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| 1 | Microstructure and Properties of W-Cu Alloys Prepared with Mechanically Activated Powder显示文摘W-15% Cu (mass fraction) alloys were sintered with mechanically activated powder in order to develop new preparing processes and improve properties of alloys. The microstructures of the activated powder and the sintered alloy were observed. Properties such as density were measured. The results show that through mechanical activation, the particle size of the powder becomes finer to sub-micron or nanometer level, some copper was soluble in tungsten, and high density W-Cu alloys can be obtained by mechanically activated powder for its action to the activation sintering. | Chengchang Jia, Xiuhu Guan, Xuekuan Su, Changheng Hou, Shimin Fan, Jun Zhao, Zizhang Xie (Material Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China) (Beijing Research Institute of Powder Metallurgy, Beiji | 2001 | Journal of University of Science and Technology Beijing2001，8，2： | 5 |
| 2 | Preclinical evaluation and pilot clinical study of [^(18)F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts显示文摘In recent years,fibroblast activation protein(FAP)has emerged as an attractive target for the diagnosis and radiotherapy of cancers using FAP-specific radioligands.Herein,we aimed to design a novel^(18)Flabeled FAP tracer([^(18)F]Al F-P-FAPI)for FAP imaging and evaluated its potential for clinical application.The[^(18)F]Al F-P-FAPI novel tracer was prepared in an automated manner within 42 min with a non-decay corrected radiochemical yield of 32±6%(n=8).Among A549-FAP cells,[^(18)F]Al F-P-FAPI demonstrated specific uptake,rapid internalization,and low cellular efflux.Compared to the patent tracer[^(18)F]FAPI-42,[^(18)F]Al F-P-FAPI exhibited lower levels of cellular efflux in the A549-FAP cells and higher stability in vivo.Micro-PET imaging in the A549-FAP tumor model indicated higher specific tumor uptake of[^(18)F]Al F-P-FAPI(7.0±1.0%ID/g)compared to patent tracers[^(18)F]FAPI-42(3.2±0.6%ID/g)and[68 Ga]Ga-FAPI-04(2.7±0.5%ID/g).Furthermore,in an initial diagnostic application in a patient with nasopharyngeal cancer,[^(18)F]Al F-P-FAPI and[^(18)F]FDG PET/CT showed comparable results for both primary tumors and lymph node metastases.These results suggest that[^(18)F]Al F-P-FAPI can be conveniently prepared,with promising characteristics in the preclinical evaluation.The feasibility of FAP imaging was demonstrated using PET studies. | Kongzhen Hu Junqi Li Lijuan Wang Yong Huang Li Li Shimin Ye Yanjiang Han Shun Huang Hubing Wu Jin Su Ganghua Tang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 4 |
| 3 | Active and stable Cu doped NiMgAlO catalysts for upgrading ethanol to n-butanol显示文摘Upgrading ethanol to n-butanol is an attractive way for renewable n-butanol production. Herein, Cu was selected to modify NiMgAlO catalysts for improving ethanol conversion and n-butanol selectivity. Over the optimized 2%Cu-NiMgAlO catalyst, ethanol conversion and n-butanol selectivity were enhanced to 30.0% and 64.2%, respectively, in 200 h time on stream at 523 K. According to physicochemical characterizations and theoretical calculations, the key role of multiple active sites in this reaction was extensively investigated. The plate-like structure of hydrotalcite was maintained over 2%Cu-NiMgAlO catalysts, with an average Ni particle size of ca. 5.4 nm. The presence of Cu species created CuNi alloy sites and Lewis acid-base pairs, and increased hydrogen transfer and condensation reactions, resulting in elevated ethanol conversion and n-butanol selectivity. Additionally, CuNi alloy had a strong interaction with CuNiMgAl oxides, forming homogeneous boundary due to their close ionic radius and lattice matching, and afforded the long time stability in the ethanol to n-butanol reaction. | Zhinuo Wang Ming Yin Jifeng Pang Xianquan Li Yanan Xing Yang Su Shimin Liu Xiaoyan Liu Pengfei Wu Mingyuan Zheng Tao Zhang | 2022 | Journal of Energy Chemistry2022，31，9： | 2 |
| 4 | Profitability Regulation, Earnings Management and Modified Audit Opinions 显示文摘 | CHEN CHARLES J P CHEN SHIMIN SU XIJIA | 2001 | Auditing : A Journal of Practice and Theory2001，，20： | 1 |
| 5 | Profitability Regulation,Earnings Management and Modified Audit Opinions显示文摘 | Chen Charles J.P Chen Shimin Su Xijia | | 0，，： | 1 |
| 6 | Thermal stability and flammability of Polyamide 66/montmorillonite nanoeomposites 显示文摘 | Huaili Qin Quansheng Su Shimin Zhang | 2003 | Polymer2003，44，： | 1 |
| 7 | Thermal sta- bility and flammability of polyamide 66/montmorillonite nano- composites 显示文摘 | Qin Huaili Su Quansheng Zhang Shimin | 2003 | Polymer2003，44，24： | 1 |
| 8 | Thermal stability and flammability of polyamide 66/montmorillonite nanocomposites显示文摘 | Huaili Qin Quansheng Su Shimin Zhang | 2003 | Polymer2003，44，24： | 1 |
| 9 | Profitability Regulation, Earnings Management,and Modified Audit Opinions:Evidence from China显示文摘 | Charles J P Chen Shimin Chen Xijia Su | 2001 | Auditing:A Journal of Practice & Theory2001，20，2： | 1 |
| 10 | Melt Blending of Polypropylene-Blend- Polyamide 6-Blend-Organoclay Systems 显示文摘 | Quansheng Su Meng Feng Shimin Zhang | 2007 | Polymer International2007，56，1： | 1 |
| 11 | Inverse kinematic analysis of the general 6R serial manipulators based on double quaternions显示文摘 | Shuguang Qiao Qizheng Liao Shimin Wei Hai-Jun Su | 2009 | Mechanism and Machine Theory2009，，2： | 1 |
| 12 | Thermal stability and flammability of polyamide 66/montmorillonite nanocomposites显示文摘 | Qin Huaili Su Quansheng Zhang Shimin | 2003 | Polymer2003，，44： | 1 |
| 13 | Profitability Regulation, Earnings Management and Modified Audit Opinions显示文摘 | CHEN CHARLES J P CHEN SHIMIN SU XIJIA | 2001 | Auditing: A Journal of Practice and Theory2001，，20： | 1 |
| 14 | Thermal stability and flammability of polyamide 66/montmorillonite nanocomposites显示文摘 | Huaili Qin Quansheng Su Shimin Zhang | 2003 | Polymer2003，，44： | 1 |
| 15 | An Analysis of Auditing Environment and Modified Audit Opinions in China : Underlying Reasons and Lessons 显示文摘 | Chen Shimin Xijia Su and Zhenglin Wang | 2005 | International Journal of Auditing2005，，： | 1 |
| 16 | Thermal stability and flammability of polyamide 66/montmorillonite nanocomposites显示文摘 | Huaili Qin Quansheng Su Shimin Zhang | 2003 | Polymer2003，44，24： | 1 |
| 17 | Thermal stability and flammability of polyamide 66/montmorillonite nanocomposites显示文摘 | Huaili Qin Quansheng Su Shimin Zhang | 2003 | Polymer2003，44，： | 1 |
| 18 | Thermal Stability and Flammability of Polyamide 66/Montmorillonite显示文摘 | Huaili Qin Quanshelag Su Shimin Zhang | 2003 | Pdymer2003，44，24： | 1 |
| 19 | Profitability regulation, earnings management and modified audit opinions evidence from China 显示文摘 | Chen J P Chen Shimin Su Xijia | 2001 | Auditing : A Journal of Practice and Theory2001，，2： | 1 |
| 20 | Profitability Regulation,Earnings Management and Modified Audit Opinions 显示文摘 | CHEN CHARLES J P CHEN SHIMIN SU XIJIA | 2001 | Auditing : A Journal of Practice and Theory2001，20，2： | 1 |
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