecotype Divergence显示文摘Rapeseed (Brassica napus),an important oilseed crop,has adapted to diverse climate zones and latitudes by forming three main ecotype groups,namely winter,semiwinter,and spring types. However,genetic variations underlying the divergence of these ecotypes are largely unknown. Here,we report the global pattern of genetic polymorphisms in rapeseed determined by resequencing a worldwide collection of 991 germplasm accessions.A total of 5.56 and 5.53 million singlenucleotide polymorphisms (SNPs)as Well as 1.86 and 1.92 million InDels were identified by mapping reads to the reference genomes of 'Darmor-bzh'and 'Tapidor,'respectively.We generated a map of allelic drift paths that shows splits and mixtures of the main populations,and revealed an asymmetric evolution of the two subgenomes of B.napus by calculating the genetic diversity and linkage disequilibrium parameters.Selective-sweep analysis revealed genetic changes in genes orthologous to those regulating various aspects of plant development and response to stresses.A genome-wide association study identified SNPs in the promoter regions of FLOWERING LOCUS T and FLOWERING LOCUS C orthologs that corresponded to the different rapeseed ecotype groups. Our study provides important insights into the genomic footprints of rapeseed evolution and flowering-time divergence among three ecotype groups,and will facilitate screening of molecular markers for accelerating rapeseed breeding. | Dezhi Wu Zhe Liang Tao Yan Ying Xu Lijie Xuan Juan Tang Gang Zhou Ulrike Lohwasser Shuijin Hua Haoyi Wang Xiaoyang Chen Qian Wang Le Zhu Antony Maodzeka Nazim Hussain Zhilan Li Xuming Li Imran Haider Shamsi Ghulam Jilani Linde Wu Hongkun Zheng Guoping Zhang Boulos Chalhoub Lisha Shen Hao Yu Lixi Jiang | 2019 | Molecular Plant2019，12，1： | 10 |
| 2 | Detection of Tocopherol in Oilseed Rape (Brassica napus L.) Using Gas Chromatography with Flame Ionization Detector显示文摘The variation among Chinese genotypes of Brassica napus L.for seed tocopherols content and their analysis using gas chromatography has not been comprehensively reported till to date.In the present study,the tocopherol contents of four Chinese genotypes of Brassica napus L.,namely,Gaoyou 605,Zhejiang 619,Zheshuang 758,and Zheshuang 72,were evaluated using three modified sample preparation protocols(P1,P2,and P3) for tocopherol extraction.These methods were distinguished as follows.Protocol one(P1) included the evaporation of solvent after extraction without silylation.Protocol two(P2) followed the direct supernatant collection after overnight extraction without drying and silylation.Protocol three(P3) included trimethylsilylation with N,O-bis(trimethylsilyl) trifluoroacetamide.Genotypic comparison of tocopherol and its isoforms revealed that Gaoyou 605 was dominant over the other genotypes with(140.5±10.5),(316.2± 9.2),and(559.1±24.3) μg g-1 of seed meal α-,γ-,and total(T-) tocopherol,respectively,and a 0.44±0.04 α-to γ-tocopherol ratio.The comparison of the sample preparation protocols,on the other hand,suggests that P3 is the most suitable method for the tocopherol extraction from Brassica oilseeds and for the analysis of tocopherols using gas chromatography flame ionization detector(GC-FID).Trimethylsilylation is the key step differentiating P3 from P1 and P2.Variations detected in tocopherol contents among the Chinese rapeseed(B.napus) genotypes signify the need to quantify a wide range of rapeseed germplasm for seed tocopherol dynamics in short and crop improvement in long. | Nazim Hussain Zahra Jabeen LI Yuan-long CHEN Ming-xun LI Zhi-lan GUO Wan-li Imran Haider Shamsi CHEN Xiao-yang JIANG Li-xi | 2013 | Journal of Integrative Agriculture2013，12，5： | 6 |
| 3 | Higher frequency of Yq microdeletions in sperm DNA as compared to DNA isolated from blood显示文摘瞄准:决定删除的 Yq 微删除频率和 loci 是否在不同胚胎学的起源的二纸巾(血和精子) 是类似的。方法:现在的学习包括了 52 个不肥沃的 oligozoospermic 盒子。在每种情况中, DNA 从血和精子被孤立,微删除分析从 genomic DNA 被做的聚合酶链反应(PCR ) 从两个孤立纸巾。PCR 产品在 1.8% 统帅玫瑰胶化上被分析。发现否定的 PCR 扩大被重复至少三次证实一个给定的标记的删除。结果:仅仅 1 个盒子在血 DNA 怀有微删除,而 4 个盒子在精子 DNA 怀有微删除。结论:Yq 微删除的频率作为与血相比在细菌房间是更高的。为帮助繁殖生产技术(艺术) 作为不肥沃的夫妇的多数抉择, Yq 微删除从细菌房间屏蔽是重要的理解不孕的基因基础,提供全面建议和大多数改编治疗学给不肥沃的夫妇。 | Rima Dada Rakesh Kumar M. B. Shamsi Rajeev Kumar Kiran Kucheria Raj K. Sharma Satish K. Gupta Narmada P. Gupta | 2007 | Asian Journal of Andrology2007，9，5： | 6 |
| 4 | Interactions of cadmium and aluminum toxicity in their effect on growth and physiological parameters in soybean显示文摘The effect of Al and Cd on the growth, photosynthesis, and accumulation of Al, Cd and plant nutrients in two soybean genotypes were determined using hydroponic culture. There were six treatments: pH 6.5; pH 4.0; pH 6.5+1.0 μmol/L Cd; pH 4.0+1.0 μmol/L Cd; pH 4.0+150 μmol/L Al; pH 4.0+1.0 μmol/L Cd+150 μmol/L Al. The low pH (4.0) and Al treatments caused marked reduction in root length, shoot height, dry weight, chlorophyll content (SPAD value) and photosynthetic rate. Al-sensitive cv. Zhechun 2 accumulated comparatively more Al and Cd in plants than Al-tolerant cv. Liao 1. Compared with pH 6.5, pH 4.0 resulted in significant increase in Cd and Al concentration in plants. Combined application of Cd and Al enhanced their accu-mulation in roots, but caused a reduction in shoots. The concentrations of all 10 nutrients (P, K, Ca, Mg, Fe, Mn, Cu, Zn and B), except Mo were also increased when plants were exposed to pH lower than pH 6.5. Al addition caused a reduction in the con-centration of most nutrients in plant roots and shoots; but K, Mn and Zn in roots were increased. Treatments with Cd alone or together with Al reduced the concentrations of all the plant nutrients in plants. Al-sensitive genotype Zhechun 2 has lower nutrient concentration than Al-tolerant genotype Liao 1. The current findings imply that Al and Cd are synergistic in their effect on plant growth, physiological traits and nutrient uptake. | SHAMSI Imran Haider JILANI Ghulam | 2007 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2007，8，3： | 5 |
| 5 | 陕西省神木县几种气象因素对儿童下呼吸道感染发生的影响显示文摘目的评价陕西省神木县气象因素与儿童下呼吸道感染住院人数的关系。方法收集2009年1月至2012年12月神木县气象因素(气温、气压、降雨量、光照时间、风速和相对湿度)及≤16岁儿童的住院资料。利用SAS9.3对气象、下呼吸道感染住院人数、总住院人数和下呼吸道感染住院率进行描述性分析。了解各气象因素与下呼吸道感染住院率之间的相关程度,并探讨气象因素与下呼吸道感染住院率之间相关性。结果纳入研究的对象19772例,其中下呼吸道感染住院患者4449例,占22.5%。下呼吸道感染住院率与气温(r=-0.651,P〈0.001)、气压(r=0.560,P〈0.001)、降雨量(r:-0.614,P〈0.001)和相对湿度(r=-0.470,P〈0.001)呈显著相关,而与光照强度、风速无相关性。多重线性回归分析发现,下呼吸道感染住院率随着平均气温和平均湿度的上升而逐渐下降(F=38.30、15.58,P均〈O.001)。结论平均气温和平均湿度是影响神木县儿童下呼吸道感染住院率的主要气象因素。 | 刘永林 刘娟 陈凤莲 BILAL HAIDER Shamsi 王强 焦富勇 乔艳梅 史彦华 | 2014 | 中华实用儿科临床杂志2014，29，16： | 4 |
| 6 | 神木市医院住院患儿20年疾病谱变迁分析显示文摘目的 了解神木市医院住院患儿疾病谱及病死率的变化趋势,为今后该地区儿童疾病诊疗、预防保健工作及医疗资源配置提供科学依据.方法 回顾性分析神木市医院儿科1998年1月1日至2017年12月31日出院患儿的病案资料病历信息,包括疾病种类、构成比、性别、年龄、出院主要诊断、入院时间、出院时间、出院转归等资料,分析其疾病谱构成及流行病学特征.采用SPSS 17.0软件进行统计学分析,计数资料采用χ2检验;计量资料采用非参数Kruskal-Wallis秩和检验.结果 1998年至2017年,儿科14岁及以下的住院患儿共45 554例,其中男31 345例,占68.9%.年龄多集中于婴儿期(29 d^1岁),占36.2%.患儿平均住院天数5.84 d,中位时间5 d.呼吸系统疾病在疾病系统构成中始终居于首位(构成比60.0%).之后位次依次是新生儿疾病(19.8%)、消化系统疾病(10.7%)、神经系统疾病(2.6%)、传染病(2.2%).死亡患儿共182例,病死率有逐年下降的趋势(χ2=109 189.66,P<0.01).死亡患儿罹患的前5位疾病分别为早产儿、新生儿窒息、新生儿呼吸窘迫综合征、新生儿肺炎、肺炎.结论 20年间儿科住院病例疾病谱发生了明显的变化,常见病、多发病的防治仍是儿科临床及预防工作的重点,与此同时对逐年增长的疾病给予足够的重视. | 刘娟 刘永林 BILAL HAIDEN Shamsi | 2018 | 中华实用儿科临床杂志2018，33，23： | 4 |
| 7 | Diabetic macular edema:New promising therapies显示文摘The treatment of diabetic macular edema is rapidly evolving.The era of laser therapy is being quickly replaced by an era of pharmacotherapy.Several pharmacotherapies have been recently developed for the treatment of retinal vascular diseases such as diabetic macular edema.Several intravitreal injections or sustained delivery devices have undergone phase 3 testing while others are currently being evaluated.The results of clinical trials have shown the superiority of some of these agents to laser therapy.However,with the availability of several of these newer agents,it may be difficult to individualize treatment options especially those patients respond differently to various therapies.As such,more effort is still needed in order to determine the best treatment regimen for a given patient.In this article,we briefly summarize the major new therapeutic additions for the treatment of diabetic macular edema and allude to some future promising therapies. | Hanan N Al Shamsi Jluwi S Masaud Nicola G Ghazi | 2013 | World Journal of Diabetes2013，4，6： | 4 |
| 8 | CLCNKB基因突变致巴特综合征1例报告及文献复习显示文摘1962年Bartter等因首先报道了2例非裔美国人[1]有代谢性碱中毒、醛固酮增多症、肾小球旁器增生等异常表现,而得名巴特综合征([2]Bartter’ssyndrome,BS)。它是一种遗传性肾小管疾病,主要表现为低钠血症、低钾血症、代谢性碱中毒、高肾素血症,而血压正常或偏低[3]。BS的主要发病机制是髓袢升支粗段上参与Nacl重吸收的转运蛋白功能缺陷,即Na-K-2Cl协同转运蛋白(NKCC2)、顶端钾离子通道(ROMK)或基底外侧氯离子通道(CLCNKB)[4]缺陷。该病是一种常染色体隐性遗传病,多年来,一些表型和基因型变异的BS已被确认[5]。笔者医院确诊1例CLCNKB基因突变所致巴特综合征,现报告如下。 | 刘永林 刘瑞 Bilal Haider Shamsi | 2021 | 中国实用儿科杂志2021，36，8： | 3 |
| 9 | Synergistic interaction of NaCl and Cd on growth and photosynthetic parameters in soybean genotypes differing in salinity tolerance显示文摘The effects of salinity(50 mmol/L NaCl) and Cd(1 μmol/L CdCl2) as sole and combined on growth and photosyn-thetic parameters were studied using two soybean genotypes,Huachun 18 and NGB.The concentrations of Cd2+,Zn2+,Ca2+,Mg2+,K+ and Na+ were also determined in seeds and pods.Huachun 18 suffered a more serious decrease than NGB in net photosynthetic rate(Pn) in the treatments of salinity stress alone and combined stress(NaCl+Cd),showing that it is relatively sensitive to salinity.The decrease in Pn caused by salt stress in Huachun 18 was mainly due to the reduced total chlorophyll content and photosynthetic efficiency(the ratio of variable fluorescence to maximal fluorescence,Fv/Fm),whereas the decease in NGB was mainly related to reduced stomatal conductance(Gs).The combined stress of both Na and Cd did not induce further decrease in photosynthesis and fluorescence in the two genotypes relative to salt or Cd stress alone.Greater change in the pod concentrations of Zn2+,Ca2+,Mg2+,K+ and Na+ was detected under salt stress for Huachun 18 than for NGB.The results suggested that the interactive effect of NaCl-Cd on growth and nutrient uptake differs between the two soybean genotypes. | SHAMSI Imran Haider | 2007 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2007，8，4： | 3 |
| 10 | 煤矿区大气污染与儿童呼吸道疾病住院人数的时间序列分析显示文摘目的评价神木县大气污染与儿童呼吸道感染住院人数的关系。方法收集2009年11月至2012年10月间神木县的气象因素(气温、相对湿度)和环境因素:二氧化硫(SO_2)、二氧化氮(NO_2)和可吸入颗粒物(PM10),以及16岁及以下儿童的住院资料。利用SAS 9.3对气象、环境因素和住院人数资料进行描述性分析,并判断主要污染物。利用R 3.0.1统计软件的建立Poisson回归的广义相加模型,引入大气污染物浓度及气象因素拟合线性模型,并考虑其滞后效应,评价主要大气污染物对儿童呼吸道感染住院的相对危险度。结果神木县的首要污染物为PM10,PM10与空气污染指数(API)的相关系数为0.917,P<0.01。在控制了长期趋势、'星期几效应'、气象因素及其它污染物的影响后发现,首要大气污染物PM10浓度每上升10μg/m^3时,每日呼吸道感染住院患儿的上呼吸道相对危险度(RR)及其95%可信区间(95%CI)为1.002(0.996~1.007),t=0.589,P=0.556;下呼吸道为1.000(0.995~1.005),t=-0.007,P=0.995。当日或滞后1~10日内PM10浓度变化均不能显著改变儿童上、下呼吸道感染的住院率。结论神木县首要污染物PM10浓度变化对儿童上、下呼吸道感染的住院情况无明显影响。 | 刘永林 刘娟 陈凤莲 张耀文 史彦华 BILAL HAIDER Shamsi 王强 焦富勇 乔艳梅 | 2014 | 中国妇幼健康研究2014，25，4： | 3 |
| 11 | 茉莉酸对油菜(Brassica napus L.)受镉毒害的缓解作用(英文)显示文摘目的:本研究目的在于了解:(1)喷施外源茉莉酸对受到镉胁迫油菜的作用;(2)是否茉莉酸能够通过增强气体交换,从而保护受到氧化胁迫的地上部分组织的叶绿体,进而通过减少镉的吸收来维持离子平衡;(3)是否通过喷施茉莉酸来对具有减缓镉毒害效应的抗氧化酶的活性进行调节。创新点:茉莉酸能够调节响应胁迫的抗氧化酶的活性,从而通过保护叶绿体免受活性氧(ROS)伤害而提高光合产物的能力,最大限度地缓解油菜植株受到的镉毒害。方法:(1)叶片气体交换;(2)叶片光合色素分析;(3)丙二醛与抗氧化酶活性分析;(4)营养成分分析;(5)透射电镜亚细胞水平观察。结论:茉莉酸对于植物受镉毒害的缓解作用的机理在于减少叶片中镉的积累,从而减轻氧化胁迫过程中产生的ROS对于膜系统的损害程度。 | Essa ALI Nazim HUSSAIN Imran Haider SHAMSI Zahra JABEEN Muzammil Hussain SIDDIQUI Li-xi JIANG | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，2： | 2 |
| 12 | Alleviation of arsenic toxicity by phosphate is associated with its regulation of detoxification,defense,and transport gene expression in barley显示文摘Arsenic(As) contamination in soils has posed a severe threat to safe crop production. The previous studies showed the antagonism between phosphorus(P) and As in plant growth and As uptake, while the mechanisms of alleviating As toxicity by P is not completely clear. Due to the limiting P condition, it is imperative to understand how low P addition can be used to suppress arsenate As(V) uptake and the subsequent mechanisms involved. Thus in this study we investigated the effect of P addition on As uptake, anti-oxidative enzyme activity, and anti-oxidant content, and the relative expression of transport, defense, and detoxification genes using two barley genotypes differing in As toxicity tolerance. P addition significantly reduced As concentration in plant tissues, and caused the great changes in activities of catalase and superoxide dismutase, glutathione content, and the relative expression of examined genes when the plants of the two barley genotypes were exposed to 100 μmol L^(–1) As, with ZDB160(As-tolerant) being much more affected than ZDB475(As-sensitive). The current results show that P addition can alleviate As toxicity by regulating the expression of As transport, defense, and detoxification genes to a greater extent in As tolerance of barley, suggesting the possibility of controlling As uptake and toxicity by applying low amount of P fertilizers in the As-contaminated soils. | Gerald Zvobgo Jonas Lwalaba Wa Lwalaba Tichaona Sagonda James Mutemachani Mapodzeke Noor Muhammad Imran Haider Shamsi ZHANG Guo-ping | 2019 | Journal of Integrative Agriculture2019，18，2： | 2 |
| 13 | Outcomes of surgical management of tracheobronchial injuries a case series from a developing country显示文摘客观 Tracheobronchial 损害被定义为从延长直到支气管的部门的环状的软骨的水平包含气管或支气管的损害。我们在场有大多数 tracheobronchial 损害的一个盒子系列发现了在渗透损伤以后被支撑。回顾的评论在统帅中亚细亚大学被执行的方法,喀拉蚩,巴基斯坦。从 2004 年 1 月到 2009 年 12 月,有胸的损伤的 168 个病人被对待,谁 15 被认出有主要 tracheobronchial 和肺的损害。结果平均年龄是与大多数是男性的病人(14:1 ) 一起的 31 年。在他们之中, 11 个病人让了作为损害的主要原因渗透损伤,有的 3 个病人从道路交通事故弄钝损伤,仅仅 1 个病人联合了损伤(钝、渗透的损伤) 。八个病人基于放射学的调查结果被诊断。所有病人通过手术被对待。叶切除术是在 7 个病人执行的最普通的干预。死亡率是 7%(1 个病人) 。当 5 与残疾幸存时,大多数病人没有 sequelae (10 个病人) 幸存。我们发现渗透损伤是在我们的系列的损害的领先的原因。损害的严厉取决于引起损伤的武器。在我们的系列的病人有多重损害并且要求了外科的管理。结论 Tracheobronchial 损害是稀罕的但是潜在地威胁的生活。他们要求快诊断和管理。自从没有目前可得到的专业化诊断形式,诊断趋于困难。 | Saulat H. Fatimi Hashim M. Hanif Ameera Ahmed Ghina Shamsi Marium Muzaffar | 2011 | Chinese Journal of Traumatology2011，14，3： | 2 |
| 14 | 巴基斯坦高校创业教育探究--一项教师视角的案例研究显示文摘作为一个发展中国家,巴基斯坦面临着贫穷、失业等诸多问题,关注高校创业教育并给予实践,鼓励和引导创业,将极大地促进就业率,为发展巴基斯坦国家经济做出巨大贡献。此研究以巴基斯坦两所高校的教师为研究对象,希望通过对巴基斯坦的旁遮普大学和白沙瓦大学的创业教育调研来进一步认识巴基斯坦高校创业教育的现状。目前巴基斯坦高校创业教育存在着诸如体制不均衡、课程改革滞后等问题,提升巴基斯坦创业教育水平需要政府和高校的共同努力。 | Iffat Batool 徐小洲 Imran Haider Shamsi 孙杨 李娜 | 2015 | 现代大学教育2015，31，4： | 2 |
| 15 | 锌和硅对2种水稻基因型的镉毒害及矿质元素转移的影响(英文)显示文摘为探究在镉(Cd)胁迫处理下锌(Zn)和硅(Si)对水稻中矿质元素从根到地上部转移的长期影响,以水稻耐镉基因型秀水110和镉敏感基因型HIPJ 1为供试材料,设置8个处理组合:3个Si处理水平(0,5,15μmol/L Na_2Si O_3·9H_2O)、3个Zn处理水平(0,1,10μmol/L Zn SO_4·7H_2O)和2个Cd处理水平(0,15μmol/L Cd Cl_2),测定其植株生物量、光合强度、抗氧化酶活性、脂质过氧化强度和矿质元素浓度。结果显示,Si(15μmol/L)或Zn(10μmol/L)可有效缓解Cd(15μmol/L)毒害对水稻植株生长的抑制效应,且以Zn的缓解效果更好。在Cd(15μmol/L)胁迫下添加Si(15μmol/L)或Zn(10μmol/L)可有效降低2个水稻基因型叶片中的丙二醛含量,并增强两者叶片中的过氧化氢酶活性,且以在秀水110中的效果更好。单一Zn或Si处理和Zn-Si复合处理均可减少HIPJ 1中的Cd^(2+)从根至地上部的转运。此外,Cd能显著降低水稻植株体内Ca、Mn、Mg等矿质元素的转运。单一Zn处理能够显著促进植物生长,且效果好于单一Si处理与Zn-Si联合处理。但是Zn-Si复合处理对提高Cd胁迫下矿质元素的吸收效果并不显著。 | MAPODZEKE James Mutemachani SAGONDA Tichaona SEHAR Shafaque 张欣 黄雨晴 ZVOBGO Gerald MAODZEKA Antony LWALABA WA LWALABA Jonas SHAMSI Imran Haider | 2018 | 浙江大学学报(农业与生命科学版)2018，44，3： | 2 |
| 16 | Nitrogen losses from tops of three rice varieties grown in nutrient culture solution显示文摘 | ASHRAF M SHAMSI S R A SAJJAD M I | 1997 | Pakistan J Bot1997，29，： | 1 |
| 17 | A novel missense Norrie diseasemutation associated with a severe ocular phenotype 显示文摘 | Khan AO Shamsi FA AL-Saif A | 2004 | J Pediatr Oph-thalmol Strabismus2004，41，6： | 1 |
| 18 | Shear bond strength and residual adhesive after orthodontic bracket debonding 显示文摘 | Al Shamsi A Cunningham JL Lamey PJ | 2006 | Angle Orthod2006，76，4： | 1 |
| 19 | Superparamagnetic iron oxide particles (SHU555A): evaluation of efficacy in three doses for hepatic MR imaging显示文摘 | Shamsi K Balzer T Saini S | 1998 | Radiology1998，206，2： | 1 |
| 20 | Attenuation of oxidative stress & DNA damage in varicocelectomy: implications in infertility management显示文摘 | Dada R Shamsi MB Venkatesh S | 2010 | Indian J Med Res2010，132，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员