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379篇 您的检索式：作者名="Skinner E"

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	题名	作者	年代	出处	被引量
1	Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection显示文摘AIM: To test antibiotic-loaded coating for efficacy in reducing bacterial biofilm and development of osteomyelitis in an orthopaedic model of implant infection. METHODS: Phosphatidylcholine coatings loaded with 25% vancomycin were applied to washed and sterilized titanium wires 20 mm in length. A 10 mm segment was removed from rabbit radius(total = 9; 5 coated, 4 uncoated), and the segment was injected with 1 × 106 colony forming units(CFUs) of Staphylococcus aureus(UAMS-1 strain). Titanium wires were inserted throughthe intramedullary canal of the removed segment and into the proximal radial segment and the segment was placed back into the defect. After 7 d, limbs were removed, X-rayed, swabbed for tissue contamination. Wires were removed and processed to determine attached CFUs. Tissue was swabbed and streaked on agar plates to determine bacteriological score.RESULTS: Antibiotic-loaded coatings resulted in significantly reduced biofilm formation(4.7 fold reduction in CFUs; P < 0.001) on titanium wires and reduced bacteriological score in surrounding tissue(4.0 ± 0 for uncoated, 1.25 ± 0.5 for coated; P = 0.01). Swelling and pus formation was evident in uncoated controls at the 7 d time point both visually and radiographically, but not in antibiotic-loaded coatings.CONCLUSION: Active antibiotic was released from coated implants and significantly reduced signs of osteomyelitic symptoms. Implant coatings were well tolerated in bone. Further studies with additional control groups and longer time periods are warranted. Antibiotic-loaded phosphatidylcholine coatings applied at the point of care could prevent implant-associated infection in orthopaedic defects.	Jessica Amber Jennings Karen E Beenken Robert A Skinner Daniel G Meeker Mark S Smeltzer Warren O Haggard Karen S Troxel	2016	World Journal of Orthopedics2016，7，8：	2
2	Gene translocation in poxvirus:the fowlpox virus thymidine kinase gene isflanked by 15 bpdirect repeats and occupied by the locus which in vaccine virus is occupied by the ribonucleotide reductase large subunit gene 显示文摘	Binns M M Boursneii M E Skinner M A	1992	Virus Res1992，24，2：	1
3	Improved acid neutralisation capacity assessment of iron carbonates by titration and theoretical calculation显示文摘	Weber P A Thomas J E Skinner W M	2004	Applied Geochemistry2004，19，：	1
4	Leukemia inhibitory factor (LIF) promotes the primordial to primary follicle transtion in rat ovaries显示文摘	Nilsson E E Kezele P Skinner M K	2002	Mol Cell Endocrinol2002，188，：	1
5	An information privacy taxonomy for collaborative environments 显示文摘	Skinner G Han S Chang E	2006	Information management & com- puter security2006，14，4：	1
6	Association of postoperative pulmonary complications with delayed mobilization following major abdominal surgery: an observational cohort study Physiotherapy显示文摘	HAINES K J SKINNER E H BERNEY S	2013	The Austin Health POST Study Investigators2013，99，2：	1
7	Airport choice: an empirical study 显示文摘	SKINNER R E	1976	Transportation Engineering Journal1976，102，：	1
8	Uri- nary functional outcome following radical cystoprosta- tectomy and ileal neobladder reconstruction in male pa- tients显示文摘	Ahmadi H Skinner E C Simma-Chiang V	2013	J Urol2013，189，5：	1
9	Which patients are suitable for continent diversion or bladder substitution following cystectomy or other definitive local treatment?显示文摘	SKINNER D G STUDER U E OKADA K	1995	Int J Urol1995，2，2：	1
10	Motivation in the classroom: reciprocal effects of teacher behavior and student engagement across the school year显示文摘	SKINNER E A BELMONT M J	1993	Journal of Educational Psychology1993，85，4：	1
11	The drained residual strength of co- hesive soils显示文摘	Lupini J F Skinner A E Waughan P R	1981	Geotechnique1981，31，2：	1
12	An evaluation of fructooligosaccharide in diets for broiler chickens and effects onsalmonellae contamination of carcasses显示文摘	WALDROUP A L SKINNER J T HIERHOLZER R E	1993	Poultry Sci1993，72，：	1
13	A prospective study of folate intake and the risk of pancreatic cancer in men and women显示文摘	Skinner H G Michaud D S Giovannueci E L Rimm E B Stampfer M J Willett W C	2004	Am J Epidemiol2004，160，：	1
14	Analytical farfield divergence angle of a truncated Gaussian beam显示文摘	DRE'GE E M SKINNER N G BYME D M	2000	Appl Opt2000，39，27：	1
15	Options in replacement cystoplasty following radical cystectomy: high hope or successful reality 显示文摘	Martins F E Bennett C J Skinner D G	1995	J Urol1995，153，5：	1
16	Connectivity and piezoelectric-pyroelectric composites显示文摘	NEWNHAM R E SKINNER D P CROSS L E	1978	Mater Res Bull1978，13，：	1
17	Options in replacement cystoplasty following radical cystectomy:high hopes or successful reality显示文摘	Martins F E Bennett C J Skinner D G		0，，05：	1
18	Searching for the structure of coping: A review and critique of category systems for classifying ways of coping 显示文摘	Skinner E A Edge K Ahman J	2003	Psychological Bulletin2003，129，：	1
19	Completion of the sequence of the genome of the coronavirus avian infectious bronchitis virus 显示文摘	BOURSNELL M E G BROWN T D K SKINNER M	1987	J Gen Virol1987，68，：	1
20	Connectivity-pyroelectriccomposites 显示文摘	Newnham R E Skinner D P Cross L E	1978	Mater Res Bull1978，13，7：	1

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