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| 1 | Testicular defense systems: immune privilege and innate immunity显示文摘因为它显著有免疫力的特权和有效本地天生的免疫的性质,哺乳动物的睾丸拥有特殊免疫学的环境。阴囊的有免疫力的特权保护产生免疫性的细菌房间免受全身的有免疫力的攻击的伤害,并且本地天生的免疫在阻止阴囊的微生物引起的感染是重要的。本地阴囊的有免疫力的动态平衡的故障可以导致睾丸炎,男不孕的一个 etiological 因素。位于阴囊的有免疫力的特权下面的机制很长时间被调查了。增加的证据两个都显示出那本地抑制免疫力的周围和全身的有免疫力的忍耐涉及维持阴囊的有免疫力的特权地位。位于阴囊的天生的免疫下面的机制基于模式识别的调查正在出现在阴囊的房间的调停受体的天生的有免疫力的反应。这评论总结我们阴囊的防卫机制的当前的理解并且鉴别应得的话题推进调查。 | Shutao Zhao Weiwei Zhu Shepu Xue Daishu Han | 2014 | Cellular & Molecular Immunology2014，11，5： | 10 |
| 2 | Sanders' Mid-long Cylindrical Shell Theory and its Application to Ocean Engineering Structures显示文摘The cylindrical shell is one of the main structural parts in ocean engineering structures.These cylinders are mostly of medium length,which means that the radius of the cross section is significantly smaller than the length of the cylindrical shell.From the viewpoint of the shell theory,they belong to the mid-long cylindrical shell category.To solve mechanical problems on this kind of structure,especially a cracked cylindrical shell,analysis based on shell theory is necessary.At present the generally used solving system for the mid-long cylindrical shell is too complicated,difficult to solve,and inapplicable to engineering.This paper introduced the Sanders' mid-long cylindrical shell theory which reduces the difficulty of the solution process,and will be suitable for solving problems with complicated boundary conditions.On this basis,the engineering applications of this theory were discussed in conjunction with the problem of a mid-long cylindrical shell having a circumferential crack.The solution process is simple,and the closed form solution can usually be found.In practical engineering applications,it gives satisfactory precision. | Shutao He (1) heshutao6105@163.com Yao Zhao (1) | 2012 | Journal of Marine Science and Application2012，11，1： | 3 |
| 3 | Control system for cryogenic permanent magnet undulator(CPMU)of high energy photon source(HEPS)显示文摘Background High energy photon source(HEPS)is the fourth-generation light source,which uses a large number of highperformance insertion devices to generate synchrotron radiation.The control system is an important part of the insertion device(ID).Purpose Cryogenic permanent magnet undulator(CPMU)is one kind of IDs that works in liquid nitrogen temperature and ultra-high vacuum environment,and its control system is more difficult and complex than in-air ID.The design of the control system for CPMU will be introduced in detail.Method The sub-systems include high-precision magnetic gap control,safety protection,measurement and compensation of magnetic gap at cryogenic temperature and cryogenic temperature monitoring.Mature,reliable,stable technical schemes are designed to meet the technical specifications of sub-systems.Results The experiment results show that the magnetic gap motion accuracy can be controlled within 0.2–0.3μm under the step size of 1μm.The safety protection system has been tested in turn,and the predetermined protection can be achieved.The average value of magnetic gap cold contraction is 1.512 mm measured by optical micrometer,and the compensation is realized by software.The average temperature of the main magnet structure measured by the temperature sensors is 81.0 K,and the temperature gradient is 0.7 K/m.The temperature monitoring is reliable and stable.Conclusion The CPMU control system which is based on EPICS has been successfully applied to the CPMU prototype,and the test results have met the design specifications. | Shutao Zhao Jianshe Cao Huihua Lu Xiaoyu Li Shuchen Sun Yajun Sun Xiangzhen Zhang Lei Zhang Yuhui Li Zhiqiang Li Wan Chen Lingling Gong Qing Guo Keyun Gong Yongsheng Huang Yanwei Yang Yufeng Yang | 2021 | Radiation Detection Technology and Methods2021，5，1： | 2 |
| 4 | Acute ZnO nanoparticles exposure induces developmental toxicity, oxidative stress and DNA damage in embryo-larval zebrafish显示文摘 | Xuesong Zhao Shutao Wang Yuan Wu Hong You Lina Lv | 2013 | Aquatic Toxicology2013，，： | 2 |
| 5 | Mechanical design of a cryogenic Delta-Knot undulator for high energy photon source显示文摘Introduction A novel type of pure permanent cryogenic Delta–Knot Undulator was developed at IHEP to supply a high flux of full adjustable polarization synchrotron radiation with low on-axis power density.This prototype was an active attempt and early exploration for future APPLE–Knot undulator,which will be used at high energy photon source(HEPS).Materials and methods There are several challenges to develop a cryogenic delta undulator,such as the complicated structure,the influence of large magnetic force,and the magnetic measurement difficulty due to the very small gap.In this paper,the mechanical design for overcoming these difficulties will be presented in detail.Conclusion A special hall measuring system is developed,and the preliminary results agree with the theoretical results.This undulator prototype will provide valuable experience for angle magnetization technology,intricate magnetic attraction structure design,and magnetic field measurement under closed small space. | Shuchen Sun Huihua Lu Xiaoyu Li Xiangzhen Zhang Yanwei Yang Yajun Sun Lei Zhang Yuhui Li Zhiqiang Li Wan Chen Lingling Gong Shutao Zhao Qing Guo Keyun Gong Yongsheng Huang Yufeng Yang | 2021 | Radiation Detection Technology and Methods2021，5，1： | 1 |
| 6 | Extreme points and rotundity of Orlicz-Sobolev spaces显示文摘 | Chen Shutao Hu Changying Charles Xuejin Zhao | 2002 | Inter J Math Math Sci2002，32，5： | 1 |
| 7 | Image inpainting with salient structure completion and texture propagation显示文摘 | Li Shutao Zhao Ming | | 0，，： | 1 |
| 8 | Uniform rotundity of Orlicz-Sobolev spaces显示文摘 | Chen Shutao Hu Changying Charles Xuejin Zhao | 2003 | Soochow J Math2003，29，3： | 1 |
| 9 | NbCl5 as an Efficient Catalyst for Chemoselective Synthesis of 1,1-diacetates Under Solvent-free Conditions显示文摘 | GAO Shutao ZHAO Ying LI Chao | 2009 | Synth Commun2009，39，： | 1 |
| 10 | Text detection in images using sparse representation with discriminative dictionaries 显示文摘 | ZHAO Ming LI Shutao KWOK J | 2010 | Image and Vision Computing2010，28，12： | 1 |
| 11 | Image inpainting with salient structure completion and texture propagation显示文摘 | Li Shutao Zhao Ming | | 0，，： | 1 |
| 12 | Production of very-high-amylose cassava by post-transcriptional silencing of branching enzyme genes显示文摘High amylose starch can be produced by plants deficient in the function of branching enzymes(BEs).Here we report the production of transgenic cassava(Manihot esculenta Crantz)with starches containing up to 50%amylose due to the constitutive expression of hair-pin ds RNAs targeting the BE1 or BE2 genes.All BE1-RNAi plant lines(BE1i)and BE2-RNAi plant lines(BE2i)were grown up in the field,but with reduced total biomass production.Considerably high amylose content in the storage roots of BE2i plant lines was achieved.Storage starch granules of BE1i and BE2i plants had similar morphology as wild type(WT),however,the size of BE1i starch granules were bigger than that of WT.Comparisons of amylograms and thermograms of all three sources of storage starches revealed dramatic changes to the pasting properties and a higher melting temperature for BE2i starches.Glucan chain length distribution analysis showed a slight increase in chains of DP>36 in BE1i lines and a dramatic increase in glucan chains between DP 10-20 and DP>40 in BE2i lines.Furthermore,BE2i starches displayed a B-type X-ray diffraction pattern instead of the A-type pattern found in BE1i and WT starches.Therefore,cassava BE1 and BE2 function differently in storage root starch biosynthesis. | Wenzhi Zhou Shanshan Zhao Shutao He Qiuxiang Ma Xinlu Lu Xiaomeng Hao Hongxia Wang Jun Yang Peng Zhang | 2020 | Journal of Integrative Plant Biology2020，62，6： | 1 |
| 13 | Uniform rotundity of Orlicz-Sobolev spaces显示文摘 | Chen Shutao Hu Changying Cherles Zhao Xuejin | 2003 | Soochow J of Math2003，29，3： | 1 |
| 14 | Text detection in images using sparse representation with discriminative dictionaries显示文摘 | ZHAO Ming LI Shutao Kwok J | 2010 | Image and Vision Computing2010，28，12： | 1 |
| 15 | Distinct roles of the IRE1αarm and PERK arm of unfolded protein response in arachidonic acid-induced ferroptosis in hepatocytes显示文摘Ferroptosis is a distinct form of cell death that is driven by iron-dependent phospholipid peroxidation.Polyunsaturated fatty acids(PUFAs),particularly arachidonic acid(AA)and adrenal acid(AdA),are most prone to lipid peroxidation,which induces ferroptosis and affects the function of cell membranes.In this study,we discovered that AA induces ferritinophagy in hepatocytes,a selective form of autophagy that degrades ferritin,triggering unstable iron overload.Mechanistically,AA enhances cellular uptake of bound iron by up-regulating transferrin receptor 1(TfR1).Additionally,AA induces endoplasmic reticulum stress(ER stress)and simultaneously activates two of its branches,pancreatic ER kinase(PERK)and inositol-requiring enzyme 1(IRE1).Notably,PERK and IRE1 appear to play distinct roles in inducing ferritinophagy.Inhibition of PERK reduced the AA-induced increase of Fe^(2+)by alleviating ferritinophagy,while inhibition of IRE1 further exacerbated ferroptosis by activating ferritinophagy.Furthermore,there seems to be an interaction between the signaling pathways of ER stress,and inhibition of IRE1 exacerbates AA-induced ferritinophagy by further activating the PERK signaling pathway,thereby exacerbating the extent of cell death.Collectively,our findings suggest that iron overload is involved in AA-induced hepatocyte ferroptosis and that this process is regulated by ER stress-mediated ferritinophagy.This study suggests potential therapeutic strategies for treating liver diseases related to lipid metabolism disorders by intervening in the ferroptosis process. | Han Zhang Kai Han Shutao Yin Lihong Fan Hongbo Hu Chong Zhao | 2023 | Food Innovation and Advances2023，2，3： | 0 |
| 16 | Redox deracemization of α-substituted 1,3-dihydroisobenzofurans显示文摘Chiralα-substituted 1,3-dihydroisobenzofurans are key scaffolds in a number of bioactive natural products and synthetic pharmaceuticals.However,catalytic asymmetric approaches have been rarely developed.Here,a redox deracemization technology is adopted to address the catalytic asymmetric synthesis.A broad range ofα-aryl substituted 1,3-dihydroisobenzofurans are effectively deracemized in high efficiency with excellent ee.α-Alkynyl substituted ethers were also compatible with the deracemization technology. | Xiaohan Chen Ran Zhao Ziqiang Liu Shutao Sun Yingang Ma Qingyun Liu Xia Sun Lei Liu | 2021 | Chinese Chemical Letters2021，32，7： | 0 |
| 17 | Thermal Decomposition Kinetics and Mechanism ofLow-temperature Hydrogenated Acrylonitrile Butadiene Rubber Composites with Sodium Methacrylate显示文摘Thermal decomposition processes and mechanism of low-temperature grade hydrogenated acrylonitrilebutadiene rubber(LTG-HNBR) composites with sodium methacrylate(NaMAA) were investigated by thermogravime-tric analysis(TGA) and Fourier transform infrared spectroscopy(FTIR) coupling technology in this article. The resultsof TGA demonstrate that the addition of NaMAA can enhance the thermal decomposition temperature of the rubber.Moreover, it was found that the composites spent more activation energies to decompose than pure rubber by thecalculations of multiply heating rate method. Time-resolved FTIR spectra show that NaMAA affects the initial de-composition of the composites. But in the following process, the composites maintained a similar behavior to the ma-trix. During the decomposition, PNaMAA nanostructures, in-situ generated by NaMAA, helped reduce the diffusionspeed of decomposition products and thus improved the thermal stability of the composites. | ZHANG Jihua LI Jie LIU MinNie ZHAO Yunfeng WANG Shutao | 2016 | Chemical Research in Chinese Universities2016，32，6： | 0 |
| 18 | Diversity and association analysis of important agricultural trait based on miniature inverted-repeat transposable element specific marker in Brassica napus L.显示文摘Miniature inverted-repeat transposable elements(MITEs)are a group of DNA transposable element(TE)which preferentially distributed with gene associated regions.Tens of MITEs families have been revealed in Brassica napus genome,they scatter across the genome with tens of thousands copies and produce polymorphisms both intra-and inter-species.Our previous studies revealed a Tourist-like MITE,Monkey King,associated with vernalization requirement of B.napus,however there are still few studies reveal MITE association with agricultural traits in B.napus.In the present study,80 polymorphic markers were developed from 55 MITEs,and used to evaluate genetic diversity in a panel of B.napus accessions consisting of 101 natural and 25 synthetic genotypes.Five agricultural traits,oil content,glucosinolate content,erucic acid content,weight of thousand seeds(WTS)and plant height,were investigated across 3-years field experiments,in addition,two traits,hypocotyl length and root length,were evaluated at the 4-leaf stage in the laboratory.Correlations between the MITE-based markers and seven traits were analyzed,finally,10 polymorphic markers produced by 6 pairs of MITE specific primers were revealed relatively high correlation with 5 traits.Two polymorphic markers were anchored with two candidate genes,BnaA02g13530D and BnaA08g20010D,respectively,which may contribute to glucosinolate content and WTS.This research may contribute to genetic improvement through utilization of MITE-induced polymorphisms in Brassica species. | Shutao Dai Jinna Hou Maomao Qin Ziju Dai Xiaojie Jin Shilei Zhao Yanhua Dong Yongxia Wang Zhengqing Wu Zhensheng Lei | 2021 | Oil Crop Science2021，6，1： | 0 |
| 19 | Dip-Pen Nanolithography(DPN): from Micro/Nano-patterns to Biosensing显示文摘Dip-pen nanolithography is an emerging and attractive surface modification technique that has the capacity to directly and controllably write micro/nano-array patterns on diverse substrates.The superior throughput,resolution,and registration enable DPN an outstanding candidate for biological detection from the molecular level to the cellular level.Herein,we overview the technological evolution of DPN in terms of its advanced derivatives and DPN-enabled versatile sensing patterns featuring multiple compositions and structures for biosensing.Benefitting from uniform,reproducible,and large-area array patterns,DPN-based biosensors have shown high sensitivity,excellent selectivity,and fast response in target analyte detection and specific cellular recognition.We anticipate that DPN-based technologies could offer great potential opportunities to fabricate multiplexed,programmable,and commercial array-based sensing biochips. | LI Haonan WANG Zhao HUO Fengwei WANG Shutao | 2021 | Chemical Research in Chinese Universities2021，37，4： | 0 |
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