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| 1 | Irritable bowel syndrome in children: Pathogenesis, diagnosis and evidence-based treatment显示文摘Irritable bowel syndrome(IBS)is the commonest cause of recurrent abdominal pain(RAP)in children in both more developed and developing parts of the world.It is defined by the RomeⅢcriteria for functional gastrointestinal disorders.It is characterized by abdominal pain that is improved by defecation and whose onset is associated with a change in stool form and or frequency and is not explained by structural or biochemical abnormalities.It is estimated that 10%-15%of older children and adolescents suffer from IBS.IBS can be considered to be a brain-gut disorder possibly due to complex interaction between environmental and hereditary factors.The diagnosis of IBS is made based on the RomeⅢcriteria together with ruling out organic causes of RAP in children such as inflammatory bowel disease and celiac disease.Once the diagnosis of IBS is made,it is important to explain to the parents(and children)that there is no serious underlying disease.This reassurance may be effective treatment in a large number of cases.Lifestyle modifications,stress management,dietary interventions and probiotics may be beneficial in some cases.Although there is limited evidence for efficacy of pharmacological therapies suchas antispasmodics and antidiarrheals;these have a role in severe cases.Biopsychosocial therapies have shown encouraging results in initial trials but are beset by limited availability.Further research is necessary to understand the pathophysiology and provide specific focused therapies. | Bhupinder Kaur Shu Siba Prosad Paul | 2014 | World Journal of Gastroenterology2014,20,20: | 8 |
| 2 | Environmental life cycle assessment of Indian coal-fired power plants显示文摘 | Udayan Singh Naushita Sharma Siba Sankar Mahapatra | 2016 | International Journal of Coal Science & Technology2016,3,2: | 5 |
| 3 | Gastric endoscopic submucosal dissection as a treatment for early neoplasia and for accurate staging of early cancers in a United Kingdom Caucasian population显示文摘AIM To investigate the efficacy of endoscopic submucosal dissection(ESD) at diagnosing and treating superficial neoplastic lesions of the stomach in a United Kingdom Caucasian population.METHODS Data of patients treated with or considered for ESD at a tertiary referral center in the United Kingdom were retrieved for a period of 2 years(May 2015 to June 2017) from the electronic patient records of the hospital. Only Caucasian patients were included. Primary outcomes were curative resection(CR) and were defined as ESD resections with clear horizontal and vertical margin and an absence of lympho-vascular invasion, poor differentiation and submucosal involvement on histological evaluation of the resected specimen. Secondary end-points were reversal of dysplasia at 12 mo endoscopic follow-up and/or at the latest follow up. Change in histological diagnosis pre and post ESD was also analysed.RESULTS Twenty-four patients were initially identified with intention to treat. 19 patients were eligible after mapping gastroscopy and ESD was attempted on a total of 25 ESD lesions, 4 of which failed and had to be aborted mid-procedure. Out of 21 ESD performed, en-bloc resection was achieved in 71.4% of cases. Resection was considered complete on endoscopy in 90.5% of cases compared to only 38.1% on histology. A total of 6 resections were considered curative(28%), 5 noncurative(24%) and 10 indefinite for CR or non-CR(24%). ESD changed the histological diagnosis in 66.6% of cases post ESD. Endoscopic follow-up in the 'indefinite' group and CR group showed that 50% and 80% of patients were clear of dysplasia at the latest follow-up respectively; 2 cases of recurrence were observed in the 'indefinite'group. Survival rate for the entire cohort was 91.7%.CONCLUSION This study provides early evidence for the efficacy of ESD as a therapeutic and diagnostic intervention in Caucasian populations and supports its application in the United Kingdom. | Aisha Sooltangos Matthew Davenport Stephen McGrath Jonathan Vickers Siba Senapati Kurshid Akhtar Regi George Yeng Ang | 2017 | World Journal of Gastrointestinal Endoscopy2017,9,12: | 3 |
| 4 | Case report of acute-on-chronic liver failure secondary to diffuse large B-cell lymphoma显示文摘Acute liver failure is a rare presentation of hematologic malignancy. Acute on chronic liver failure(ACLF) is a newly recognized clinical entity that describes acute hepatic decompensation in persons with preexisting liver disease. Diffuse large B-cell lymphoma(DLBCL) is an aggressive non-Hodgkin's lymphoma(NHL) with increasing incidence in older males, females and blacks. However, it has not yet been reported, to present with acute liver failure in patients with preexisting chronic liver disease due to human immunodeficiency virus(HIV)/hepatitis C virus(HCV) co-infection. We describe a case of ACLF as the presenting manifestation of DLBCL in an elderly black man with HIV/HCV coinfection and prior Hodgkin's disease in remission for three years. The rapidly fatal outcome of this disease is highlighted as is the distinction of ACLF from decompensated cirrhosis. Due to the increased prevalence of HIV/HCV co-infection in the African American 1945 to 1965 birth cohort and the fact that both are risk factors for chronic liver disease and NHL we postulate that the incidence of NHL presenting as ACLF may increase. | Yahuza Siba Kenechukwu Obiokoye Richard Ferstenberg James Robilotti Joan Culpepper-Morgan | 2014 | World Journal of Gastroenterology2014,20,44: | 3 |
| 5 | Chinese Grand Strategies in Central Asia:The Role of Shanghai Cooperation Organization and Belt and Road Initiative显示文摘Central Asia has long emerged as a hotspot for both the regional and extra-regional powers for two main reasons:its geopolitical location in the middle of Eurasia between Europe,South Asia,the Middle East,Russia and China,and their abundant and mostly unexplored natural resources.Sitting on huge untapped hydrocarbon potentials the Central Asian geographical entity in recent years has offered enormous opportunity and appeal for global countries and emerged as a grand chessboard for regional and extra-regional players.China is one such new pole in the new great game without which any geopolitical and geo-economic debate on Central Asia would be incomplete.With this prelude,this article attempts to analyse China's rise in Central Asia and its strategies to strengthen its position in the heartland region by discarding the much-hyped great game thesis and argues that China’s rise is unparallel and unmatched as testified by the recent Belt and Road Initiative of Beijing. | Ramakrushna Pradhan Siba Sankar Mohanty | 2021 | Fudan Journal of the Humanities and Social Sciences2021,14,2: | 3 |
| 6 | 适当收缩规模的城市:两个德国城市的案例(英文)显示文摘在当前城市发展领域的争论中,人们越来越认识到,欧洲的若干城市不得不面临长期萎缩的挑战。然而从国际范围看,在收缩和衰退发生时,规划范式、规划体系、规划战略和规划文化如何是否要有所改变,又该如何应对,都还不甚清晰。文章研究了收缩城市的规划如何转型,基于分析框架,提出了在面临收缩时如何识别规划模式和工具开始改变的起点。为此,文章简要介绍了两座收缩的德国城市:凯泽斯劳滕和茨维考。虽然凯泽斯劳滕和茨维考两个城市显示出不同萎缩城市规划模式的异同,但作者很清楚:由于他们的特殊路径和区位,这两个案例只是德国萎缩城市状况的一鳞半爪。文章着重于探讨如何处理衰退和收缩导致的城市规划变化以及不同的规划模式。文中案例展示出产业转型对德国制造业城镇的巨大影响,无论原东德还是西德,都导致失业、住房空置和人口流失的恶性循环。当谈到规划的转变,所有案例都展示出开发和再开发过程中,各种努力及其被接受的过程。被接受是一个过程,从最初的无视或否认,到关注和慢慢接受。增加人口扩大城市规模、维持现有设施和结构以阻止进一步衰退、重建和改造现有的基础设施,不同策略会导致不同的结果。大多数发展都试图挑战产生收缩的原因,设法扭转恶性循环。这些措施既可以作为扩张性规划策略的一部分,也可用于应对衰退策略,而这取决于具体做法。虽然替代性产业在各地各不相同,但它们的重要作用日益清晰:高科技、教育、医疗服务等如今都是新的经济支柱。事实上,在凯泽斯劳滕(茨维考则程度稍次),一所大学已被证明是发展的强大动力。 | Karina Pallagst René Fleschurz Siba Said | 2016 | 南方建筑2016,,2: | 2 |
| 7 | Geoepidemiology and environmental factors of psoria- sis and psoriatic arthritis 显示文摘 | Vinod C Siba PR | 2010 | Journal of Autoimmunity2010,34,3: | 1 |
| 8 | Inte grated learning particle swarm optimizer for global optimization显示文摘 | Sabat Samrat L Ali Layak Udgata Siba K | 2011 | Applied Soft Computing2011,11,1: | 1 |
| 9 | Invitro culture or triploid embryo culture grapes by ovulo embryo culture 显示文摘 | H Siba | 1995 | Vitis1995,7,1: | 1 |
| 10 | Role of IL-17 in Psoriasis and Psoriatic Arthritis显示文摘 | Siba P. Raychaudhuri | 2013 | Clinical Reviews in Allergy & Immunology2013,,: | 1 |
| 11 | Analysis of serum and cerebrospinal fluid cytokine levels in subacute scierosing panencephalitis in Papua New Guinea显示文摘 | Ichiyama T Siba P Suarkia D | 2006 | Cytokine2006,,: | 1 |
| 12 | Behavior of clayey soils on drying-wetting paths显示文摘 | JEAN-MARIE Fleureau SIBA Kheirbek-Saoud RIA Soemitro | 1993 | Canadian Geotehnical Journal1993,30,2: | 1 |
| 13 | Artificial bee colony algorithm for small signal model parameter extraction of MESFET显示文摘 | Samrat L. Sabat Siba K. Udgata Ajith Abraham | 2010 | Engineering Applications of Artificial Intelligence2010,,5: | 1 |
| 14 | Response of the estuarine cyanobacterium Lyngbya aestuarii to UV-B radiation显示文摘 | Jnanendra rath siba P Adhikary | 2007 | J Appl Phycol2007,19,: | 1 |
| 15 | Newcastle Disease Virus Exerts Oncolysis by both Intrinsic and Extrinsic Caspase-Dependent Pathways of Cell Death显示文摘 | Subbiah E Daniel R Siba K S | 2006 | Virology2006,80,15: | 1 |
| 16 | The large polymerase protein is associated with the virulence of Newcastle disease virus显示文摘 | Subrat N Siba K Samal | 2008 | Journal of Virology2008,8,16: | 1 |
| 17 | Role of intergenic sequences in Newcastle disease virus RNA transcription and pathogenesis显示文摘 | Yan Y Q Siba K Samal | 2008 | Journal of Virology2008,82,: | 1 |
| 18 | Nucleotide sequences of the trailer nucleocapsid protein gene and intergenic regions of Newcastle disease virus strain Beaudette C and completion of the entire genome sequence 显示文摘 | Krishnamurthy S Siba K S | 1998 | Journal of General Virology1998,79,: | 1 |
| 19 | Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis显示文摘 | Jennifer Chan B. R. Smoller Siba P. Raychauduri Wen-Yue Jiang Eugene M. Farber C. Chan | 1997 | Archives of Dermatological Research1997,,11: | 1 |
| 20 | Serum levels of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases 1 in subacute sclerosing panencephalitis显示文摘 | Ichiyama T Siba P Suarkia D | 2007 | J Neurol Sci2007,252,1: | 1 |