维普期刊资源整合服务平台（V6.5）

136篇 您的检索式：作者名="Silk M"

选中清除导出查看参考文献查看引证文献引用追踪共7页首页上一页第1页下一页末页 /7 跳转

	题名	作者	年代	出处	被引量
1	Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy.	Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz	2010	World Journal of Gastroenterology2010，16，8：	10
2	Use of a peptide rather than free amino acid nitrogen source in chemically defined 'elemental' diets显示文摘	SILK D B A FAIRCLOUGH P D CLARK M L	1980	Journal of Parenteral and Enteral Nutrition1980，4，：	1
3	Ubiquitin-proteasome pathway as a new targer for the prevention of restenosis显示文摘	Silke M Michael L Wina R	2002	Circulation2002，105，：	1
4	Application of high -speed countercurrent chromatography to the large-scale isolation of anthocyanins 显示文摘	M ichaels Silke H	2003	Biochemical Engineering Journal2003，14，：	1
5	Empirical Evaluation of Preservation Methods for Faecal DNA 显示文摘	FRANTZEN M A J SILK J B FERGUSON J W H	1998	Molecular Ecology1998，7，：	1
6	The propagation in metal tub ing of ultrasonic wave modes equivalenl to Lamb waves 显示文摘	Silk M G Ikainton K P	1979	Uhrasonlcs1979，17，：	1
7	Perfluorooctanoic acid and perfluorooetane suffonate in the sediment of the Roter Main River, Bayreuth, Germany 显示文摘	BECKER A M SILKE G HARTMUT F	2008	Environmental Pollution2008，156，3：	1
8	Jejunal absorption of an amino acid mixture simulating casein and an enzymic hydrolysate of casein prepared for oral administration to normal adults 显示文摘	Silk D B Clark M L Marrs T C	1975	J British Nutr1975，33，1：	1
9	The influence of fuel structure on combustion as demonstrated by the isomers of heptane: A rapid compression machine study显示文摘	Silke Emma J Curran Henry J Simmie John M	2005	Proceedings of the Combustion Institute2005，30，：	1
10	The propagation in metal tubing of ultrasonic wave modes equivalent to Lamb waves 显示文摘	Silk M G Bainton K F	1979	Ultrasonics1979，17，1：	1
11	Extent,pattern and factors associated with late embryonic loss in dairy cows显示文摘	Silke V Diskin M G Kenny D A	2002	Animal Reproduction Science2002，71，：	1
12	Right parietal dysfunction in children with attention deficit hyperactivity disorder,combined type:a functional MRI study显示文摘	Vance A Silk TJ Casey M	2007	Mol Psychiatry2007，12，83：	1
13	The use of diffraction-based time-of-flight measurements to locate and size defects显示文摘	Silk M G	1984	The British Journal of NDT1984，26，4：	1
14	Effect of water stress on cor- tical cell division rates within the apical meristem of primary roots of maize显示文摘	Sacks M M Silk W K Burman P	1997	Plant Physiology1997，114，2：	1
15	A lead-gill binding model to predict acute lead toxicity to rainbow trout ( Oncorhynchus mykiss ) 显示文摘	Macdonald A Silk L Schwartz M	2002	Comp Biochem Physiol C2002，133，12：	1
16	The propagation in metal tubing of ultrasonce wave modes equivalent to lamb waves显示文摘	Silk M G Bainton K F	1979	Ultrasonics1979，17，1：	1
17	Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulmlnant liver injury 显示文摘	Jutta L Silke M JUrgen B	2008	Gastroenterology2008，134，4：	1
18	The Propagation in Metal Tubing of Ultrasonic Wave Modes Equivalent to Lamb Waves显示文摘	SILK M G BAINTON K F	1979	Ultrasonics1979，17，1：	1
19	Radiofrequency ablation of tl lung carcinoma: comparison of outcomes for first primary, metachro- nous, and synchronous lung tumors显示文摘	Ridge CA Silk M Petre EN	2014	J Vase Interv Radiol2014，25，7：	1
20	Screening of commercial sorbents for the removal of reactive dyes显示文摘	Silke K Kornmuller A Jekel M	2001	Dyes Pigments2001，51，23：	1

返回顶部每页显示：

共7页首页上一页第1页下一页末页 /7 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示