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6篇 您的检索式:作者名="Shiyan Pan"
    题名 作者 年代 出处 被引量
1Automatic 3D segmentation of the liver from abdominal CT images: A level-set approach显示文摘Shiyan Pan Benoit M Dawant 2001Medical Imaging: Image Processing Proceedings of SPIE2001,4322,:1
2Lattice Boltzmann modeling of dendritic growth in a forced melt convection显示文摘Dongke Sun Mingfang Zhu Shiyan Pan Dierk Raabe 2008Acta Materialia2008,,6:1
3Numeri- cal Simulation of Microstructure Evolution During Alloy So- lidification by Using Cellular Automaton Method显示文摘ZHU Mingfang PAN Shiyan SUN Doongke 2010ISIJ In- ternational2010,50,12:1
4Nodeless superconducting gaps in Ca10(Pt(4-δ)As8)((Fe(1-x)Ptx)2As2)5 probed by quasiparticle heat transport显示文摘The in-plane thermal conductivity of the iron-based superconductor Ca10(Pt_(4-δ)As_8)((Fe_(1-x)Pt_x)_2As_2)_5 single crystal('10-4-8', T c= 22 K) was measured down to 80 m K. In a zero field, the residual linear term κ_0/T is negligible, suggesting the nodeless superconducting gaps in this multiband compound. In the magnetic fields, κ_0/T increases rapidly, which mimics the multiband superconductor Nb Se_2 and Lu Ni_2B_2 C with highly anisotropic gap. Such a field dependence of κ_0/T is an evidence for the multiple superconducting gaps with quite different magnitudes or highly anisotropic gap. Compared with the London penetration depth results of the Ca10(Pt_(4-δ)As_8)((Fe_(1-x)Pt_x)_2As_2)_5('10-3-8') compound, the 10-4-8 and 10-3-8 compounds may have a similar superconducting gap structure.Xun Qiu LanPo He XiaoChen Hong ZhenZhang Jian Pan XiaoPing Shen DongLai Feng ShiYan Li 2016Science China(Physics,Mechanics & Astronomy)2016,59,5:0
5Correlation between Microstructures and Yield Strength of a High Strength Enameling Steel显示文摘Numerical estimates of the components of yield strength of a high strength Fe-C-Mn-P-N-Si enameling steel were determined using empirical relationships between microstructure and yield strength. Results are reported for both the hot rolled (HR) and cold rolled (CR) forms before and after simulating an enamel-fire anneal (EFA). To determine the solubilities of alloying elements, thermodynamic calculations were performed in combination with the considerations of process conditions and the element diffusivities. The results show that the main solid solution strengtheners were the elements Mn, Si, and P, while the elements C and N were nearly completely tied up as precipitates. The yield strength reduction, due to the EFA, resulted primarily from an increase in grain size and a decrease in dislocation density, and the EFA appeared to have a negligible effect on the element solubilities.Ming Jiang Xuefeng Yang Shiyan Pan Bruce W.Krakauer Mingfang Zhu 2012Journal of Materials Science & Technology2012,28,8:0
6Cell membrane-coated mesoporous silica nanorods overcome sequential drug delivery barriers against colorectal cancer显示文摘Local delivery of nanomedicines holds therapeutic promise for colorectal cancer(CRC).However,it presents tremendous challenges due to the existence of multiple physiological barriers,especially intracellular obstacles,including intracellular trafficking,subcellular accumulation,and drug release.Herein,we report a multifunctional nanoparticle(CMSNR)by wrapping the mesoporous silica nanorod with cell membrane derived from CRC cells for improved chemotherapy.Compared with their naked counterparts,the cell membrane endowed CMSNR with homotypic targeting and improved cellular uptake capacities.Due to the rod-like shape,CMSNR achieved superior colorectal mucus permeability,enhanced tumor accumulation,and boosted cellular uptake than their spherical counterparts.Moreover,the internalized CMSNR underwent robust intracellular trafficking and gained augmented motility toward the nucleus,leading to efficient perinuclear accumulation and a subsequent 5.6-fold higher nuclear accumulation of loaded drug than that of nanospheres.In the orthotopic colorectal tumor-bearing nude mice,rectally administrated mefuparib hydrochloride(MPH)-loaded CMSNR traversed the colorectal mucus,penetrated the tumor tissue,and successfully aggregated in the perinuclear region of cancer cells,thus exhibiting significantly improved antitumor outcomes.Our findings highlight the shape-based design of cell membranecoated nanoparticles that can address sequential drug delivery barriers has a promising future in cancer nanomedicine.Jie Wang Hao Pan Jingyi Li Di Nie Yan Zhuo Yishan Lv Ning Wang Hao Chen Shiyan Guo Yong Gan Xinggang Yang Miaorong Yu 2023Chinese Chemical Letters2023,34,6:0
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