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| 1 | Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment:a possible explanation of reduced morbidity and mortality?显示文摘 | Siroen MPC van Leeuwen PAM Nijveldt RJ | 2005 | Crit Care Med2005，3，3： | 1 |
| 2 | The clinical significance of asymmetric dimethylarginine 显示文摘 | Siroen M P Teerlink T Nijveldtr J | 2006 | Annu Rev Nutr2006，26，： | 1 |
| 3 | The clinical significance of asymmetric dimethylarginine显示文摘 | SIROEN M P TEERLINK T NIJVELDT R J | 2006 | Annu Rev Nutr2006，26，： | 1 |
| 4 | Interorgan a-mino acid exchange in humans: consequences for arginine and cit-rulline metabolism 显示文摘 | van de Poll MC Siroen MP van Leeuwen PA | 2007 | Am J Clin Nutr2007，85，： | 1 |
| 5 | Modulation of asymemetrie dinethylarginine in critically ill patients receiving intensive insulin treatment :a possible explanation of reduced morbidity and mortality ?显示文摘 | Siroen MPC van Leeuwen PAM Nijveldt RJ | 2005 | Crit Care Med2005，3，3： | 1 |
| 6 | The liver is an important inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells显示文摘 | Nijveldt RJ Teerlink T Siroen MP | 2001 | Hepatology2001，33，： | 1 |
| 7 | Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? 显示文摘 | SIROEN M P VAN LEEUWEN P A NIJVELDT R J | 2005 | Crit Care Med2005，33，3： | 1 |
| 8 | Transjugular intrahepatic portosystemic shunt-placement increases arginine/asymmetric dimethylarginine ratio in cirrhotic patients显示文摘AIM:To analyze the change of dimethylarginine plasma levels in cirrhotic patients receiving transjugular intrahepatic portosystemic shunt(TIPS).METHODS:To determine arginine,asymmetric dimethylarginine(ADMA),symmetric dimethylarginine(SDMA),and nitric oxide(NO) plasma levels,blood samples were collected from the superior cava,hepatic,and portal vein just before,directly after,and 3 mo after TIPS-placement.RESULTS:A significant increase in the arginine/ADMA ratio after TIPS placement was shown.Moreover,TIPS placement enhanced renal function and thereby decreased systemic SDMA levels.In patients with renal dysfunction before TIPS placement,both the arginine/ADMA ratio and creatinine clearance rate increased significantly,while this was not the case in patients with normal renal function before TIPS placement.Hepatic function did not change significantly after TIPS placement and no significant decline in ADMA plasma levels was measured.CONCLUSION:The increase of the arginine/ADMA ratio after TIPS placement suggests an increase in intracellular NO bioavailability.In addition,this study suggests that TIPS placement does not alter dimethylarginine dimethylaminohydrolase(DDAH) activity and confirms the major role of the liver as an ADMA clearing organ. | Michiel PC Siroen Reiner Wiest Milan C Richir Tom Teerlink Jan A Rauwerda Friedrich T Drescher Niels Zorger Paul AM van Leeuwen | 2008 | World Journal of Gastroenterology2008，14，47： | 1 |
| 9 | The liver is an important organ in the metabolism of asymmetrical dimethylarginine(ADMA) 显示文摘 | Teerlink T Siroen MP | 2003 | Clin Nutr2003，22，： | 1 |
| 10 | Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment:a possible explanation of reduced morbidity and mortality显示文摘 | van Leeuwen PA Nijveldt RJ | 2005 | Crit Care Med2005，33，3： | 1 |
| 11 | The liver is an important organ in the metabolism of asymmetrical dimethyl arginine (ADMA)显示文摘 | NIJVELDT RJ TEERLINK T SIROEN MP | | 0，，： | 1 |
| 12 | The clinical significance of asymmetric dimethylarginine显示文摘 | TEERLINK T NIJVELDT R J | 2006 | Ann Rev Nutr2006，26，： | 1 |
| 13 | The clinical signifieance of asymmetric dimethylarginine显示文摘 | Siroen MP Teerlin KT Nijveldt RJ | | 0，，0： | 1 |
| 14 | Modula-tion of asymmetric dimethylarginine in criticallyill patientsreceiving in- tensive insulin treatment: apossible explanation of reducedmor- bidity andmortality显示文摘 | Siroen MP van Leeuwen PA Nijveldt RJ | 2005 | Crit Care Med2005，33，3： | 1 |
| 15 | The clinical significance of asymmetric dimethylarginine显示文摘 | Siroen MP Teerlin KT Nijveldt RJ | | 0，，0： | 1 |
| 16 | The human liver clears both asymmetric and symmetric dimethylarginine显示文摘 | Siroen MP van der Sijp JR | 2005 | Hepatology2005，41，3： | 1 |
| 17 | The clinical signifi- cance of asymmetric dimethylarginine 显示文摘 | Siroen M P Teerlink T Nijveldt R J | 2006 | Annu Rev Nutr2006，26，： | 1 |
| 18 | Hypertaurinemia in bile duct-ligated rats aftersurgery:the effect of gut endotoxin restrietion on organ fluxes and oxidative status显示文摘 | Houdijk AP Oosterling SJ Siroen MP | 2006 | JPEN J Parenter Enteral Nutr2006，30，： | 1 |
| 19 | No compensmory upregulation of placental dimethylarginine dimethylaminohydrolase activity in preeclampsia 显示文摘 | Siroen MP Teerlink T Bolte AC | 2006 | Gynecol Obstet Invest2006，62，1： | 1 |
| 20 | Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality?显示文摘 | Siroen MP van Leeuwen PA Nijveldt RJ | 2005 | Crit Care Med2005，33，3： | 1 |
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