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| 1 | Functionalized CVD monolayer graphene for label-free impedimetric biosensing显示文摘在大区域 graphene 生长的最近的进展在不同区域导致了许多应用。在现在的学习,化学蒸汽扔了(CVD ) 在玻璃底层上支持的单层 graphene 为电气化学的 biosensing 应用作为电极材料被检验。我们由在酸的水的答案在 situ 准备的 carboxyphenyl 重氮基盐的电气化学的减小为 CVD 单层 graphene 的共有原子价 functionalization 报导灵巧的策略。修改 carboxyphenyl 的 graphene 用拉曼光谱学, X 光检查光电子光谱学(XPS ) ,和原子力量被描绘显微镜学(AFM ) ,以及电气化学的阻抗光谱学(EIS ) 。我们也证明 graphene 表面上的 grafted carboxyphenyl 组的数字能被扫描为 electrografting 使用了的周期的 voltammetry (CV ) 的数字控制。我们进一步在 grafted 的激活以后在 graphene 表面上基于 ovalbumin 抗体的固定介绍 immunosensor 的制造和描述经由 EDC/NHS 化学的羧基的组。在使表面不能调动的抗体和 ovalbumin 之间的绑定然后用 Faradaic EIS 被监视在[Fe (CN )< 潜水艇 class= “ a-plus-plus ” > 6 ] 3/4 答案。费用转移抵抗的百分比变化(R < 潜水艇 class= “ a-plus-plus ” > 在绑定以后的 ct ) 为从 1.0 pg 的 ovalbumin 集中展出了线性依赖? | Shimaa Eissa Gaston Contreras Jimenez Farzaneh Mahvash Abdeladim Guermoune Chaker Tlili Thomas Szkopek Mohammed Zourob Mohamed Siaj | 2015 | Nano Research2015，8，5： | 3 |
| 2 | Dietary copper triggers onset of fulminant hepatitis in the Long-Evans cinnamon rat model显示文摘AIM:To investigate the impact of dietary copper given at different time points on the onset of fulminant hepatitis. METHODS:The Long-Evans cinnamon (LEC) rat model of Wilson's disease (WD) was used to study the impact of high dietary copper (hCu) on the induction of fulminant hepatitis at early or late time points of life. High Cu diet was started in rat pups or in adults (month 5) for three months. Animals that received reduced dietary copper (rCu) throughout their lifetime served as a control. Hepatitis-associated serum markers (alanine aminotransferase, aspartate transaminase, bilirubin) were analyzed in animal groups receiving hCu or rCu. Liver copper content and liver histology were revealed at sacrifice. A set of 5 marker genes previously found to be affected in injured liver and which are related to angiogenesis (Vegfa), fat metabolism (Srebf1), ex-tracellular matrix (Timp1), oxidative stress (Hmox1), and the cell cycle (Cdkn1a) were analyzed by real-time polymerase chain reaction. RESULTS:Regardless of the time point when hCu was started, LEC rats (35/36) developed fulminant hepatitis and died. Animals receiving rCu (36/36) remained healthy, did not develop hepatitis, and survived long term without symptoms of overt disease, although liver copper accumulated in adult animals (477 ± 75 μg/g). With regard to start of hCu, onset of fulminant hepatitis was significantly (P < 0.001) earlier in adults (35 ± 9 d) that showed pre-accumulation of liver copper as compared to the pup group (77 ± 15 d). Hepatitis-associated serum markers, liver copper and liver histology, as well as gene expression, were affected in LEC rats receiving hCu. However, except for early and rapid onset of hepatitis, biochemical and molecular markers were similar at the early and late time points of disease. CONCLUSION:Rapid onset of fulminant hepatitis in asymptomatic LEC rats with elevated liver copper suggests that there is a critical threshold of liver copper which is important to trigger the course of WD. | Ramsi Siaj Vanessa Sauer Sandra Stppeler Hans-Ullrich Spiegel Gabriele Khler Andree Zibert Hartmut HJ Schmidt | 2012 | World Journal of Gastroenterology2012，18，39： | 3 |
| 3 | Ionic liquids for CO2 capture-development and pro-gress 显示文摘 | HASIB-UR-RAHMAN M SIAJ M LARACHI F | 2010 | Chemical Engineering and Processing :Process Intensification2010，49，4： | 1 |
| 4 | Ionic liquids for CO2 capture-development and progress显示文摘 | Hasib-Ur-Rahman M Siaj M Larachi F | | 0，，04： | 1 |
| 5 | Ionic liquids for COz capture--Development and progress显示文摘 | Hasib-ur-Rahman M Siaj M Larachi F | 2010 | Chemical En- gineering and Processing: Process Intensification2010，49，4： | 1 |
| 6 | CO 2 capture in alkanolamineroom-temperature ionic liquid emulsions A viable approach with carbamate crystallization and curbed corrosion behavior显示文摘 | HASIB-UR-RAHMAN M SIAJ M LARACHI F A | 2012 | International Journal of Greenhouse Gas Control2012，6，： | 1 |
| 7 | Ionic liquids for CO2 capture--development and progress 显示文摘 | Hasib-ur-Rahman M Siaj M Larachi F | 2010 | Chemical Engineering and Processing2010，49，3： | 1 |
| 8 | Overexpressed ATP7B protects mesenchymal stem cells from toxic Copper显示文摘 | Sauer V Siaj R Todorov T | 2010 | Biochem Biophys Res Commun2010，395，3： | 1 |
| 9 | Electrochemical impedance immunosensor based on gold nanoparticles-protein G for the detection of cancer marker epidermal growth factor receptor in human plasma and brain tissue显示文摘 | Elshafey R Tavares AC Siaj M | | 0，，： | 1 |
| 10 | Ionic liquids for CO2 capturerevelopment and progress显示文摘 | Hasib-ur-Rahman M Siaj M Larachi F | 2010 | Chemical Engineering and Processing2010，49，： | 1 |
| 11 | Ionic liquids for CO 2 capture—Development and progress显示文摘 | M. Hasib-ur-Rahman M. Siaj F. Larachi | 2010 | Chemical Engineering & Processing: Process Intensification2010，，4： | 1 |
| 12 | Ionic liquids for CO 2 capture—Development and progress显示文摘 | M. Hasib-ur-Rahman M. Siaj F. Larachi | 2010 | Chemical Engineering & Processing: Process Intensification2010，，4： | 1 |
| 13 | Electrochemical impedance immunosensor based on gold nanoparticles - protein G for the detection of cancer marker epidermal growth factor receptor in human plasma and brain tissue 显示文摘 | Elshafey R Tavares A C Siaj M | 2013 | Biosensors & Bioelectronics2013，50，4： | 1 |
| 14 | Overexpressed ATP7B protects mesenchymal stem cells from toxic copper显示文摘 | Vanessa Sauer Ramsi Siaj Theodor Todorov Andree Zibert Hartmut H.-J. Schmidt | 2010 | Biochemical and Biophysical Research Communications2010，，3： | 1 |
| 15 | Ionic liquids for CO2capture--Development and progress显示文摘 | Hasib-ur-Rahmana M Siaj M Larachia F | 2010 | Chemical Engineeringand Processing2010，49，： | 1 |
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