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54篇 您的检索式:作者名="Silva GV"
    题名 作者 年代 出处 被引量
1Value of a newly sequenced bacterial genome显示文摘Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size laboratories, culminating in a tidal wave of genomic information. The quantity of sequenced bacterial genomes has not only brought excitement to the field of genomics but also heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting in an exponential increase in draft(partial data) genome deposits in public databases. If no further interests are expressed for a particular bacterial genome, it is more likely that the sequencing of its genome will be limited to a draft stage, and the painstaking tasks of completing the sequencing of its genome and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the 'scientific value' of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information.Eudes GV Barbosa Flavia F Aburjaile Rommel TJ Ramos Adriana R Carneiro Yves Le Loir Jan Baumbach Anderson Miyoshi Artur Silva Vasco Azevedo 2014World Journal of Biological Chemistry2014,5,2:7
2A phase II Dose-Escalation study of allogeneic mesenchymal precursor cells in patients with ischemic or nonischemic heart failure 显示文摘Perin EC Borow KM Silva GV 2015Circ Res2015,117,6:1
3A randomized study of transendocardial injection of autologous bone marrow mono- nuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF) 显示文摘Perin EC Silva GV Henry TD 2011Am Heart J2011,161,6:1
4Stress urinary incontinence in women belonging to the Family Health Program of Dourados/MS 显示文摘Gomes GV Silva GD 2010Rev Assoc Med Bras2010,56,6:1
5A randomized study of transendocardial injection of autologous bone marrow mononucle- ar cells and cell functionanalysis in ischemic heart failure ( FO- CUS-HF) 显示文摘Perin EC Silva GV Henry TD 2011Am Heart J2011,161,6:1
6Assessing intermediate coronary le- sions : angiographic prediction of lesion severity on intravascular ultrasound 显示文摘Femandes MR Silva GV Caixeta A 2007J Invasive Cardiol2007,19,:1
7Comparative healing response after sirolimus-and paelitaxel-eluting stent implantation in a pig model of restenosis 显示文摘Silva GV Fernandes MR Madonna R 2009Catheter Cardiovasc luterv2009,73,6:1
8Studies on the encapsulation of diclofenac in small unilamellar liposomes of soya phosphatidylcholine显示文摘Lopes LB Scarpa MV Silva GV 2004Colloids Surf B Biointerfaces2004,39,4:1
9Comparative healing response after sirolimus- and paelitaxel-eluting stent implantation in a pig model of restenosis 显示文摘Silva GV Fernandes MR Madonna R 2009Catheter Cardiovase luterv2009,73,6:1
10Cryoplasty for peripheral artery disease inan unselected patient population in a tertiary center显示文摘Silva GV Femandes MR 2011Tex HeartInst J2011,38,2:1
11Cryoplasty for peripheral artery disease in an unselected patient population in a tertiary center显示文摘Silva GV Femandes MR 2011Tex Heart Inst J2011,38,2:1
12Mesenchymal Stem Cells Differentiateintoan into an Endothelial Phenotype,enhance Vascular Density,and Improve Heart Functionina Canine Chronic Ischemia Model显示文摘Silva GV Litovsky S Assad JA 2005Circulation2005,111,2:1
13Catheter-based transendocardial delivery of autologous bone-marrow-derived mononuclear cells in patients listed for heart transplantation显示文摘Silva GV Perin EC Dohmann HF 2004Tex Heart Inst J2004,31,3:1
14Cryoplasty for peripheral artery disease in an unselected patient population in a tertiary center显示文摘Silva GV Fernandes MR 2011Tex Heart Inst J2011,38,2:1
15Comparison of intracoronary andtransendocardial delivery of allogeneic mesenchymal cells in a caninemodel of acute myocardial infarction显示文摘Perin EC Silva GV Assad JA 2008J Mol Cell Cardiol2008,44,3:1
16Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction 显示文摘Perin EC Silva GV Assad JA 2008J Mol Cell Cardiol2008,44,3:1
17Effects of carvedilol therapy on QT - interval dispersion in congestive heart failure: Is there a difference in the elderly? 显示文摘Rocha RM Silva GV Perin EC 2003Tex Heart Inst J2003,30,3:1
18Diabetic and nondi- abetic patients respond differently to transendocardial injection of bone marrow mononuclear cells:findings from prospective clinical trials in 'no-option' patients显示文摘Jimenez-Quevedo P Silva GV Sanz-Ruiz R 2008Rev Esp Cardiol2008,61,6:1
19Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain显示文摘Meirelles GV Silva JC Mendon Yuri de A 2011BMC Struct Biol2011,11,12:1
20Effects of carvedilol therapy on QT-interval dispersion in congestive heart failure:Is there a difference in the elderly显示文摘Rocha RM Silva GV Perin EC 2003Tex Heart Inst J2003,30,3:1
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