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75篇 您的检索式:作者名="Skerra"
    题名 作者 年代 出处 被引量
1A novel type of receptor protein,base on the lipocalin scaffold,with specificity for digoxigenin显示文摘SCHLEHUBER S BESTE G SKERRA A 2000J Mol Biol2000,297,:1
2Comparative ligand binding analysis of ten human lipocalins 显示文摘Breustedt DA Schonfeld DL Skerra A 2006Biochim Bio phys Acta2006,1764,:1
3Tuning ligand affinity,specificity and folding stability of an engineered lipocalin variant-also-called 'anticalin'-using a molecular random approach显示文摘SCHLEHUBER S SKERRA A 2002Biophy Chem2002,96,:1
4Crystallographic analysis of an 'anticalin'with tailored specificity for fluorescenin reveals high structural plasticity of the lipocalin loop region显示文摘INGO P K BESTE G SKERRA A 2003Proteins:Struc Func and Cene2003,52,:1
5Phosphorothioate Primers Improve the Amplification of DNA Sequences by DNA Polymerases with Proof-reading Activity显示文摘Skerra A 1992Nucleic Acids Res1992,20,:1
6A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of F (ab) fragments and leads to improved recombinant immunoglobulin stability显示文摘Kramer K Fiedler M Skerra A 2002Biosens Bioelectron2002,17,4:1
7The crystal structure of the human (S100A8/S100A9) 2 heterotetramer,calprotectin,illustrates how conformational changes of interacting alpha helices can determine specific association of two EF-hand proteins显示文摘Korndorfer IP Brueckner F Skerra A 0,,05:1
8Assembly of a funtional immunoglobulin Fv fragment in Escherichia coli显示文摘 Pluckthun A 1988Science1988,240,4855:1
9Baeterial expression of immunoglobulin fragments 显示文摘Skerra A 1993CurrOpinlmmunol1993,5,:1
10Comparative ligand-bind- ing analysis of ten human lipocalins 显示文摘Breustedt DA Schtinfeld DL Skerra A 2006Biochim Biophys Acta2006,1764,2:1
11A generic strategy for subcloning antibody variable regions from the scFv phage display vector pCANTAB 5 E into pASK85 permits the economical production of F(ab) fragments and leads to improved recombinant immunoglobulin stability显示文摘Kramer K Skerra A Hock B 2002Biosens Bioelectron2002,17,4:1
12Binding proteins from alternative scaffolds显示文摘Nygren PA Skerra A 0,,1:1
13Mutagenesis of a flexible loop in streptavidin leads to higher affinity for the strep-tag Ⅱ peptide and improved performance in recombinant protein purification显示文摘VOSS S SKERRA A 1997Protein Eng1997,10,8:1
14Structual mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin显示文摘INGO P K SCHLEHUBER S SKERRA A 2003J Mol Biol2003,330,:1
15The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins显示文摘SCHMIDT TG SKERRA A 2007Nat Protoc2007,2,6:1
16The random peptide hbrary assisted engineering of a C-terminal amnity peptide, useful for the detection and purification of a functional Ig Fv fragment显示文摘Schmidt TG Skerra A 1993Protein Eng1993,6,1:1
17Engineered protein scaffolds as next-generation antibody therapeutics显示文摘Michaela Gebauer Arne Skerra 2009Current Opinion in Chemical Biology2009,,3:1
18Mutagenesis of a flexible loop in streptavidin leads to higher affinity for the Strep-tag II peptide and improved performance in recombinant protein purification显示文摘Voss S Skerra A 1997Protein Eng1997,10,8:1
19Assembly of functional immunoglobulin Fv fragment in Escherichia coli显示文摘Skerra A Pluckthun A 1988Science1988,240,:1
20A novel type of receptor protein,based on the lipocalin scaffold,with specificity for digoxigenin显示文摘 Beste G Skerra A 2000J Mol Biol2000,297,5:1
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