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| 1 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 2 | Superior labrum anterior to posterior lesions of the shoulder: Diagnosis and arthroscopic management显示文摘After the improvement in arthroscopic shoulder surgery,superior labrum anterior to posterior(SLAP)tears are increasingly recognized and treated in persons with excessive overhead activities like throwers.Several potential mechanisms for the pathophysiology of superior labral tears have been proposed.The diagnosis of this condition can be possible by history,physical examination and magnetic resonance imaging combination.The treatment of type 1 SLAP tears in many cases especially in older patients is non-operative but some cases need arthroscopic intervention.The arthroscopic management of type 2 lesions in older patients can be biceps tenodesis,but young and active patients like throwers will need an arthroscopic repair.The results of arthroscopic repair in older patients are not encouraging.The purpose of this study is to perform an overview of the diagnosis of the SLAP tears and to help decision making for the surgical management. | Nuri Aydin Evrim Sirin Alp Arya | 2014 | World Journal of Orthopedics2014，5，3： | 2 |
| 3 | Over-expression of p53 and c-erbB-2 oncoproteins in laryngeal carcinoma显示文摘 | Kazkayasi M Hucumenoglu S Siriner GI | 2001 | Eur Arch Otothinolaryngol2001，258，7： | 1 |
| 4 | Neuroprotective effects of preischemia subcutaneous magnesium sulfate in transient cerebral ischemia显示文摘 | Sirin BH Coskun E Yilik L | 1998 | Eur J Cardiothorac Surg1998，14，： | 1 |
| 5 | Filtering and selecting semantic web services with interactive composition techniques显示文摘 | Sirin E Parsia B Hendler J A | 2004 | IEEE Intellingent Sys-tems2004，19，4： | 1 |
| 6 | Pellet: A practical owl-dl reasoner显示文摘 | Sirin E Parsia B Grau B C | 2007 | Web Semantics: science services and agents on the World Wide Web2007，5，2： | 1 |
| 7 | Migrainous vertigo:clinical,oculographic and posturographic findings显示文摘 | Celebisoy N Cokcay F Sirin H | | 0，，： | 1 |
| 8 | Magnetic Resonance Colonography Including Diffusion-Weighted Imaging in Children and Adolescents With Inflammatory Bowel Disease: Do We Really Need Intravenous Contrast?显示文摘 | Selma Sirin Simone Kathemann Bernd Schweiger Maria L. Hahnemann Michael Forsting Thomas C. Lauenstein Sonja Kinner | 2015 | Investigative Radiology2015，，： | 1 |
| 9 | Prospective staged volume radiosurgery for large arteriovenous malformations:indications and outcomes in otherwise untreatable patients显示文摘 | Sirin S Kondziolka D Niranjan A | 2008 | Neurosurgery2008，，： | 1 |
| 10 | The role of acculturative stress on mental health symptoms for immigrant adolescents: a longitudinal investigation 显示文摘 | Sirin SR Ryce P Gupta T | 2013 | Dev Psychol2013，49，4： | 1 |
| 11 | Effects of different polishing methods on color stability of resin composites after accelerated aging 显示文摘 | Sirin Karaarslan E Bulbul M Yildiz E | 2013 | Dent Mater J2013，32，1： | 1 |
| 12 | Microstructural analyses of Cr( VI ) speciation in chromite ore processing residue(COPR) 显示文摘 | Maria C Sirine C Matthew A | 2009 | Environmental Science Technology2009，43，14： | 1 |
| 13 | Imaging of posterior fossa epidermoid tumors 显示文摘 | Sirin S Gonul E Kahraman S | 2005 | Clin Neurol Neurosurg2005，107，6： | 1 |
| 14 | Pellet:A practical OWL-DL reasoner显示文摘 | Sirin E Parsia B Grau B C | 2006 | Journal of Web Semantics2006，5，2： | 1 |
| 15 | Handover & Channel Assignment In Mobile Cellular Networks显示文摘 | Sirin Tekinay | 1991 | IEEE Communications Magazine1991，，11： | 1 |
| 16 | Handover and channel assignment in mobile cellularnetworks 显示文摘 | TEKINAY SIRIN JABBARI BIJAN | 1991 | IEEE Commun Magazine1991，29，11： | 1 |
| 17 | Pellet:a practical OWL-DL reasoner显示文摘 | Sirin E Parsia B | 2007 | Journal of Web Semantics: Science Services and Agents on the w3c2007，5，： | 1 |
| 18 | Notch in the kidney: development and disease 显示文摘 | Sirin Y Susztak K | 2012 | J Pathol2012，226，2： | 1 |
| 19 | Epithelial Notch signaling regu- lates interstitial fibrosis development in the kidneys of mice and humans显示文摘 | Bielesz B Sirin Y Si H | 2010 | J Clin Invest2010，120，11： | 1 |
| 20 | Filtering and selecting semantic Web services with interactive composition techniques 显示文摘 | Sirine E Parsia B Hendler J | 2004 | IEEE Intelli- gent Systems2004，19，4： | 1 |
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