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| 1 | Cellulosomes: structure arid ultrastructure显示文摘 | Bayer E A Shimon L J W Lamed R | 1998 | J Struct Biol1998，124，： | 1 |
| 2 | Cellulosomes-Structure and Ultrastructure显示文摘 | Bayer E A Shimon L J W Shoham Y Lamed R | 1998 | J Struct Biol1998，124，： | 1 |
| 3 | A cohesin domain from Clostridium thermocellum: the crystal structure provides new insights into cellulosome assembly显示文摘 | Shimon LJ Bayer E A Morag E Lamed R Yaron S Shoham Y Frolow F | 1997 | Structure1997，5，： | 1 |
| 4 | Naturally arising Foxp3-expressing CD25+CD4+,regulatory T cells in immunological tolerance to self and non-self显示文摘 | Sakaguchi S Shimon R | 2005 | Nature Immunology2005，6，4： | 1 |
| 5 | Plant growth-promoting bacteria confer resistance in tomato plants to salt stress显示文摘 | Shimon Mayak Tsipora Tirosh Bernard R Glick | 2004 | Plant Physiology and Biochemistry2004，42，： | 1 |
| 6 | Nitrate assimilation in plant shoots depends on photorespiration 显示文摘 | Shimon R Asaph B C Arnold J B | 2004 | PNAS2004，101，11： | 1 |
| 7 | Tandem pinacol coupling-rearrangement of aromatic aldehydes with hydrogen catalyzed by a combination of a platinum com- plex and a polyoxometalate显示文摘 | Branytska O Shimon L J W Neumann R | 2007 | Chemical Communications2007，38，： | 1 |
| 8 | Managing by Values : Cultural Redesign for Strategic Organizational Change At the Dawn of the Twenty - first Century 显示文摘 | Shimon L Dolan Salvador R Garcia | 2002 | Journal of Management Development2002，21，2： | 1 |
| 9 | Global carbon sequestration in tidal, saline wedand soils 显示文摘 | Gall L Chmura Shimon C Anisfeld Donald R Cahoon | 2003 | Global Biogeoehemieal Cycles2003，17，： | 1 |
| 10 | Plant growth-promoting bacteria that confer resistance to water stress in tomatoes and peppers显示文摘 | Shimon M Tsipora T Bernard R G | 2004 | Plant Science2004，166，： | 1 |
| 11 | Plant growth-promoting bacteria confer resistance in tomato plants to salt stress显示文摘 | Shimon M T Bernard R G | 2004 | Plant Physiology and Biochemistry2004，42，： | 1 |
| 12 | Determination of phenoliccompounds in olives by reversed-phase chromatographyand mass spectrometry显示文摘 | Danielle R Kevin R Shimon L | 1999 | J Chromatogr A1999，832，： | 1 |
| 13 | Determination of phenolic compounds in olives by reversed-phase chromatography and mass spectrometry 显示文摘 | DANIELLE R KEVIN R SHIMON L | 1999 | J Chrom A1999，832，： | 1 |
| 14 | Liquid chromatography with electrospray ionisation mass spectrometric detection of phenolic compounds from Olea europaea 显示文摘 | DANIELLE R KEVIN R SHIMON L | 1999 | J Chrom A1999，855，： | 1 |
| 15 | New ligand system based on a bipyridine-functionalized calix arene backbone leading to monoand bimetallic complexes显示文摘 | Dorta R Shimon L J W Rozenberg H | 2003 | Inorg Chem2003，42，： | 1 |
| 16 | Recognition by Linear Combination of Models显示文摘 | Ullman Shimon R Basil | 1991 | IEEE Trans on Pattern Analysis and Machine Intelligence1991，13，10： | 1 |
| 17 | Fos expression in rat visual cortex induced by ocular input of ultraviolet light 显示文摘 | SHIMON A BARRY R | 1996 | Brain Research1996，716，： | 1 |
| 18 | Successful treatment of acute relapse of chronic eosinophilic pneumonia with benralizumab and without corticosteroids:A case report显示文摘BACKGROUND Currently,the mainstay of chronic eosinophilic pneumonia(CEP)treatment is corticosteroids,usually with a favorable response and good prognosis.However,relapse is common,requiring long-term use of corticosteroids,with risk of significant treatment-related complications.The dire need to develop new treatments for patients with CEP,who are dependent on,or resistant to corticosteroids has led to exploring novel therapies.We herein describe a patient with acute relapse of CEP,who was successfully treated with benralizumab,an IL-5 Rαantagonist that has demonstrated rapid anti-eosinophil action in patients with asthma.Currently,only three recent patient reports on CEP relapse,also demonstrated successful treatment with benralizumab alone,without corticosteroids.CASE SUMMARY A 31-year-old non-smoking woman presented in our hospital with a 3 wk history of shortness of breath,dry cough and fever up to 38.3℃.Laboratory examination revealed leukocytosis 10240 K/μL,eosinophilia 900 K/μL and normal values of hemoglobin,platelets,creatinine and liver enzymes.Computed tomography of the chest showed a mediastinal lymphadenopathy and consolidations in the right upper and left lower lobes.CEP was diagnosed,and the patient was treated with hydrocortisone intravenously,followed by oral prednisone,with prompt improvement.Three months later,she presented with relapse of CEP:aggravation of dyspnea,rising of eosinophilia and extension of pulmonary infiltrates on chest X-ray.She was treated with benralizumab only,with clinical improvement within 2 wk,and complete resolution of lung infiltrates following 5 wk.CONCLUSION Due to Benralizumab’s dual mechanism of action,it both neutralizes IL-5 Rαpro-eosinophil functions and triggers apoptosis of eosinophils.We therefore maintain benralizumab can serve as a reasonable therapy choice for every patient with chronic eosinophilic pneumonia and a good alternative for corticosteroids. | Shimon Izhakian Barak Pertzov Dror Rosengarten Mordechai R Kramer | 2022 | World Journal of Clinical Cases2022，10，18： | 0 |
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