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36篇 您的检索式:作者名="Slee E"
    题名 作者 年代 出处 被引量
1Ordering the cytochrome c-initiated caspase cascade:hineratchical activation of caspases-2,-3,-6,-7,-8,and -10 in a caspase-9-dependent manner显示文摘Slee E A Harte M T Kluck R M 1999J Cell Biol[J]1999,144,:1
2Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by Caspase-3:a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release显示文摘Slee E Keogh S Martin S 2000Cell Death Differ2000,7,6:1
3To die or not to die:how does p53 decide? 显示文摘SLEE E A O'CONNOR D J LU X 2004Oncogene2004,23,16:1
4The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization显示文摘Slee E A Gillotin S Bergamaschi D 2004Oncogene2004,23,56:1
5The ASPP family: deciding between life and death after DNA damage显示文摘 Lu X 2003Toxicol Lett2003,139,23:1
6早期将抗生素由静脉转为口服治疗严重社区获得性肺炎:多中心随机试验显示文摘目的比较早期由静脉转换成口服抗生素与常规静脉使用7天抗生素治疗严重社区获得性肺炎(CAP)的疗效。设计多中心随机对照试验。地点荷兰5家教学医院和2所大学的医学中心。参加者非 ICU 住院的严重 CAP 患者302例,其中265例满足研究要求。干预静脉抗生素治疗3天,病情稳定后换成口服抗生素,或静脉使用抗生素治疗7天。主要评价结果临床治愈和住院天数。结果 302例患者被随机分组(平均年龄69.5岁,标准差14.0),肺炎严重度评分平均112.7(26.0)。37例患者因为提前3天退出而未纳入分析,对其余265例患者进行分析研究。第28天的死亡率在干预组是4%,对照组是6%(平均差2%,95%可信区间-3%~8%)。临床治愈率在干预组是83%,对照组是85%(2%;-7%~10%)。与对照组相比,干预组患者静脉治疗时间为3.4天[3.6(1.5)比7.0(2.0)天;2.8~3.9],患者住院天数减少1.9天[9.6(5.0)比11.5(4.9)天;0.6~3.2]。结论早期将抗生素由静脉应用转换成口服治疗严重 CAP 是安全的,并且可以减少住院时间2天。试验注册号临床试验 NCT00273676。Jan Jelrik Oosterheert Marc J M Bonten Margriet M E Schneider Erik Buskens Jan-Willem J Lammers Willem M N Hustinx Mark H H Kramer Jan M Prins Peter H Th J Slee Karin Kaasjager Andy I M Hoepelman 王伟巍(译) 童朝辉(校) 2007英国医学杂志中文版2007,10,2:1
7The viral nucleocapsid protein of transmissible gastroenteritis coronavirus(TGEV) is cleaved by caspases-6 and caspases-7 during TGEV-induced apoptosis显示文摘Eleouet J F Slee E A Saurini F 2000J Virol2000,74,9:1
8A complex barcode underlies the heterogeneous response of p53 to stress 显示文摘Murray-Zmijewski F Slee E A Lu X 2008Nat Rev Mol Cell Biol2008,9,9:1
9Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner显示文摘Slee E A Harte M T Kluck R M 1999J Cell Biol1999,144,2:1
10The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization显示文摘 GILLOTIN S GILLOTIN D 2004Gncogene2004,23,:1
11The viral nucleocapsid protein of transmissible gastroenteritis virus(TGEV) is cleaved by Caspase-6 and -7 during TGEV-induced apoptosis显示文摘Eleouet J F Slee E A Saurini F 2000J Virol2000,74,:1
12The N-terminus of a Novel Isofonn of Human iASPP Is Required for Its Cytoplasmic Loealization 显示文摘Slee E A Gillotin S Bergamaschi D 2004Oncogene2004,23,:1
13Acoustic and seismic modalities for unattended ground sensors 显示文摘Slee G E Ladd M D McDonald T S 1999SPIE1999,37,131:1
14Ordering the cytochrome c-initiated caspase cascade:hierarchical activation of caspases-2,-3,-6,-7,-8,and -10 in a caspase-9-dependent manner显示文摘Slee E A Harte M T Kluck R M 1999J Cell Biol1999,144,2:1
15Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -lOin a caspase-9 -dependent manner显示文摘Slee E A Harte M T Kluck R M 1999J Cell Bioi1999,144,2:1
16The viral nuclecapsid protein of transmissible gastroenteritis coronavirus (TGEV) is cleaved by caspase-6 and-7 during TGEV induced apoptosis显示文摘Eleouet J F Slee E A Saurini F 2000Virol2000,74,9:1
17A complex barcode underlies the heterogeneous response of p53 to stress 显示文摘Murray-Zmijewski F Slee E A Lu X 2008Nat Rev Mol Cell Biol2008,9,9:1
18The ASPP family: deciding between life and death after DNA damage显示文摘Slee E A Lu X 2003Toxicol Lett2003,139,23:1
19Phosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro- apoptotic function显示文摘Godin-Heymann N Wang Y Slee E 2013PLoS One2013,8,82:1
20Phosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro-apoptotic function显示文摘Godin-Heymann N Wang Y Slee E 2013Plos One2013,8,82:1
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