|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of gastric cancer in Asia: resource-stratified guidelines显示文摘 | Lin Shen Yan-Shen Shan Huang-Ming Hu Timothy J Price Bhawna Sirohi Kun-Huei Yeh Yi-Hsin Yang Takeshi Sano Han-Kwang Yang Xiaotian Zhang Sook Ryun Park Masashi Fujii Yoon-Koo Kang Li-Tzong Chen | 2013 | Lancet Oncology2013,,12: | 5 |
| 2 | A model of consumer perceptions and store loyalty intentions for a supermarket retailer显示文摘 | Niren Sirohi | 1998 | Journal of Retailing1998,,: | 2 |
| 3 | Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma显示文摘AIM:To investigate cell type specific distribution ofβ-actin expression in gastric adenocarcinoma and its correlation with clinicopathological parameters.METHODS:β-actin is a housekeeping gene,frequently used as loading control,but,differentially expresses in cancer.In gastric cancer,an overall increased expression ofβ-actin has been reported using tissue disruptive techniques.At present,no histological data is available to indicate its cell type-specific expression and distribution pattern.In the present study,we analyzedβ-actin expression and distribution in paired normal and tumor tissue samples of gastric adenocarcinoma patients using immunohistochemistry(IHC),a tissue non-disruptive technique as well as tissue disruptive techniques like reverse transcriptase-polymerase chain reaction(RT-PCR)and western blotting.Correlation ofβ-actin level with clinicopathological parameters was done using univariate analysis.RESULTS:The results of this study showed significant overexpression,at both mRNA and protein level in tumor tissues as confirmed by RT-PCR(1.47±0.13 vs2.36±0.16;P<0.001)and western blotting(1.92±0.26 vs 2.88±0.32;P<0.01).IHC revealed thatβ-actin expression is majorly distributed between epithelial and inflammatory cells of the tissues.Inflammatory cells showed a significantly higher expression compared to epithelial cells in normal(2.46±0.13 vs 5.92±0.23,P<0.001),as well as,in tumor tissues(2.79±0.24 vs6.71±0.14,P<0.001).Further,comparison of immunostaining between normal and tumor tissues revealed that both epithelial and inflammatory cells overexpressβ-actin in tumor tissues,however,significant difference was observed only in inflammatory cells(5.92±0.23vs 6.71±0.14,P<0.01).Moreover,combined expression in epithelial and inflammatory cells also showed significant increase(4.19±0.15 vs 4.75±0.14,P<0.05)in tumor tissues.In addition,univariate analysis showed a positive correlation ofβ-actin level of inflammatory cells with tumor grade(P<0.05)while epithelial cells exhibited negative correlation(P>0.05).CONCLUSION:In gastric cancer,β-actin showed an overall higher expression predominantly contributed by inflammatory or tumor infiltrating immune cells of the tissue microenvironment and correlates with tumor grade. | Shafqat A Khan Monica Tyagi Ajit K Sharma Savio G Barreto Bhawna Sirohi Mukta Ramadwar Shailesh V Shrikhande Sanjay Gupta | 2014 | World Journal of Gastroenterology2014,20,34: | 2 |
| 4 | Evolution of pancreatoduodenectomy in a tertiary cancer center in India: Improved results from service reconfiguration显示文摘 | Shailesh V. Shrikhande Savio George Barreto B.A. Somashekar Kunal Suradkar Guruprasad S. Shetty Sanjay Talole Bhawna Sirohi Mahesh Goel Parul J. Shukla | 2013 | Pancreatology2013,,1: | 2 |
| 5 | Design, analysis and hover performance of a rotary wing micro air vehicle显示文摘 | BOHORQUEZ F SAMUEL P SIROHI J | 2003 | Journal of the American Helicopter Society2003,48,2: | 1 |
| 6 | Early response to platinum-based first-line chemotherapy in non-small cell lung cancer may predict survival显示文摘 | Sirohi B Ashley S Norton A | 2007 | J Thorac Oncol2007,2,8: | 1 |
| 7 | Comparison of newpatients with Bence-Jones, IgG and IgA myeloma receivingsequential therapy: the need to regard these immunologicsubtypes as separate disease entities with specific prognostiecriteria 显示文摘 | Sirohi B Powles R Kulkami S | 2001 | Bone Marrow Transplant2001,28,1: | 1 |
| 8 | Delayed proximal ureteric stricture formation after complex partial nephreetomy显示文摘 | Reyes JM Canter DJ Sirohi M | 2012 | BJU Int2012,109,4: | 1 |
| 9 | Epidemiology and Outcomes Research for MGUS,Myeloma and Amyloidosis 显示文摘 | Sirohi B Powles R | 2006 | Eur J Cancer2006,42,11: | 1 |
| 10 | Epidemiology and outcomes research for MGUS,myeloma and amyloidosis显示文摘 | Sirohi B Powles R | 2006 | Enr J Cancer2006,42,: | 1 |
| 11 | Platinum-based chemotherapy in triple-negative breast cancer显示文摘 | Sirohi B Arnedos M Popat S | 2008 | Ann Oncol2008,19,11: | 1 |
| 12 | New aspects and strategies for methane mitigation from ruminants显示文摘 | Sanjay Kumar Prasanta Kumar Choudhury Maria Dolores Carro Gareth Wyn Griffith Sumit Singh Dagar Monica Puniya Serena Calabro Sreenivas Rao Ravella Tejpal Dhewa Ramesh Chandra Upadhyay Sunil Kumar Sirohi Shivlal Singh Kundu Metha Wanapat Anil Kumar Puniya | 2014 | Applied Microbiology and Biotechnology2014,,: | 1 |
| 13 | Platinum-based chemo therapy in triple-pegative breast cancer显示文摘 | Sirohi B Arnedos M Popat S | 2008 | Ann Oncol2008,19,: | 1 |
| 14 | Frequency Domain Modeling of a Piezohydraulic Actuator显示文摘 | Sirohi J Cadou C Chopra I | 2005 | Journal of Intelligent Material Systems and Structures2005,16,6: | 1 |
| 15 | White-light interferome-try with polarization phase-shifter at the input of the interferometer显示文摘 | SUJA H S KOTHIYAL M P SIROHI R S | 2000 | Journal of Modern Optics2000,47,6: | 1 |
| 16 | Platinum based chemother- apy in triple negative breast cancer 显示文摘 | Sirohi B Arnedos M Popat S | 2008 | Ann Oncol2008,19,11: | 1 |
| 17 | Macrofollicular variant of papillary carcinoma, a potential diagnostic pitfall: A report of two cases including a review of literature 显示文摘 | Policarpio-Nicolas ML Sirohi D | 2013 | Cytojournal2013,10,: | 1 |
| 18 | Multiple myeloma 显示文摘 | Sirohi B Powles R | 2004 | Lancet2004,363,9412: | 1 |
| 19 | Frequency Domain Modeling of a Piezohydraulic Actuator显示文摘 | Sirohi J Cadou C Chopra I | 2005 | Journal of Intelligent Material Systems and Structures2005,16,48: | 1 |
| 20 | Gemcitabine, cisplatin and methylprednisolone ( GEM - P) with or without Rituximab in relapsed and refractory patients with diffuse large B cell lymphoma (DLBCL) 显示文摘 | Sirohi B Cunningham D Norman A | 2007 | Hematology2007,12,2: | 1 |