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| 1 | Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits显示文摘 | Heise N De Silva NS Silva K Carette A Simonetti G | 2014 | J Exp Med2014，211，10： | 1 |
| 2 | Assessing the biogenicity and syngenicity of candidate bioalteration textures in pillow lavas of the~2.52 Ga Wutai greenstone terrane of China显示文摘住在 sub-seafloor 熔岩的微生物能够蚀刻暴烈的玻璃并且创造微米大小的隧道和坑。这些 bioalteration 踪迹的矿化作用保证这些质地熬过主人玻璃的变丑和转变到变形矿物质。如此的 bioalteration 质地的石块记录从在原处海洋的外壳在暴烈的玻璃以外远延长从 ophiolites 和前寒武纪的绿岩带包括元暴烈的玻璃。薄节从 N 的 Wutai 组从 2.52 Ga tholeiitic 枕头熔岩这里报导了的 petrographic 的调查。中国成立细丝状微质地。激光拉曼光谱学证实这些质地被 titanite 使矿物化。而且, Wutai 微质地在到从太古代的 greenschist 外形枕头熔岩的 bioalteration 质地的尺寸,形态学和分发是可比较的。在原处,诱导地由激光脱离多收集者 titanite 标明日期的 U-Pb 联合了团 spectrometry (LA-MC-ICP-MS ) 给 1.81 敢 ? 汢獥敳 ? 楷桴的年龄的血浆吗? | McLOUGHLIN N FLIEGEL DJ FURNES H STAUDIGEL H SIMONETTI A ZHAO GuoChun ROBINSON P T | 2010 | Chinese Science Bulletin2010，55，2： | 1 |
| 3 | Polyphenol content and total antioxidant activity of vini novelli(young red wines)显示文摘 | Pellegrini N Simonetti P Gardana C | 2000 | Journal of Agricultural and Food Chemistry2000，48，3： | 1 |
| 4 | Tetracycline in combination with sodium dioctyl sulfosuccinate show increased antimicrobial activity in resistant microorganism显示文摘 | Simonetti G Simonetti N Villa A | 2004 | J Chemother2004，16，： | 1 |
| 5 | Renal sympathetic nerve ablation for the treatment of difficult-to-control or refractory hypertension in a haemodialysis patient显示文摘 | Di Daniele N De Francesco M Violo L Spinelli A Simonetti G | 2012 | Nephrol Dial Transplant2012，27，： | 1 |
| 6 | Combining time of flight and diffraction tomography for high resolution breast imaging: Initial in-vivo results (1) 显示文摘 | HUTHWAITE P SIMONETTI F DURIC N | 2012 | The Journal of the Acoustical Society of America2012，132，3： | 1 |
| 7 | The diverse roles of IRF4in late germinal center B-cell differentiation显示文摘 | De Silva NS Simonetti G Heise N | 2012 | Immunol Rev2012，247，1： | 1 |
| 8 | In vitro antimicrobial activity of econazole and miconazole sulfoslicylate显示文摘 | D'Auria F D Simonetti N | 1990 | Drugs Exp Clin Res1990，16，： | 1 |
| 9 | Temporal trends of pollution Pb and other metals in east-central Baffin Island inferred from lake sediment geochemistry显示文摘 | Michelutti N Simonetti A Briner J P | 2009 | Science of the Total Environment2009，407，56： | 1 |
| 10 | In situ petrographic thin section IJ-Pb dating o( zircon, monazite, and titanite using laser ablation MC-ICP-MS 显示文摘 | Simonetti A Heaman L M Chaeko T Banerjee N R | 2006 | jnternational Journal of Mass Spectrometry2006，253，： | 1 |
| 11 | Soil macro-and microstructure as affected by different tillage systems and their effects on maize root growth显示文摘 | Dal Ferro N Sartori L Simonetti G | 2014 | Soil and Tillage Research2014，140，： | 1 |
| 12 | 中国五台绿岩带2.52Ga枕状熔岩中候选生物改造结构的生物成因性和同生性评估显示文摘栖居于海底熔岩基底中的微生物能够侵蚀火山玻璃,形成微米级的孔洞和钻穴.这些生物改造的遗迹被矿化后,即使保存它们的火山玻璃经历了变形和改造成为变质矿物后,矿化的结构也能够保存下来.这些生物改造结构的化石记录所赋存的岩性远远超出了原位洋壳火山玻璃的范围.它们可见于蛇绿岩和前寒武纪绿岩带的变火山玻璃中.本文报道了中国五台山25.2亿年拉斑质枕状熔岩薄片中发现的丝状体型生物显微结构.而且,五台绿岩中发现的微结构在大小、形态和分布上都可以与其他产在太古宙绿片岩相枕状熔岩中的生物蚀变结构相对比.榍石LA-MC-ICP-MSU-Pb原位定年分析给出的年龄是(1.81±0.12)Ga(2σ,n=22,206Pb/238U加权平均).该年龄提供了这些生物蚀变结构矿化的最小年龄,并与区域变质事件年龄相当.这个年龄也代表这些生物蚀变时间的最小年龄估计,从而支持晚太古宙海底生物圈的存在. | McLOUGHLIN N FLIEGEL D J FURNES H STAUDIGEL H SIMONETTI A 赵国春 ROBINSON P T | 2010 | 科学通报2010，55，12： | 0 |
| 13 | Consensus molecular subtypes of colorectal cancer in clinical practice:A translational approach显示文摘The identification of several genetic mutations in colorectal cancer(CRC)has allowed a better comprehension of the prognosis and response to different antineoplastic treatments.Recently,through a systematic process,consensus molecular subtypes(CMS)have been described to characterize genetic and molecular mutations in CRC patients.Through CMS,CRC patients can be categorized into four molecular subtypes of CRC by wide transcriptional genome analysis.CMS1 has microsatellite instability and mutations in CIMP and BRAF pathways.CMS2,distinguished by mutations in specific pathways linked to cellular metabolism,also has a better prognosis.CMS3 has a KRAS mutation as a hallmark.CMS4 presents mutations in fibrogenesis pathways and mesenchymalepithelial transition,associated with a worse prognosis.CMS classification can be a meaningful step in providing possible answers to important issues in CRC,such as the use of adjuvant chemotherapy in stage II,personalized first-line chemotherapy for metastasic CRC,and possible new target treatments that address specific pathways in each molecular subtype.Understanding CMS is a crucial step in personalized medicine,although prospective clinical trials selecting patients by CMS are required to pass proof-of-concept before becoming a routine clinical tool in oncology routine care. | Guillermo Valenzuela Joaquín Canepa Carolina Simonetti Loreto Solo de Zaldívar Katherine Marcelain Jaime González-Montero | 2021 | World Journal of Clinical Oncology2021，12，11： | 0 |
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