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| 1 | Helicobacter pylori infection: Beyond gastric manifestations显示文摘Helicobacter pylori(H.pylori)is a bacterium that infects more than a half of world’s population.Although it is mainly related to the development of gastroduodenal diseases,several studies have shown that such infection may also influence the development and severity of various extragastric diseases.According to the current evidence,whereas this bacterium is a risk factor for some of these manifestations,it might play a protective role in other pathological conditions.In that context,when considered the gastrointestinal tract,H.pylori positivity have been related to Inflammatory Bowel Disease,Gastroesophageal Reflux Disease,Non-Alcoholic Fatty Liver Disease,Hepatic Carcinoma,Cholelithiasis,and Cholecystitis.Moreover,lower serum levels of iron and vitamin B12 have been found in patients with H.pylori infection,leading to the emergence of anemias in a portion of them.With regards to neurological manifestations,a growing number of studies have associated that bacterium with multiple sclerosis,Alzheimer’s disease,Parkinson’s disease,and Guillain-Barrésyndrome.Interestingly,the risk of developing cardiovascular disorders,such as atherosclerosis,is also influenced by the infection.Besides that,the H.pylori-associated inflammation may also lead to increased insulin resistance,leading to a higher risk of diabetes mellitus among infected individuals.Finally,the occurrence of dermatological and ophthalmic disorders have also been related to that microorganism.In this sense,this minireview aims to gather the main studies associating H.pylori infection with extragastric conditions,and also to explore the main mechanisms that may explain the role of H.pylori in those diseases. | Maria Luisa Cordeiro Santos Breno Bittencourt de Brito Filipe Antonio França da Silva Mariana Miranda Sampaio Hanna Santos Marques Natalia Oliveira e Silva Dulciene Maria de Magalhaes Queiroz Fabricio Freire de Melo | 2020 | World Journal of Gastroenterology2020，26，28： | 34 |
| 2 | SMARCA4表达缺失是诊断卵巢高钙血症型小细胞癌既敏感又特异性的指标显示文摘卵巢高钙血症型小细胞癌是一种非常罕见的卵巢肿瘤,好发于年轻女性,预后差。临床因其罕见并具有相对非特异性的组织学特征,仅依靠组织学诊断极具有挑战性。组织学上卵巢高钙血症型小细胞癌具有从经典的、最初描述的小细胞形态到含丰富嗜酸性胞质的大细胞形态,因此需与多种肿瘤实体进行鉴别诊断。 | Conlon N Silva A Guerra E 魏建国(摘译) 许春伟(审校) | 2016 | 临床与实验病理学杂志2016，32，7： | 15 |
| 3 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 4 | Non-pharmacological management of pediatric functional abdominal pain disorders:Current evidence and future perspectives显示文摘Functional abdominal pain disorders(FAPDs) are an important and prevalent cause of functional gastrointestinal disorders among children, encompassing the diagnoses of functional dyspepsia, irritable bowel syndrome, abdominal migraine, and the one not previously present in Rome Ⅲ, functional abdominal pain not otherwise specified. In the absence of sufficiently effective and safe pharmacological treatments for this public problem, non-pharmacological therapies emerge as a viable means of treating these patients, avoiding not only possible side effects, but also unnecessary prescription, since many of the pharmacological treatments prescribed do not have good efficacy when compared to placebo. Thus, the present study provides a review of current and relevant evidence on non-pharmacological management of FAPDs, covering the most commonly indicated treatments, from cognitive behavioral therapy to meditation, acupuncture, yoga, massage, spinal manipulation, moxibustion, and physical activities. In addition, this article also analyzes the quality of publications in the area, assessing whether it is possible to state if non-pharmacological therapies are viable, safe, and sufficiently well-based for an appropriate and effective prescription of these treatments. Finally, it is possible to observe an increase not only in the number of publications on the non-pharmacological treatments for FAPDs in recent years, but also an increase in the quality of these publications. Finally, the sample selection of satisfactory age groups in these studies enables the formulation of specific guidelines for this age group, thus avoiding the need for adaptation of prescriptions initially made for adults, but for children use. | Maria Luísa Cordeiro Santos Ronaldo Teixeira da Silva Júnior Breno Bittencourt de Brito Filipe Antônio França da Silva Hanna Santos Marques Vinícius Lima de SouzaGonçalves Talita Costa dos Santos Carolina Ladeia Cirne Natália Oliveira e Silva Márcio Vasconcelos Oliveira Fabrício Freire de Melo | 2022 | World Journal of Clinical Pediatrics2022，11，2： | 2 |
| 5 | Influence of age in estimating maximal oxygen uptake显示文摘ObjectiveTo 在最大的氧举起的估计( EE )的错误上估计年龄的影响( VO 2最大)用性别和在自从估计,测试的周期测力计锻练特定方程的人口, VO 2最大与实质的 EE 被联系,经常超过20%, 18~91 年,可能,由于机械 efficiency.Methods1850 的内在的可变性,成年人(68%人)经历了最大的周期测力计测试的心肺的锻练。心和肺的健康(CRF ) 相对性别和年龄被估计[更年轻(18 ~ 35 年) ,中年(36 ~ 60 年) 并且更旧(>60 年)] 。VO 2 最大[mL·(kg· min )−1] 被对煤气的交换的评价直接测量并且估计了使用性别和人口特定方程。VO 2 最大和相关 EE 在三年龄特定、性特定的 groups.ResultsDirectly 测量的 VO 2 男人和女人的最大是 29.5 ±10.5 mL·(kg· min )−1 和 24.2 ±9.0 mL·(kg· min )−1(P <0.01 ) 。EE [mL·(kg· min ) 为男人和女人的 −1] 和百分比错误(% E ) 有类似的价值, 0.5 ±3.2 和 0.4 ±2.9 mL·(kg· min )−1, 和 − 0.8 ±13.1% 并且 − 1.7 ±15.4%(P >0.05 ) 分别地。分别地,为每个年龄组的 EE 和 % E 为男人:更年轻的 = 1.9 ±4.1 mL·(kg· min )−1 和 3.8 ±10.5% ,中年的 = 0.6 ±3.1 mL·(kg· min )−1 和 0.4 ±10.3% ,更旧的 =− 0.2 ±2.7 mL·(kg· min )−1 和 − 4.2 ±16.6%(P <0.01 ) ;并且为女人:更年轻的 = 1.2 ±3.1 mL·(kg· min )−1 和 2.7 ±10.0% ,中年的 = 0.7 ±2.8 mL·(kg· min )−1 和 0.5 ±11.1% ,更旧的 =-0.8 ±2.3 mL·(kg· min )−1 和 − 9.5 ±22.4%(P <0.01 ).ConclusionVO 2 最大在更年轻的年龄组被低估并且在老年组被过高估计。年龄显著地影响 VO 2 在男人和女人的最大并且当 CRF 用人口被估计时,应该被认为特定方程,而非直接测量了。 | Christina G de Souza Silva Barry A Franklin Daniel E Forman Claudio Gil S Araujo | 2016 | Journal of Geriatric Cardiology2016，13，2： | 2 |
| 6 | Sulphate removal from industrial wastewater using a packed-bed anaerobic reactor显示文摘 | Silva A J Varesche M B Foresti E | 2002 | Process Biochem2002，37，9： | 1 |
| 7 | Decreased sperm motility in rats orally exposed to single or mixed pesticides 显示文摘 | Perobelli J E Martinez M F da Silva Franchi C A | 2010 | Journal of Toxicology and Environment Health A2010，73，1314： | 1 |
| 8 | Estrogens and gcnomic instability in human breast cancer cells-involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals显示文摘 | KABIL A SILVA E KORTENKAMP A | 2008 | Carcinogenesis2008，29，10： | 1 |
| 9 | A novel muta-tion in the growth and differentiation factor 9 (GDF9)gene is associated, in homozygosis, with increased ovula-tion rate in Santa Ines sheep 显示文摘 | Melo E O Silva B D M Castro E A | 2008 | Biology of Reproduction2008，78，141： | 1 |
| 10 | Coastal zone management:tools for establishing a set of indicators to assess beach carrying capacity(Coata del Sol-Spain)显示文摘 | Jurado E Dantas A G Carlos Pereira da Silva | 2009 | Journal of Coastal Research2009，，56： | 1 |
| 11 | Fault detection of open-switch damage in voltage fed PWM motor drive systems 显示文摘 | Ribeiro R L A Jacobina C B Silva E R C D | 2003 | IEEE Transactions on Power Electronics2003，18，2： | 1 |
| 12 | The effect of colchicine on liver function tests and hepatic fibrosis in patients with chronic active hepatitis:a study of 3 cases(author's transl)显示文摘 | Leandro P Ade O e Silva A BrandSo J F Saldanha L B Pontes J F | 2013 | Arquivos de Gastroenterologia2013，15，3： | 1 |
| 13 | Adsorption equilibria and kinetics for propylene and propane over 13X and 4A zeolites pellets显示文摘 | RODRIGUES A E | 1999 | Ind Eng Chem Res1999，38，5： | 1 |
| 14 | Pulsed-field gel electrophoresis(PFGE) analysis of Listeria monocytogenes isolates from different sources and geographical origins and representative of the twelve serovars 显示文摘 | Neves E Lourenco A Silva A C | 2008 | Syst Appl Microbiol2008，31，5： | 1 |
| 15 | Effects of environmental factors, age and genotype on sperm production and semen quality in Bos indicus and Bos taurus AI bulls in Brazil显示文摘 | Brito L F Silva A E Rodriques L H | 2002 | Animal Reproduction Science2002，70，34： | 1 |
| 16 | Effect of key operating parameters on phenols degrada-tion during H2O2-assisted TiO2 photocatalytic treat-ment of simulated and actual olive mill wastewaters 显示文摘 | Silva A M T Nouli E Xekoukoulotakis N P | 2007 | Appl Catal B: Environ2007，73，12： | 1 |
| 17 | Inhibitory action of aqueous coffee ground extracts on the corrosion of carbon steel in HC1 solution 显示文摘 | TORRESS V V AMADO R S de sAC F FERNANDEZ T L da SILVA RIEHI C A TORRES A G D'ELIA E | 2011 | Corrosion Science2011，53，： | 1 |
| 18 | Comparative effects of salinity and water stress on photosynthesis, water relations and growth of Jatropha curcas plant 显示文摘 | SILVA E N RIBEIRO R V FERREIRA-SILVA S L VIEGAS R A SILVEIRA J A G | 2010 | Journal of Arid Environment2010，74，10： | 1 |
| 19 | Selec- tive precipitation/UV production of magnetite particles obtained from the iron recovered from acid mine drain- age 显示文摘 | Silva R A Castro C D Viganico E M | 2012 | MinerEng2012，，： | 1 |
| 20 | A simple solid injection device for the analyses of Bulbophyllum (Orchidaceae) volatiles 显示文摘 | da Silva U F Borba E L Semir J Marsaioli A J | 1999 | Phytochemistry1999，50，： | 1 |
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