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| 1 | Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy显示文摘我们与优先的主要雄激素剥夺治疗(ADT ) 在变形前列腺癌症在前进木头(PSAVAP ) 以后调查了前列腺特定的抗原天底(TTPN ) 和前列腺特定的抗原速度的对数的时间的协会。从 2000 ~ 2009 与主要 ADT 对待的所有变形前列腺癌症病人被考察。开发了疾病前进的病人在随后的分析被包括。病人们根据他们的 TTPN 被分成三个组:< 的 TTPN; 3 个月, 3-17 月,和 > 17 个月。我们用 Mann-Whitney U-test 和 Kruskal-Wallis 测试比较了在不同 TTPN 组之间的木头(PSAVAP ) 。木头(PSAVAP ) 上的进一步多重的线性回归分析被执行为使因素惊讶的另外的潜力调整。在与主要 ADT 被对待的 419 个病人之中, 306 个病人与 28 个月的中部的后续开发了疾病前进。更长的 TTPN 与更低的木头(PSAVAP ) 被联系(P = 0.008 ) 在所有亚群分析以内(< 的 TTPN; 3 对 3-17 月, P = 0.020;3-17 对 > 的 TTPN; 17 个月, P = 0.009;并且 < 的 TTPN; 3 对 > 17 个月, P = 0.001 ) 。在多重线性回归分析之上,基线 PSA (回归系数 0.001 , P = 0.045 ), PSA 天底(回归系数 0.002 , P = 0.040 ),并且 TTPN (回归系数 − ; 0.030 , P = 0.001 )是显著地与木头( PSAVAP )被联系的三个因素。在结论,更长的 TTPN 在跟随主要 ADT 的变形前列腺癌症病人与更低的木头(PSAVAP ) 被联系。在 3 个月和 17 个月的 TTPN cut-offs 看起来在预言木头(PSAVAP ) 有预示的意义。TTPN 可以在与疾病前进在病人决定治疗策略用作好预示的指示物。 | Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 6 |
| 2 | Outcome analysis of management of liver trauma: A 10-year experience at a trauma center显示文摘AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality. | Wong Hoi She Tan To Cheung Wing Chiu Dai Simon HY Tsang Albert CY Chan Daniel KH Tong Gilberto KK Leung Chung Mau Lo | 2016 | World Journal of Hepatology2016，8，15： | 3 |
| 3 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，3： | 1 |
| 4 | Maternal hy- perinsulinism and glycaemic status in the first trimester of pregnancy arc associated with lhe development of preg- nancy induced hypertension and gestational diabetes 显示文摘 | Simon KK Catherine P Michael PP | 2013 | Eur J Endocrinol2013，168，3： | 1 |
| 5 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，96，： | 1 |
| 6 | Estrogen in intrahepatic cholestasis of pregnancy 显示文摘 | Lesle KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，： | 1 |
| 7 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Reznikov L Simon FR | 2000 | Gynecol2000，95，： | 1 |
| 8 | Estrogensin in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，3： | 1 |
| 9 | Xenophagy in Helicobacter pylori ‐ and Epstein–Barr virus‐induced gastric cancer显示文摘 | Lin Zhang Joseph JY Sung Jun Yu Siew C Ng Sunny H Wong Chi H Cho Simon SM Ng Francis KL Chan William KK Wu | 2014 | Pathol2014，，2： | 1 |
| 10 | Estrogens in intrahepaticcholestasis of pregnancy显示文摘 | Leslie KK Reznikow L Simon FR | 2000 | Obstet Gynecol2000，95，6： | 1 |
| 11 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | | 0，，： | 1 |
| 12 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，3： | 1 |
| 13 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikow L Simon FR | 2000 | Obstet Gynecol2000，95，6： | 1 |
| 14 | Advanced oocyte cryopreservation will not undermine the practice of ethical egg sharing显示文摘 | Ahuja KK Simons EG | 2006 | Reproductive Biomedicine Online2006，12，3： | 1 |
| 15 | Estrogens inintrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，3： | 1 |
| 16 | Estrogens in intrahepatic Cholestasis of pregnancy显示文摘 | Leslie kk Reznikov L Simon FR | 2000 | Obstetrics Gynecology2000，95，3： | 1 |
| 17 | Estrogem in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol12000，95，3： | 1 |
| 18 | Estrgens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | J Obstet Gynecol2000，95，3： | 1 |
| 19 | Estrogens in Intrahepatic Cholestasis of Pregnancy ( ICP ) 显示文摘 | Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，： | 1 |
| 20 | Estrogens in intrahepatic cholestasis of pregnancy显示文摘 | Leslie KK Reznikov L Simon FR | 2000 | Obstet Gynecol2000，95，3： | 1 |
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