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| 1 | 男性性功能障碍、男性不育与神经系统疾病之间的关系显示文摘正常的性功能和生殖功能很大程度上依赖于神经系统功能的正常发挥。男性神经系统受损可导致勃起功能障碍、射精障碍和精液异常,进而导致不育。出现这些受损的主要原因有盆腔和腹腔损伤、糖尿病、先天性脊柱异常,多发性硬化症和脊髓受损。勃起功能障碍已经可以通过越来越具侵入式的治疗方法而有所改善,从药物疗法、注射疗法到外科的阴茎植入术。病情较轻的逆行射精患者可以用药物来逆转条件进行治疗,对病情较重的患者,则在射精后从其膀胱中收取精液。对于中度的不射精者,可以采用药物治疗:而对于严重者,则可采用阴茎震荡刺激和电射精等辅助射精技术。假如这些措施都失败了,可尝试采用手术方法取精液。对于一些脊髓受损的男性,假如环境条件和精液质量足够好,可在家中采用阴茎震荡刺激,然后将精液放入伴侣阴道内。其他方法就要求助于辅助生殖技术了,包括宫内受精和体外受精(用ICSI或者不用)。选用何种方法在很大程度上依赖于患者精液中活性精子的数量。 | Mikkel Fode Sheila Krogh-Jespersen Nancy L Brackett Dana A Ohl Charles M Lynne Jens Sonksen | 2012 | Asian Journal of Andrology2012，14，1： | 7 |
| 2 | Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis显示文摘Systemic corticosteroids represent the standard treatment for autoimmune pancreatitis with IgG4-associated cholangitis.For steroid-dependent disease,azathioprine has been used for maintenance of remission.Mycophenolate mofetil has been used for transplant immunosuppression and more recently for autoimmune hepatitis;however,there are no case reports to date on the use of mycophenolate mofetil in adult patients with autoimmune pancreatitis.A patient with IgG4-mediated autoimmune pancreatitis and IgG4-associated cholangitis refractory to steroids and intolerant of azathioprine was treated with mycophenolate mofetil,which inhibits de novo guanosine synthesis and blockade of both B and T lymphocyte production.Introduction of mycophenolate mofetil and uptitration to 1000 mg by mouth twice daily over a treatment period of 4 mo was associated with improvement in the patient's energy level and blood glucose control and was not associated with any adverse events.The patient was managed without a biliary stent.However,there was a return of symptoms,jaundice,increase in transaminases,and hyperbilirubinemia when the prednisone dose reached 11 mg per day.In the first report of mycophenolate mofetil use in an adult patient with IgG4-associated autoimmune pancreatitis and IgG4-associated cholangitis,the introduction of mycophenolate mofetil was safe and well-tolerated without adverse events,but it did not enable discontinuation of the steroids.Mycophenolate mofetil and other immunomodulatory therapies should continue to be studied for maintenance of remission in the large subset of patients with refractory or recurrent autoimmune pancreatitis. | Jamie B Sodikoff Steven A Keilin Sheila J Bharmal Melinda M Lewis Gottumukkala S Raju Field F Willingham | 2012 | World Journal of Gastroenterology2012，18，18： | 6 |
| 3 | Male gametophyte development显示文摘 | SHEILA M | 1993 | The Plant Cell1993，10，5： | 1 |
| 4 | Olive oil phenolicsprotect LDL and spare vitamin E in the hamster 显示文摘 | Sheila A WisemanB Tijburg M | 2002 | Lipids2002，37，11： | 1 |
| 5 | A form of albinism in cattle is caused by a tyrosinase frameshift mutation显示文摘 | Sheila M Schmutz Tom G Berryere Daniel C Ciobanu | 2004 | Mammalian Genome2004，15，： | 1 |
| 6 | Calcification resistance with aluminium-ethanol treated porcine aortic valve bioprostheses in juvenile sheep显示文摘 | Matthew F Ogle M Sheila J | 2003 | Ann Thorac Surg2003，75，6： | 1 |
| 7 | Sustainability, Clusters, and Competitiveness 显示文摘 | Sheila M Heike M | 2008 | Economic Development Quarterly2008，，22： | 1 |
| 8 | Identification of a point mutation associated with pyrethroid resistance in the para -type sodium channel of Triatoma infestans , a vector of Chagas’ disease显示文摘 | Jésica Fabro Marcos Sterkel Natalia Capriotti Gastón Mougabure-Cueto Mónica Germano Rolando Rivera-Pomar Sheila Ons | 2011 | Infection, Genetics and Evolution2011，，2： | 1 |
| 9 | Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia显示文摘 | Michelle M Le B Sheila B | 2002 | Blood2002，99，8： | 1 |
| 10 | A form of albinism in cattle is caused by a tyrosinase frameshift mutation 显示文摘 | SHEILA M S TOM G B DANIEL C C | 2004 | MammalianGenome2004，15，： | 1 |
| 11 | Diagnosing insulin resistance in the general population 显示文摘 | Kirsten AM Sheila MW Jim I M | 2001 | Diabetes Care2001，24，： | 1 |
| 12 | Collagenase induced intrac- erebral hemorrhage in rats 显示文摘 | Gary A Rosenberg M D Sheila M B | 1990 | Stroke1990，21，6： | 1 |
| 13 | Dependence of stimulated Brillouin scattering in multimode fibers on beam quality,pulse duration,and coherence length显示文摘 | Lopez Q M Sheila G Sverker H | 2003 | Journal of Optical Society of America B2003，20，3： | 1 |
| 14 | Adapting parentchild interaction therapy for young children with separation anxiety disorder显示文摘 | Donna B Pincus Sheila M Eyberg Molly L Choate | 2005 | Education and Treatment of Children2005，28，2： | 1 |
| 15 | Impact of highly and less job-related diversity on work group cohesion and performance: a meta-analysis显示文摘 | Sheila Simsarian Webber Lisa M Donahue | 2001 | Journal of Management2001，，2： | 1 |
| 16 | The influence of erbium: yttrium-aluminum-garnet laser ablation with variable pulse width on morphology and microleakage of composite restorations显示文摘 | Ricardo SN Sheila GS Alessandra C et M | 2010 | Lasers Med Sci2010，25，： | 1 |
| 17 | Outcomes of Parent-Child Interaction Therapy : A Comparison of Treatment Completers and Study Dropouts One to Three Years Later 显示文摘 | Boggs Stephen R Eybert Sheila M Edwards Daniel L | 2005 | Child and Family Behavior Therapy2005，26，4： | 1 |
| 18 | Outcomes of parent-child interaction therapy: mothers' s reports of maintenance three to six years after treatment显示文摘 | Korey K Hood Sheila M Eyberg | 2003 | J clinical child and adolescent psychology2003，32，3： | 1 |
| 19 | Evaluation of waist circumference, waist-to-hip ratio, and the conicity index as screening tools for high trunk fat mass ,as measured by dual-energy X-ray absorptiometry in ehildren aged 3-19 y显示文摘 | Rachael W T Ianthe E J Sheila M W | 2000 | Am J Clin Nutr2000，72，： | 1 |
| 20 | Cebulactams A1 and A2, new maerolaetams isolated from Saccharopolyspora cebuensis, the first obligate marine strain of the genus Saccharopolyspora 显示文摘 | Sheila Marie P E Tobias A M Gulderb Hentschel U | 2008 | Tetrahedron Letters2008，49，48： | 1 |
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