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| 1 | Population-based study of DNA image cytometry as screening method for esophageal cancer显示文摘AIM:To explore the DNA image cytometry (DNA-ICM) technique as a primary screening method for esopha-geal squamous precancerous lesions.METHODS:This study was designed as a population-based screening study.A total of 582 local residents aged 40 years-69 years were recruited from Linzhou in Henan and Feicheng in Shandong.However,only 452 subjects had results of liquid-based cytology,DNA-ICM and pathology.The sensitivity and specificity of DNA-ICM were calculated and compared with liquid-based cytology in moderate dysplasia or worse.RESULTS:Sensitivities of DNA-ICM ranging from at least 1 to 4 aneuploid cells were 90.91%,86.36%,79.55% and 77.27%,respectively,which were better than that of liquid-based cytology (75%).Specifici-ties of DNA-ICM were 70.83%,84.07%,92.65% and 96.81%,but the specificity of liquid-based cytology was 91.91%.The sensitivity and specificity of a combination of liquid-based cytology and DNA-ICM were 84.09% and 85.78%,respectively.CONCLUSION:It is possible to use DNA-ICM tech-nique as a primary screening method for esophageal squamous precancerous lesions. | Lin Zhao,Wen-Qiang Wei,Xin-Qing Li,Guo-Qing Wang,Qi Shang,You-Lin Qiao,Department of Cancer Epidemiology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China De-Li Zhao,Department of Epidemiology,Feicheng People’s Hospital,Feicheng 271600,Shandong Province,China Chang-Qing Hao,Department of Endoscopy,Linzhou Cancer Hospital,Linzhou 456500,Henan Province,China Dong-Mei Lin,Qin-Jing Pan,Department of Pathology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China Fu-Hua Lei,Department of Pathology,Feicheng People’s Hospi-tal,Feicheng 271600,Shandong Province,China Jin-Wu Wang,Department of Pathology,Linzhou Cancer Hospi-tal,Linzhou 456500,Henan Province,China | 2012 | World Journal of Gastroenterology2012，18，4： | 15 |
| 2 | Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one- compound peptide libraries显示文摘one-bead-one-compound (OBOC ) 组合的肽图书馆是一个强大的工具识别 ligand 和受体相互作用。这里,我们使用了 OBOC 图书馆技术识别对主要贝壳变应原 tropomyosin 的免疫球蛋白 E (IgE ) epitopes 特定的 mimotopes。有 8-12 氨基酸残余的 OBOC 肽图书馆为 tropomyosin 的 IgE mimotopes 与贝壳过敏症从病人与浆液样品被屏蔽。25 mimotopes 从屏蔽被识别,他们到 tropomyosin 特定的 IgE 的有约束力的反应被肽 ELISA 证实。这些 mimotopes 能基于顺序相同被划分成七簇,并且由聚类的 mimotopes 的 EpiSearch 印射的 epitope 被执行描绘并且证实 mimotopes 的有效性。五从六预言的 epitopes 被发现与 tropomyosin 的以前识别的 epitopes 重叠。为了推进,证实 mimotopes 的模仿潜力, BALB/c 老鼠被使免疫, mimotopes 结合了到锁眼恋栈者 hemocyanin 和 assayed 让他们的能力导致 tropomyosin 特定的抗体。那收到的 mimotope 免疫被发现有 tropomyosin 特定的免疫球蛋白 G 的提高的水平的 BALB/c 老鼠,然而并非收到了无关的 mimotope 的老鼠。这研究用整个 sera 开创 OBOC 图书馆的成功的申请屏蔽并且识别多重虾变应原 mimotopes 并且验证他们在 vitro 使用的模仿潜力,在 vivo,并且在 silico 方法。 | Nicki YH Leung Christine YY Wai Marco HK Ho Ruiwu Liu Kit S Lam Jin Jun Wang Shang An Shu Ka Hou Chu Patrick SC Leung | 2017 | Cellular & Molecular Immunology2017，14，3： | 6 |
| 3 | A new navigation approach of terrain contour matching based on 3-D terrain reconstruction from onboard image sequence显示文摘This article presents a passive navigation method of terrain contour matching by reconstructing the 3-D terrain from the image sequence(acquired by the onboard camera).To achieve automation and simultaneity of the image sequence processing for navigation,a correspondence registration method based on control points tracking is proposed which tracks the sparse control points through the whole image sequence and uses them as correspondence in the relation geometry solution.Besides,a key frame selection method based on the images overlapping ratio and intersecting angles is explored,thereafter the requirement for the camera system configuration is provided.The proposed method also includes an optimal local homography estimating algorithm according to the control points,which helps correctly predict points to be matched and their speed corresponding.Consequently,the real-time 3-D terrain of the trajectory thus reconstructed is matched with the referenced terrain map,and the result of which provides navigating information.The digital simulation experiment and the real image based experiment have verified the proposed method. | LI LiChun1,2,YU QiFeng2,SHANG Yang2,YUAN Yun2,LU HongWei3 & LIU XiaoLin4 1 Beijing Aerospace Control Center,Beijing 100094,China 2 College of Aerospace and Material Engineering,National University of Defense Technology,Changsha 410073,China 3 Equipment Research Institute of PLA’s Second Artillery,Beijing 100085,China 4 College of Mechatronic Engineering and Automation,National University of Defense Technology,Changsha 410073,China | 2010 | Science China(Technological Sciences)2010，53，5： | 5 |
| 4 | 等离子体激励器在航空航天工程中的应用前景显示文摘文章基于等离子体的Joule加热、静电力、Hall效应以及Lorentz加速度等固有特性,对等离子体在航空航天领域(不包括电推进和飞行器再入热防护方面)中的应用进行总结及评估.等离子体激励器在亚声速流到高超声速流的整个空气动力学领域及稀薄流领域,得到了广泛的应用.真正引人瞩目的是,与所控制的流场相比,应用中所加入的电磁力或能量仅仅与其扰动水平相当.因此,有效的流动控制往往就限制在像流动分离、流体动力学不稳定性、动态失速和涡破碎等动力学分岔问题中.有效的控制应用通常是利用有黏-无黏流相互作用的放大效应、外部磁场或微波能量的加入等来增强其控制效果.最后文章根据这些评估,对未来学科前沿提出了几点基础创新研究方向的建议. | SHANG Joseph J S 严红 刘凡 | 2018 | 气体物理2018，3，2： | 3 |
| 5 | Hypersonic Experimental Facility for Magnetoaerodynamic Interactions显示文摘 | Shang J S Kimmel R Hayes J | 2005 | Journal of Spacecraft and Rockets2005，42，5： | 1 |
| 6 | Soil nutrient factors related to salidroside production of rhodiola sachalinensis distributed in chang bai mountain显示文摘 | YAN X F WU S X WANG Y SHANG X H DAI S J | 2004 | Environmental and Experimental Botsny2004，52，： | 1 |
| 7 | Detection of bacterial DNA by PCR and reverse hybridization in the 16S rRNA gene with particular reference to neonatal septicemia显示文摘 | Shang S Chen Z Yu X | 2001 | Aeta Paediatr2001，90，2： | 1 |
| 8 | Effect of Zr addition on the microstructure and properties of Cu - 10Cr in situ Composites 显示文摘 | DENG J Q ZHANG X Q SHANG S Z | 2009 | Materials and Design2009，30，： | 1 |
| 9 | Physical properties of silk fibroin/ cellulose blend films regenerated from the hydrophilic ionic liquid显示文摘 | Shang S Zhu L Fan J | 2011 | Carbohydrate Polymers2011，86，2： | 1 |
| 10 | CH4-CO2 reforming by plasma-challenges and opportunities显示文摘 | TAO X M BAI M G LI X LONG H L SHANG S Y YIN Y X DAI X Y | | 0，，02： | 1 |
| 11 | A biomass-supported Na2CO3 sorbent for flue gas desulfurization显示文摘 | Shang H S Ti O Y Fan Y | | 0，，： | 1 |
| 12 | Lattice Dynamics, Ther- modynamics and Elastic Properties of Monoclinic Li2 CO3 from Den- sity Functional Theory 显示文摘 | Shang S L Hector L G Shi S Q | 2012 | Acta Mater2012，60，： | 1 |
| 13 | High expression of DEK predicts poor prognosis of gastric adenocarcinoma 显示文摘 | Piao J Shang Y Liu S | 2014 | Diagn Pathol2014，9，： | 1 |
| 14 | Collaborative filtering with diffusion-based similarity on tripartite graphs显示文摘 | Shang M S Zhang Z K Zhou T | 2010 | Physi- ca A: Statistical Mechanics and Its Applications2010，389，6： | 1 |
| 15 | Regeneration of full-scale commercial honeycomb monolith catalyst(V2O5-WO3/Ti O2)used in coal-fired power plant显示文摘 | SHANG X S HU G R HE C | 2012 | J Ind Eng Chem2012，18，51： | 1 |
| 16 | Total gaseous mercury in the atmosphere of Guiyang, PR China 显示文摘 | Feng X Tang S Shang L | 2003 | Science of the Total Environment2003，304，： | 1 |
| 17 | Characterization and biodegradability of amphoteric superabsorbent polymers显示文摘 | Wang D Song Z Q Shang S 13 | 2008 | J Appl Polym Sci2008，107，6： | 1 |
| 18 | Simulation of water dynamics and irrigation scheduling for winter Wheat and Maize in seasonal frost areas显示文摘 | Shang S H Li X C Mao X M | 2004 | Agriculture Water Management2004，68，2： | 1 |
| 19 | A fast and efficientheuristic algorithm for detecting communitystructures in complex networks显示文摘 | Chen D B Fu Y Shang M S | 2009 | Physica A2009，388，： | 1 |
| 20 | Adaptive wavelet thresholding for Emage denoising and compression显示文摘 | Shang S G Yu B Vetterli M | 2000 | lEEE Transactions onImage Processing2000，9，9： | 1 |
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