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164篇 您的检索式:作者名="Silva U"
    题名 作者 年代 出处 被引量
1Differences in viral kinetics between genotypes 1 and 3 of hepatitis C virus and between cirrhotic and non-cirrhotic patients during antiviral therapy显示文摘AIM: To evaluate the impact of hepatitis C virus (HCV) infection with genotype 1 or 3 and the presence or absence of liver cirrhosis (LC) in the early viral kinetics response to treatment. METHODS: Naive patients (n = 46) treated with interferon-α (IFN-α) and ribavirin and followed up with frequent early HCV-RNA determinations were analysed. Patients were infected with genotype 1 (n = 28, 7 with LC) or 3 (n = 18, 5 with LC). RESULTS: The fi rst phase decline was larger in geno- type 3 patients than in genotype 1 patients (1.72 vs 0.95 log IU/mL, P < 0.001). The second phase slope decline was also larger in genotype 3 patients than in genotype 1 patients (0.87 vs 0.15 log/wk, P < 0.001). Differences were found in both cirrhotic and non-cirrhotic patients. Genotype 1 cirrhotic patients had a slower 2nd phase slope than non-cirrhotic patients (0.06 vs 0.18 log/wk, P < 0.02). None of genotype 1 cirrhotic patients had a 1st phase decline larger than 1 log (non-cirrhotic patients: 55%, P < 0.02). A similar trend toward a slower 2nd phase slope was observed in genotype 3 cirrhotic pa- tients but the 1st phase slope decline was not different. Sustained viral response was higher in genotype 3 pa- tients than in genotype 1 patients (72% vs 14%, P < 0.001) and in genotype 1 non-cirrhotic patients than in genotype 1 cirrhotic patients (19% vs 0%). A secondphase decline slower than 0.3 log/wk was predictive of non-response in all groups. CONCLUSION: Genotype 3 has faster early viral decline than genotype 1. Cirrhosis correlates with a slower 2nd phase decline and possibly with a lower 1st phase slope decline in genotype 1 patients.José Eymard Medeiros-Filho Isabel Maria Vicente Guedes de Carvalho Mello Joo Renato Rebello Pinho Avidan U Neumann Fernanda de Mello Malta Luiz Caetano da Silva Flair José Carrilho 2006World Journal of Gastroenterology2006,12,45:3
2Bone defects following curettage do not necessarily need augmentation显示文摘Him M de Silva U Sidharthan S 2009Acta Orthop2009,80,1:1
3A simple solid injection device for the analyses of Bulbophyllum (Orchidaceae) volatiles 显示文摘da Silva U F Borba E L Semir J Marsaioli A J 1999Phytochemistry1999,50,:1
4Risk factors for the increasing cesarean section rate in Southeast Brazil: a comparison of two birth cohorts 1978-1979 and 1994显示文摘GOMES U A SILVA A A BETTIOL H 1999J Epidemical1999,28,4:1
5Amazon drought and its implications for forest flammability and tree growth : a basin-wide analysis 显示文摘NEPSTAD D LEFEBVRE P SILVA U L D 2004Global Change Biology2004,10,:1
6The invasion of Pteridium aquilinum and the impoverishment of the seed bank in fire prone areas of Brazilian Atlantic Forest显示文摘DE SILVA(U) MATOS D 2006Biodiversity and Conservation2006,15,:1
7Surface cellulose modification with 2-aminomethylpyridine for copper, cobalt, nickel and zinc removal from aqueous solution显示文摘Silva Filho E C J u nior S Sousa L 2013Materials Research2013,16,1:1
8Cone-beam computed to- mography for routine orthodontic treatment planning: A radiation dose evaluation显示文摘Silva MA Wolf U Heinicke F 2008Am J Orthod Dentofacial Orthop2008,133,5:1
9Thermochemistry of interaction between ceUulose modified with 2-aminomethylpyridine and divalent cations显示文摘Silva Filho E C J u nior L S S Santos M R M C 2013Journal of thermal analysis and calorimetry2013,114,1:1
10Application of laser photoacoustic spectroscopy for the analysis of gas samples emitted by diesel engines显示文摘Chramm D U Sthel M S Silva M G etal 2003Infrared Physics & Technology2003,44,4:1
11An alternative method of arterial reconstruction in pediatric living donor liver transplantation with the recipient right graftroepiploic artery显示文摘TANNURI U AKSOUD-FILBO J G M SILVA M M 2006Pediatric Transplant2006,10,1:1
12Li- popolysaccharide is in close proximity to each of the proteins in its membrane recept or complex transfer from CD14 to TLR4 and MD - 2显示文摘DA SILVA CORREIA J SOLDAU K CHRISTEN U 2001J Biol Chem2001,276,21:1
13Catalytic activity and stability of a chromium containing silicate in liquid phase cyclohex- ane oxidation 显示文摘da Cruz R S e Silva J M S Aruold U I 2001Journal of Molecular Catalysis A : Chemical2001,171,1:1
14Cell adhesion mole-eule Ll modu-lates nerve-growth-factor-induced CGR-P-IR fibersproutirtg 显示文摘Chaudhry N Silva U Smith GM 2006Exp Neural2006,1,:1
15Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex显示文摘Da Silva Correia J Soldau K Christen U 0,,24:1
16Wideband low-distortion delta-sigma ADC topology显示文摘Silva J Moon U Steensgaard J 0,,12:1
17Prevalence of Acanthosis Nigricans in an urban population in Sfi Lanka and its utility to detect metabolic syndrome显示文摘Dassanayake AS Kasturiratne A Niriella MA Kalubovila U Rajindrajith S de Silva AP 2011BMC Res Notes2011,4,1:1
18Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans显示文摘Garlet TP Coelho U Silva JS 2007Eur J Oral Sci2007,115,5:1
19Wideband low-distortion delta-sigma ADC topology 显示文摘SILVA J MOON U STEENSGAARD J 2001ElecLett2001,37,12:1
20Lipopolysaccharide is inclose proximity to each of the proteins in its membrane receptor complex transfer from CD14 to TLR4 and MD-2 显示文摘da Silva Correia J Soldau K Christen U 2001J Biol Chem2001,276,21:1
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