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| 1 | Mesenchymal stem cells: Molecular characteristics and clinical applications显示文摘Mesenchymal stem cells (MSCs) are non-hematopoietic stem cells with the capacity to differentiate into tissues of both mesenchymal and non-mesenchymal origin. MSCs can differentiate into osteoblastic, chondrogenic, and adipogenic lineages, although recent studies have demonstrated that MSCs are also able to differentiate into other lineages, including neuronal and cardiomyogenic lineages. Since their original isolation from the bone marrow, MSCs have been successfully harvested from many other tissues. Their ease of isolation and ex vivo expansion combined with their immunoprivileged nature has made these cells popular candidates for stem cell therapies. These cells have the potential to alter disease pathophysiology through many modalities including cytokine secretion, capacity to differentiate along various lineages, immune modulation and direct cell-cell interaction with diseased tissue. Here we first review basic features of MSC biology including MSC characteristics in culture, homing mechanisms, differentiation capabilities and immune modulation. We then highlight some in vivo and clinical evidence supporting the therapeutic roles of MSCs and their uses in orthopedic, autoimmune, and ischemic disorders. | Farbod Rastegar Deana Shenaq Eric R Wagner Stephanie H Kim Russell R Reid Hue H Luu Rex C Haydon | 2010 | World Journal of Stem Cells2010，2，4： | 35 |
| 2 | Prefabricated flaps:experimental and clinical review显示文摘 | SHENAQ S M SPIRA M | 1995 | Plast Reconstr Surg1995，96，5： | 1 |
| 3 | Mesenchymal progenitor cells and their orthopedic applications: forging a path towards clinical trials 显示文摘 | Shenaq DS Rastegar F Petkovic D | 2010 | Stem Cells Int2010，2010，： | 1 |
| 4 | The role of soft tissue reconstruction after melanoma resection in the head and neck 显示文摘 | Bogle M Kelly P Shenaq J | 2001 | Head Neck2001，23，1： | 1 |
| 5 | The role of soft tissue reconstruction after melanoma resection in the head and eck显示文摘 | Bogle M Kelly P Shenaq J | 2001 | Head Neck2001，23，： | 1 |
| 6 | Role of RANK-RANKL-OPG axis in cranial suture homeostasis显示文摘 | Lee JC Spiguel L Shenaq DS | | 0，，02： | 1 |
| 7 | Mesenchymal progenitor cells and their orthopedic applications:forging a path towards clinical trials显示文摘 | Shenaq D Rastegar F Petkovic D | | 0，，： | 1 |
| 8 | New research in breast reconstruction: adipose tissue engineering显示文摘 | Shenaq S M Yuksel E | 2002 | Clin Plast Surg2002，29，： | 1 |
| 9 | Role of RANK - RANKL - OPG axis in cranial suture homeostasis 显示文摘 | Lee JC Spiguel L Shenaq DS | 2011 | J Craniofac Surg2011，22，2： | 1 |
| 10 | An anatomical, morphological and electrophysiological study of the rabbit facial nerve in the temporal bone显示文摘 | Ozcan G Shenaq S Spira M | 1993 | Eur Arch Otorhinolaryngol1993，249，8： | 1 |
| 11 | A new vascularized nerve graft model in the rabbit显示文摘 | Ozcan G Shenaq S Spira M | | 0，，1： | 1 |
| 12 | Gene therapy for plastic and reconstructive surgery显示文摘 | Shenaq SM Rabinovsky ED | 1996 | Clin Plast Surg1996，23，1： | 1 |
| 13 | Nerve regeneration in a bony bed: vascularized versus nonvascularized nerve grafts 显示文摘 | Ozcan G Shenaq S Mirabi B | 1993 | Plastic and Reconstructive Surgery1993，91，： | 1 |
| 14 | Fluticasone furoate nasal spray reduces the nasal-ocular reflex:a mechanism for the efficacy of topical steroids in controlling allergic eye symptoms显示文摘 | Baroody FM Shenaq D DeTineo M | 2009 | J Allergy Clin Immunol2009，123，6： | 1 |
| 15 | Gene therapy for plastic and reconstructive surgery J显示文摘 | Shenaq SM Rabinovsky ED | 1996 | Clin Plast Surg1996，23，1： | 1 |
| 16 | Neuronal damage and functional deficits are ameliorated by inhibition of aqua porin and HIF-1a after traumatic brain injury(TBI)显示文摘 | Shenaq M Kassem H Peng C | 2012 | J Neurol Sci2012，323，12： | 1 |
| 17 | Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIFla after traumatic brain injury (TBl)显示文摘 | Shenaq M Kassem H Peng C | 2012 | J Neurol Sci2012，323，： | 1 |
| 18 | 135: Body Contouring in the Post-Bariatric Surgery Patient显示文摘 | Shenaq DS Agarwal S Teven C | 2011 | Plast Reconstr Surg2011，127，： | 1 |
| 19 | Paraplegia following aortic surgery 显示文摘 | Shenaq SA Svensson L G | 1993 | J Cardiothorac Vasc Anesth1993，7，： | 1 |
| 20 | New research in breast reconstruction:adipose tissue engineer显示文摘 | Shenaq SM Yuksel E | 2002 | Clin Plast Surg2002，29，1： | 1 |
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