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| 1 | Electroacupuncture on PC6 Prevents Opioid-Induced Nausea and Vomiting after Laparoscopic Surgery显示文摘Objective:To investigate the treatment time dependence of electroacupuncture(EA) on Neiguan (PC6) for preventing postoperative nausea and vomiting(PONV).Methods:One hundred and seventy-eight patients,who had received intravenous patient-controlled analgesia(PCA) with Fentanyl,were assigned randomly to three groups using random numbers:a pre-operative EA group(PrEA),a post-operative EA group(PoEA),and a non-acupuncture control group(NC).An anesthetist evaluated the incidence and severity of nausea and vomiting for 48 h after surgery blindly.The main outcomes were severity and freguency of PONV,which were measured with a self-reported questionnaire and a confirmation from the anesthetist.The data were analyzed with ANOVA and Z-test.Results:The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery(P<0.01,P<0.05).The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group(P<0.05).The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting(P<0.05).The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups(P<0.05).Conclusions:EA on PC6 is effective in the prevention of PONV,and pre-operative acupuncture is more effective than post-operative acupuncture. | Siwoo Lee Myeong Soo Lee Deok Hwa Choi Su Kyung Lee | 2013 | Chinese Journal of Integrative Medicine2013，19，4： | 32 |
| 2 | Genome-wide DNA methylation profiling reveals candidate biomarkers and probable molecular mechanism of metabolic syndrome显示文摘Although aberrant DNA methylation changes are significantly associated with the pathogenesis of many diseases,little is known about the molecular mechanisms underlying interactions between DNA methylation and gene expression in metabolic syndrome(MetS).The aim of this study was to identify biomarkers and molecular mechanisms regulated by DNA methylation in MetS.We profiled genome-wide DNA methylation using the Infinium MethylationEPIC BeadChIP and characterized the transcriptome by RNA sequencing in our study population comprised of subjects with MetS(n=11)and controls(n=9). | Su-Jin Baek Hyo-Jeong Ban Sang-Min Park Soo Yeon Kim Siwoo Lee Hee-Jeong Jin | 2022 | Genes & Diseases2022，9，4： | 2 |
| 3 | Investigation of prodromal features in metabolic syndrome based on transcriptome analysis显示文摘Metabolic syndrome(MetS)is a complex condition that significantly increases the risk of several diseases,including heart disease and diabetes.Patients with MetS show both pro-inflammatory and pro-thrombotic states;however,the state that takes precedence in MetS progression is unclear. | Sang-Min Park Musun Park Hyo-Jeong Ban Su-Jin Baek Soo Yeon Kim Siwoo Lee Hee-Jeong Jin | 2023 | Genes & Diseases2023，10，3： | 0 |
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