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| 1 | Sarcopenia in heart failure: mechanisms and therapeutic strategies显示文摘长期的心失败(CHF ) 是一个高度流行的条件在之中老并且与可观的病态, institutionalization 和死亡被联系。在它的先进阶段, CHF 被肌肉质量和力量的损失经常伴随。Sarcopenia 是活跃地与大量不利健康结果由于它的协会在最近的年里被学习了的衰老老人症候群。这评论的目标是讨论在 CHF 和 sarcopenia 之间的关系,与分享的 pathophysiological 小径和处理的一个焦点。营养不良,全身的发炎,内分泌的不平衡,和氧化应力看起来连接 sarcopenia 和 CHF。在肌肉发达的水平, ubiquitin proteasome 系统,发信号的 myostatin,和 apoptosis 的改变在 sarcopenia 和 CHF 被描述了并且能在肌肉质量和功能的损失起一个作用。阻碍肌肉在 CHF 病人浪费的前进的可能的治疗学的策略包括变换血管收缩素的酶禁止者和 β 的蛋白质和维生素 D 补充,结构化的物理锻练,和管理; -blockers。有生长荷尔蒙,睾丸激素,和 ghrelin 的神经质的补充也作为潜在的治疗被讨论。 | Agnese Collamati Emanuele Marzetti Riccardo Calvani Matteo Tosato Emanuela D'Angelo Alex N Sisto Francesco Landi | 2016 | Journal of Geriatric Cardiology2016，13，7： | 25 |
| 2 | 经腹机器人辅助腹腔镜肾部分切除术治疗T2期肾肿瘤的国际多中心临床研究显示文摘目的通过国际多中心研究探讨临床T2期肾肿瘤行经腹机器人辅助腹腔镜肾部分切除术的安全性及有效性。方法回顾性分析2012年1月至2017年12月国际19家泌尿中心378例临床T2期肾肿瘤行经腹机器人肾部分切除术和经腹机器人根治性肾切除术患者的临床资料。根据手术方式不同,分为部分切除组和根治组。部分切除组159例,男118例,女41例;年龄(59.3±13.2)岁,体重指数(28.7±5.4) kg/m^2,术前GFR (77.3±22.1)ml/min;肿瘤位于左侧72例,右侧87例;肿瘤直径(83±16)mm;R.E.N.A.L.评分(8.6±2.2)分。根治组219例,男156例,女63例;年龄(62.0±12.9)岁,体重指数(28.7±6.1) kg/m^2,术前GFR (71.4±20.3)ml/min;肿瘤位于左侧112例,右侧105例,双侧2例;肿瘤直径(92±25)mm;R.E.N.A.L.评分(9.7±1.5)分。两组患者性别、体重指数、肿瘤位置的差异均无统计学意义(P〉0.05)。部分切除组患者年龄、肿瘤直径、R.E.N.A.L.评分均低于根治组(P〈0.05),术前GFR优于根治组(P=0.012)。比较两组围手术期资料、肿瘤病理类型、随访时间、复发时间及术后GFR等。结果378例手术均顺利完成。部分切除组手术时间中位值150 min(65-353 min),短于根治组[180 min(85-361 min),P〈0.001],术中出血量中位值150 ml(40-3 000 ml),多于根治组[100 ml (10-1 100 ml),P〈0.001]。术中并发症发生率部分切除组为5.7%(9/159),根治组为3.2%(7/219),两组差异无统计学意义(P=0.240)。部分切除组术后并发症发生率高于根治组[19.5%(31/159)与10.5%(23/219),P=0.014],但≥3级并发症发生率的差异无统计学意义[4.4%(7/159)与2.3%(5/219),P=0.246]。部分切除组无复发生存率高于根治组[91.4%(117/128)与81.9%(167/204),P=0.013]。部分切除组术后GFR降低值16.9 ml/min(10.4-84.7 ml/min)明显少于根治组29.0 ml/min(14.0-54.0 ml/min),肾部分切除术更利于术后肾功能的保护(P〈0.001)。结论临床T2期肾肿瘤行机器人肾部分切除术可获得有效的肿瘤控制率,同时可以更好地保护肾功能,可作为临床T2期肾肿瘤有效的手术方式。 | 过菲 张超 王富博 王林辉 杨庆 叶华茂 吕晨 肖成武 汪洋 Giuseppe Simone Ithaar Derweesh Andrea Minervini Daniel Eun Francesco Porpiglia Sisto Perdona James Porter Matteo Ferro Alexandre Mottrie Robert Uzzo Luigi Schips Wesley White Ken Jacobsohn Prokar Dasgupta Riccardo Autorino Clayton Lau Chandru Sundaram Umberto Capitanio 孙颖浩 杨波 | 2018 | 中华泌尿外科杂志2018，39，6： | 8 |
| 3 | Comparison of perioperative parameters in one-handed rotational phacoemulsification versus conventional phacoemulsification and femtosecond laser-assisted cataract surgery显示文摘AIM:To compare perioperative parameters of one-handed rotational phacoemulsification technique(one-handed phaco-roll)with each of other two techniques,“Divide et Conquer”and femtosecond laser-assisted cataract surgery(FLACS)METHODS:In this retrospective and comparative cohort study,eyes with uncomplicated cataract(nuclear density grade 2 to 3)treated routinely with one-handed phacoroll(n=23;Group 1)or“Divide et Conquer”(n=23;Group 2)or FLACS(n=23;Group 3)were enrolled.Intraoperative parameters including effective phaco-time(EPt),ultrasound time(USt),aspiration time,surgical time,phacoemulsification(phaco)-power,balanced salt solution(BSS)use,cumulative dissipated energy(CDE)were recorded and compared.Clinical outcomes including best corrected visual acuity(BCVA),corneal endothelial cell density(ECD),endothelial cell loss(ECL),central corneal thickness(CCT)and central macular thickness(CMT),were assessed and compared pre-operatively and at 1mo after surgery.RESULTS:Aspiration and surgical time,and BSS used were lower in Group 1(P<0.01)than other groups.EPt,phaco-power and CDE were lower in Group 1(P<0.05)than Group 2 but not significantly different from Group 3.In Group 1,USt was lower(P<0.05)than Group 2 but higher(P<0.05)than Group 3.BCVA improved in all groups without significant difference between Group 1 and the other ones.No significant differences regarding all post-operative morphologic outcomes(ECD,ECL,CCT,CMT)were reported.No clinical complications occurred.CONCLUSION:One-handed phaco-roll seems to be less time-consuming than“Divide et Conquer”and FLACS and less energy-consuming than“Divide et Conquer”.Furthermore,one-handed phaco-roll seems to have an equal safety profile compared to the other two techniques. | Samuele Gigliola Giancarlo Sborgia Alfredo Niro Carmela Palmisano Pasquale Puzo Gianluigi Giuliani Luigi Sborgia Dario Sisto Valentina Pastore Claudio Furino Rossella Donghia Alessandra Sborgia Francesco Boscia Giovanni Alessio | 2021 | International Journal of Ophthalmology(English edition)2021，14，12： | 2 |
| 4 | Complete knee dislocation:a follow-up study of operative treatment显示文摘 | Sisto DJ Warren RF | 1985 | Clin Orthop1985，198，： | 1 |
| 5 | Tumor necrosis factor inhibitom block apoptosis of human epithelial cells of the salivary glands 显示文摘 | Sisto M D Amore M Caprio S | 2009 | Ann NY Acad Sci2009，1171，： | 1 |
| 6 | Modified constraint induced therapy:a randomized feasibility and efficacy study显示文摘 | Page SJ Sisto SA Levine P | 2001 | Journal of rehabilitation research and development2001，38，5： | 1 |
| 7 | A randomized efficacy and feasibility study of imagery in acute stroke显示文摘 | Page SJ Levine P Sisto SA | 2001 | Cliu Rehabil2001，15，3： | 1 |
| 8 | Efficacy of modified constraint in duced movement therapy in chronic stroke: a single blinded random ized controlled trial显示文摘 | Page SJ Sisto S Levine P | 2004 | Arch Phys Med Rehabil2004，85，： | 1 |
| 9 | Efficacy of modified constraint - induced movement therapy in chronic stroke : a singe - Blinded controlled trial显示文摘 | Page SJ Sisto S Levine P | 2004 | Arch Phys Med Rehahil2004，85，1： | 1 |
| 10 | A deadlock detection tool for concurrent java programs显示文摘 | DEMARTINI C IOSIF R SISTO R | 1999 | Software:Practice and Experience1999，29，7： | 1 |
| 11 | Genetic structure of the Pleurotus eryngii species-complex 显示文摘 | de Gioia T Sisto D Rana G L | 2005 | Mycol Res2005，109，： | 1 |
| 12 | Efficacy of modified constraint-induced movement therapy in chronic stroke:a single-blinded randomized controlled trial显示文摘 | Page SL Sisto S Levine P | 2004 | Arch Phys Med Rehabil2004，85，1： | 1 |
| 13 | Paraoxonase producing PON 1 gene M/L 55 poly morphism is related to autopsy-verified artery-wall atherosclerosis 显示文摘 | Malin R Jarvnen O Sisto T | 2001 | Atherosclerosis2001，157，2： | 1 |
| 14 | Mental practice combined with physical practice for upper-limb motor deficit in subacute stroke显示文摘 | Page SJ Levine P Sisto SA et a1 | | 0，，08： | 1 |
| 15 | Methylenetetrahydrofolate reductase gene C677T mutation is related to the defects in the internal elastic lamina of the artery wall显示文摘 | Hamelahti P Jarvinen O Sisto T | 2002 | Eur J Clin Invest2002，2，17： | 1 |
| 16 | Stroke patients' and therapists' opinions of constraint-induced movement therapy显示文摘 | Page SJ Levine P Sisto S | 2002 | Clin Rehabil2002，16，1： | 1 |
| 17 | Atherosclerosis of the visceral arteries显示文摘 | Jarvinen O Laurikka J Sisto T | 1993 | Surg Clin North Am1993，73，5： | 1 |
| 18 | Computational aerodynamics of oscillating cascade with the evolution of stall显示文摘 | Sisto F WU Wen-quan | 1989 | AIAA J1989，27，4： | 1 |
| 19 | The effects of confinement on motivation to exercise in young dairy calves显示文摘 | Sisto A M Friend T H | 2001 | Appl Anim Behav Sci2001，73，： | 1 |
| 20 | Guaiacol hydrodeoxygenation on MoS2 catalysts:Influence of activated carbon supports显示文摘 | Ruiz P E Frederick B G De Sisto W J | | 0，，： | 1 |
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