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| 1 | Associations between cardiac arrhythmia,incident disability in activities of daily living and physical performance:the ILSA study显示文摘Background Cardiac arrhythmias are common conditions in older people.Unfortunately,there is limited literature on associations between cardiac arrhythmias and physical performance or disability.We therefore aimed to prospectively investigate associations between cardiac arrhythmias and changes in disability and physical performance during 8 years of follow-up,using data from the Italian Longitudinal Study on Aging(ILSA).Methods Cardiac arrhythmias diagnosis was posed through a screening phase,confirmed by a physician.The onset of disability in activities of daily living(ADL)and the changes in several physical performance tests during follow-up were considered as outcomes.Fully-adjusted and propensity-score Cox Proportional Hazard models and mixed models were used for exploring associations between cardiac arrhythmia and the outcomes of interest.Results The prevalence of cardiac arrhythmia at baseline was 23.3%.People reporting cardiac arrhythmia at the baseline were significantly older,more frequently male,smokers and reported a higher presence of all medical conditions investigated(hypertension,heart failure,angina,myocardial infarction,diabetes,stroke),but no difference in dementia,Parkinsonism,cognitive or mood disorder.Cardiac arrhythmia at baseline was significantly associated with the incidence of disability in ADL(HR=1.23;95%:CI:1.01–1.50;P=0.0478 in propensity score analyses;HR=1.28;95%CI:1.01–1.61;P=0.0401 in fully adjusted models).Cardiac arrhythmia at baseline was also associated with a significant worsening in balance test(P=0.0436).Conclusions The presence of cardiac arrhythmia at baseline was associated with a significant higher risk of disability and of worsening in some physical performance tests,particularly those relating to balance.Screening and frequently assessing physical performance in older people affected by cardiac arrhythmia can be important to prevent a loss of physical performance,with further,potential,complications of medical management. | Marianna Noale Nicola Veronese Lee Smith Andrea Ungar Stefano Fumagalli Stefania Maggi the Italian Longitudinal Study on Aging Working Group | 2020 | Journal of Geriatric Cardiology2020，17，3： | 3 |
| 2 | Painful sensory polyneuropathy associated with impaired glucose tolerance显示文摘 | Singleton JR Smith AG Bromberg MB | 2001 | Muscle Nerve2001，24，： | 1 |
| 3 | Local thrombolytic therapy in deep cerebral venous thrombosis显示文摘 | Smith AG Comblath WT Devikis JP | 1997 | Neurology1997，48，6： | 1 |
| 4 | Conjugated metallopoly- mers for fluorescent turn-on detection of nitric oxide 显示文摘 | Smith RC Tennyson AG Won AC | 2006 | Inorg Chem2006，45，23： | 1 |
| 5 | Increasing incidence of Crohn's disease in Victorian children显示文摘 | Phavichitr N Cameron DJ Catto- Smith AG | 2003 | J Gastroenterol Hepatol2003，18，： | 1 |
| 6 | Gamma knife radiosurgery for trigeminal neuralgia: experience at the Barrow Neurological Institute 显示文摘 | Shetter AG Smith KA | 1999 | Stereotact Funct Neurosurg1999，73，14： | 1 |
| 7 | Comprehensive anal-ysis of HLA-A, HLA-B, HLA-C, HLA-DRB1,and HLA-DQB1 lociand squamous cell cervical cancer risk显示文摘 | Madeleine MM Johnson LG Smith AG | 2008 | Cancer Res2008，68，9： | 1 |
| 8 | Man- agement of hemorrhage after percutaneous renal surgery 显示文摘 | Kessaris DN Bellman GC Pardalidis NP Smith AG | 1995 | Urol1995，153，60： | 1 |
| 9 | New prospects for human stem-cell therapy in the nervous system显示文摘 | Smith AG | 1999 | Trends Neurosci1999，22，8： | 1 |
| 10 | Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors显示文摘 | Kawaguchi J Mee PJ Smith AG | 2005 | Bone2005，36，5： | 1 |
| 11 | Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides 显示文摘 | Smith AG Heath JK Donaldson DD | | Nature0，336，6200： | 1 |
| 12 | Impaired glucose tolerance and neuropathy 显示文摘 | Smith AG Singleton JR | 2008 | Neurologist2008，14，1： | 1 |
| 13 | Nucleic acid concentrations in normal human plasma 显示文摘 | Smith AG | 1972 | Clin Chem1972，18，： | 1 |
| 14 | Identification of insulinproducing cells derived from embryonic stem cells by zincchelating diathizone显示文摘 | Shiroi A Smith AG Thomson C | 2002 | Stem Cells2002，20，： | 1 |
| 15 | Surviving collapsed structure entrapment after earthquakes: a ' time-to rescue' analysis显示文摘 | Macintyre AG Barbera JA Smith ER | 2006 | Prehosp Disaster Meal2006，21，： | 1 |
| 16 | Local thrombolytic therapy in deep cerebral venous thrombosis显示文摘 | Cornblath WT Deveikis JP | 1997 | Neurology1997，48，6： | 1 |
| 17 | Polymer-bound dirhodium tetracarboxylate films for fluorescent detection of nitric oxide 显示文摘 | Smith RC Tennyson AG Lippard SJ | 2006 | Inorg Chem2006，45，16： | 1 |
| 18 | Increased prevalence of impaired glucose tolerance in patients with painful sensory neuropathy显示文摘 | Singleton JR Smith AG | 2001 | Diabetes Care2001，24，： | 1 |
| 19 | Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells 显示文摘 | Niwa H Miyazaki J Smith AG | 2000 | Nat Genet2000，24，4： | 1 |
| 20 | Determination of nicotine content and delivery in disposable electronic cigarettes available in the USA by gas chromatography-mass spectrometry 显示文摘 | Pagano T DiFrancesco AG Smith SB | 2015 | Nicotine Tob Res2015，，： | 1 |
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